JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Quantifying the Presence of Lung Disease and Pulmonary Hypertension in Children With Sickle Cell Disease

Phase 1

Completed

Conditions: Sickle Cell Disease

First Posted Date: 2013-07-11

Last Posted Date: 2014-12-03

Lead Sponsor: Duke University

Target Recruit Count: 5

Registration Number: NCT01895998

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Genetically Guided Statin Therapy

Not Applicable

Completed

Conditions: Hypercholesterolemia
Hydroxy-methylglutaryl-coenzyme A (HMG Co-A) Reductase Inhibitors Adverse Reaction

Interventions: Genetic: SLCO1B1*5 allele testing, results reported at end of study
Genetic: SLCO1B1*5 allele testing, results reported at randomization
Genetic: Genetic testing for SLCO1B1*5 allele

First Posted Date: 2013-07-10

Last Posted Date: 2017-06-23

Lead Sponsor: Duke University

Target Recruit Count: 167

Registration Number: NCT01894230

Locations: 🇺🇸
David Grant US Air Force Medical Center, Travis Air Force Base, California, United States
🇺🇸
Duke University, Durham, North Carolina, United States

The Early Truancy Prevention Project

Not Applicable

Completed

Conditions: Excessive Absenteeism by Primary School Students

Interventions: Behavioral: Teacher led intervention

First Posted Date: 2013-07-10

Last Posted Date: 2016-03-08

Lead Sponsor: Duke University

Target Recruit Count: 20

Registration Number: NCT01894464

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Statin Therapy to Improve Medication Adherence

Phase 1

Completed

Conditions: HMG COA Reductase Inhibitor Adverse Reaction
Hypercholesterolemia

Interventions: Genetic: Genetic testing and reporting for SLCO1B1*5 allele

First Posted Date: 2013-07-10

Last Posted Date: 2015-01-08

Lead Sponsor: Duke University

Target Recruit Count: 63

Registration Number: NCT01894217

Locations: 🇺🇸
Duke Primary Care Clinic at Pickett Road, Durham, North Carolina, United States
🇺🇸
Duke Center for Living, Durham, North Carolina, United States

Immunotherapy With CEA(6D) VRP Vaccine (AVX701) in Patients With Stage III Colorectal Cancer

Phase 1

Completed

Conditions: Stage III Colon Cancer

Interventions: Biological: AVX701

First Posted Date: 2013-07-01

Last Posted Date: 2019-07-18

Lead Sponsor: Duke University

Target Recruit Count: 12

Registration Number: NCT01890213

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Freezing of Gait in Parkinson's Disease

Not Applicable

Completed

Conditions: Parkinson Disease

Interventions: Other: Placebo group - non use of Tower of Hanoi
Device: Tower of Hanoi

First Posted Date: 2013-06-26

Last Posted Date: 2017-01-24

Lead Sponsor: Duke University

Target Recruit Count: 30

Registration Number: NCT01887054

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Safety and Efficacy of Albuterol in Individuals With Late-onset Pompe Disease

Phase 1

Completed

Conditions: Pompe Disease

Interventions: Drug: Placebo
Drug: Albuterol

First Posted Date: 2013-06-25

Last Posted Date: 2019-07-15

Lead Sponsor: Duke University

Target Recruit Count: 16

Registration Number: NCT01885936

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Genetic Risk and Health Coaching for Type 2 Diabetes and Coronary Heart Disease

Not Applicable

Completed

Conditions: Coronary Heart Disease, Susceptibility to, 5
Prediabetic State

Interventions: Genetic: Genetic risk counseling
Behavioral: Health coaching
Behavioral: Standard risk assessment

First Posted Date: 2013-06-24

Last Posted Date: 2018-04-24

Lead Sponsor: Duke University

Target Recruit Count: 220

Registration Number: NCT01884545

Locations: 🇺🇸
David Grant Medical Center, Fairfield, California, United States

KOREAN Enhanced RecOvery Strategy for Colorectal Surgery

Not Applicable

Terminated

Conditions: Goal-oriented Fluid Therapy
Colorectal Surgery

Interventions: Drug: Volulyte® (6% HES 130/0.4 in balanced solution)
Other: Combined epidural-general anesthesia (CEGA)
Other: Patient-Controlled Epidural Analgesia (PCEA)

First Posted Date: 2013-06-11

Last Posted Date: 2015-08-07

Lead Sponsor: Duke University

Target Recruit Count: 101

Registration Number: NCT01874730

Locations: 🇰🇷
Samsung Medical Center, Gangnam-Gu, Seoul, Korea, Republic of
🇰🇷
Yonsei University College of Medicine, Seodaemun-gu, Seoul, Korea, Republic of
🇰🇷
Asan Medical Center, Songpa-gu, Seoul, Korea, Republic of

Traditional African Healing Ceremony in a U.S. Population

Not Applicable

Completed

Conditions: Cancer
Chronic Fatigue Syndrome
Anxiety
Depression

Interventions: Behavioral: Movement to rhythm

First Posted Date: 2013-06-10

Last Posted Date: 2014-11-02

Lead Sponsor: Duke University

Target Recruit Count: 17

Registration Number: NCT01873482

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

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