JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

A Pilot Study of Trientine With Vemurafenib for the Treatment BRAF Mutated Metastatic Melanoma

Phase 1

Withdrawn

Conditions: Melanoma

Interventions: Drug: Vemurafenib and Trientine

First Posted Date: 2014-02-20

Last Posted Date: 2019-01-30

Lead Sponsor: Duke University

Registration Number: NCT02068079

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

The Use of Thromboelastometry (ROTEM) to Evaluate the Changes in Coagulation With Two Different Doses of Oxytocin Following Cesarean Delivery

Not Applicable

Withdrawn

Conditions: Coagulation Changes With Oxytocin

Interventions: Drug: Oxytocin

First Posted Date: 2014-02-14

Last Posted Date: 2015-12-16

Lead Sponsor: Duke University

Registration Number: NCT02063568

Locations: 🇺🇸
Duke University Hospital, Durham, North Carolina, United States

Pharmacokinetics of Dexmedetomidine in Children During Cardiopulmonary Bypass (CPB)

Completed

Conditions: Pharmacokinetics
Cardiopulmonary Bypass
Children

First Posted Date: 2014-02-11

Last Posted Date: 2014-11-24

Lead Sponsor: Duke University

Target Recruit Count: 18

Registration Number: NCT02059343

Locations: 🇺🇸
Duke University Hospital, Durham, North Carolina, United States

Efficacy and Safety of the DASH Diet in Adults With Moderate Chronic Kidney Disease: Pilot Study

Not Applicable

Completed

Conditions: Chronic Kidney Disease
Hypertension

Interventions: Other: DASH Diet
Other: Control Diet

First Posted Date: 2014-02-11

Last Posted Date: 2014-10-03

Lead Sponsor: Duke University

Target Recruit Count: 42

Registration Number: NCT02059811

Locations: 🇺🇸
Stedman Nutrition and Metabolism Center, Center for Living, Durham, North Carolina, United States

Use of Recombinant Hyaluronidase Human is Effective for the Use of Local Blocks for Eyelid's Surgery

Not Applicable

Withdrawn

Conditions: Upper Eyelid Surgery

Interventions: Drug: Hyaluronidase

First Posted Date: 2014-02-11

Last Posted Date: 2014-12-19

Lead Sponsor: Duke University

Registration Number: NCT02059694

Locations: 🇺🇸
Duke Eye Center, Durham, North Carolina, United States

Normal Eyelid Sensation Distribution

Not Applicable

Completed

Conditions: Normal Eyelid Sensation Distribution

Interventions: Device: Aesthesiometer

First Posted Date: 2014-02-11

Last Posted Date: 2017-02-27

Lead Sponsor: Duke University

Target Recruit Count: 30

Registration Number: NCT02059824

Locations: 🇺🇸
Duke Eye Center, Durham, North Carolina, United States

Ammonia Levels and Cognitive Impairment

Terminated

Conditions: Cognitive Impairment
Developmental Delay
Dementia
Cognitive Decline

First Posted Date: 2014-02-11

Last Posted Date: 2015-03-17

Lead Sponsor: Duke University

Target Recruit Count: 17

Registration Number: NCT02059356

Locations: 🇺🇸
Duke University Hospital, Durham, North Carolina, United States

Salvage Therapeutic Radiation With Enzalutamide and ADT in Men With Recurrent Prostate Cancer (STREAM)

Phase 2

Completed

Conditions: Prostate Cancer

Interventions: Drug: enzalutamide
Drug: Androgen Deprivation
Radiation: Radiation Therapy

First Posted Date: 2014-02-07

Last Posted Date: 2019-06-26

Lead Sponsor: Duke University

Target Recruit Count: 38

Registration Number: NCT02057939

Locations: 🇺🇸
Wake Forest Baptist Health, Winston-Salem, North Carolina, United States
🇺🇸
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, United States
🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Impact of Oral Antibiotic Treatment on C. Difficile

Phase 4

Completed

Conditions: C. Difficile
Diarrhea
Enterocolitis

Interventions: Drug: Fidaxomicin
Drug: Vancomycin
Drug: Metronidazole

First Posted Date: 2014-02-06

Last Posted Date: 2019-10-02

Lead Sponsor: Duke University

Target Recruit Count: 33

Registration Number: NCT02057198

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

School Reintegration After Pediatric Hematopoietic Stem Cell Transplant

Withdrawn

Conditions: Unspecified Complication of Bone Marrow Transplant

First Posted Date: 2014-02-03

Last Posted Date: 2015-02-04

Lead Sponsor: Duke University

Registration Number: NCT02052570

Locations: 🇺🇸
Duke University Health Systems, Durham, North Carolina, United States

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