JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Renal Optimization Strategies Evaluation in Acute Heart Failure and Reliable Evaluation of Dyspnea in the Heart Failure Network (ROSE) Study

Phase 2

Completed

Conditions: Acute Heart Failure

Interventions: Other: Placebo
Drug: Dopamine
Drug: Nesiritide

First Posted Date: 2010-05-28

Last Posted Date: 2014-08-21

Lead Sponsor: Duke University

Target Recruit Count: 360

Registration Number: NCT01132846

Locations: 🇺🇸
University of Utah Health Sciences Center, Murry, Utah, United States
🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
🇺🇸
University of Vermont- Fletcher Allen Health Care, Burlington, Vermont, United States

and more 5 locations

Neuroimaging of Smokers With and Without Attention Deficit Hyperactivity Disorder (ADHD)

Completed

Conditions: Smoking
ADHD

First Posted Date: 2010-05-14

Last Posted Date: 2018-11-08

Lead Sponsor: Duke University

Target Recruit Count: 101

Registration Number: NCT01123668

Locations: 🇺🇸
Duke Child and Family Study Center//Duke Health Behavior Neuroscience Research Program, Durham, North Carolina, United States

Epigenetic Modulation in Relapsed/Refractory Follicular Lymphoma and Marginal Zone Lymphoma

Phase 2

Terminated

Conditions: Follicular Lymphoma
Marginal Zone Lymphoma

Interventions: Drug: azacitidine
Drug: lenalidomide

First Posted Date: 2010-05-12

Last Posted Date: 2016-09-12

Lead Sponsor: Duke University

Target Recruit Count: 11

Registration Number: NCT01121757

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

"Pharmacokinetic Study of Fondaparinux in Inpatients With Renal Dysfunction"

Phase 1

Completed

Conditions: Renal Insufficiency

Interventions: Drug: fondaparinux sodium injection

First Posted Date: 2010-05-12

Last Posted Date: 2014-09-01

Lead Sponsor: Duke University

Target Recruit Count: 9

Registration Number: NCT01121770

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Stroke Education Intervention Trial - Pilot

Not Applicable

Completed

Conditions: Ischemic Stroke
Intracranial Hemorrhage
Transient Ischemic Attack

Interventions: Behavioral: stroke education

First Posted Date: 2010-05-04

Last Posted Date: 2015-10-14

Lead Sponsor: Duke University

Target Recruit Count: 30

Registration Number: NCT01115660

Locations: 🇺🇸
WFUBMC, Winston-Salem, North Carolina, United States

A Panobinostat Presurgery

Phase 2

Withdrawn

Conditions: Recurrent Glioblastoma

Interventions: Drug: panobinostat

First Posted Date: 2010-05-03

Last Posted Date: 2013-06-19

Lead Sponsor: Duke University

Registration Number: NCT01115036

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Phase II Study of Afinitor vs. Sutent in Patients With Metastatic Non-Clear Cell Renal Cell Carcinoma

Phase 2

Completed

Conditions: Advanced Non-clear Cell Renal Cell Carcinoma

Interventions: Drug: Everolimus
Drug: Sunitinib

First Posted Date: 2010-04-22

Last Posted Date: 2018-01-16

Lead Sponsor: Duke University

Target Recruit Count: 131

Registration Number: NCT01108445

Locations: 🇬🇧
The Royal Marsden NHS, London, England, United Kingdom
🇬🇧
Weston Park Hospital, Sheffield, England, United Kingdom
🇺🇸
Duke Univeristy Medical Center, Durham, North Carolina, United States

and more 15 locations

Fast Spectral Imaging Device for Tumor Margin Mapping

Completed

Conditions: Breast Cancer

First Posted Date: 2010-04-20

Last Posted Date: 2013-02-07

Lead Sponsor: Duke University

Target Recruit Count: 54

Registration Number: NCT01107080

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Cell Phone Intervention in Young Adults

Not Applicable

Completed

Conditions: Obesity

Interventions: Behavioral: Behavioral weight loss intervention

First Posted Date: 2010-03-24

Last Posted Date: 2017-11-13

Lead Sponsor: Duke University

Target Recruit Count: 365

Registration Number: NCT01092364

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Rivastigmine Study in Adolescents With Down Syndrome

Phase 1

Completed

Conditions: Down Syndrome

Interventions: Other: Liquid Placebo
Drug: Rivastigmine

First Posted Date: 2010-03-10

Last Posted Date: 2015-04-06

Lead Sponsor: Duke University

Target Recruit Count: 42

Registration Number: NCT01084135

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States
🇺🇸
Kennedy Krieger Institute, Baltimore, Maryland, United States

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