JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Impact of Maternal-infant Therapeutics on Safety, Mortality, and Disability

Withdrawn

Conditions: Gastroesophageal Reflux
Presumed Sepsis
Patent Ductus Arteriosus
Chronic Lung Disease
Neurodevelopmental Impairment

First Posted Date: 2009-12-09

Last Posted Date: 2013-01-16

Lead Sponsor: Duke University

Registration Number: NCT01028183

Locations: 🇺🇸
Duke Clinical Research Institute, Durham, North Carolina, United States

Radiosurgery and Avastin for Recurrent Malignant Gliomas

Not Applicable

Completed

Conditions: Malignant Glioma

Interventions: Radiation: Stereotactic Radiosurgery (SRS)
Drug: Bevacizumab

First Posted Date: 2009-11-20

Last Posted Date: 2014-02-28

Lead Sponsor: Duke University

Target Recruit Count: 15

Registration Number: NCT01017250

Locations: 🇺🇸
Duke University Medical Center, Radiation Oncology, Durham, North Carolina, United States

Vyvanse and Glucose Intolerance in Children With Attention Deficit Hyperactivity Disorder (ADHD) and Obesity

Phase 4

Terminated

Conditions: Attention Deficit Hyperactivity Disorder
Glucose Intolerance
Obesity

Interventions: Drug: Lis-dexamphetamine

First Posted Date: 2009-11-20

Last Posted Date: 2014-02-20

Lead Sponsor: Duke University

Target Recruit Count: 14

Registration Number: NCT01017263

Locations: 🇺🇸
Duke Child and Family Study Center, Durham, North Carolina, United States

Mechanism of the Blood Pressure Lowering Effect of the DASH Dietary Pattern

Not Applicable

Completed

Conditions: Blood Pressure

Interventions: Other: DASH, Control

First Posted Date: 2009-11-20

Last Posted Date: 2013-04-11

Lead Sponsor: Duke University

Target Recruit Count: 20

Registration Number: NCT01017484

Moderate to Persistent Asthma in the Obese Subject

Phase 4

Terminated

Conditions: Asthma

Interventions: Other: Sugar pill
Drug: Montelukast

First Posted Date: 2009-11-20

Last Posted Date: 2014-11-17

Lead Sponsor: Duke University

Target Recruit Count: 38

Registration Number: NCT01016847

Locations: 🇺🇸
Duke Asthma Allergy and Airway Center, Durham, North Carolina, United States

Optimal Planning Target Volume With Stereotactic Radiosurgery

Not Applicable

Completed

Conditions: Brain Cancer
Brain Neoplasms

Interventions: Radiation: Stereotactic Radiosurgery

First Posted Date: 2009-11-20

Last Posted Date: 2015-02-13

Lead Sponsor: Duke University

Target Recruit Count: 49

Registration Number: NCT01017497

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Avastin/Radiation (XRT)/Temozolomide (Temodar) Followed by Avastin/Temodar/Topotecan for Glioblastoma

Phase 2

Completed

Conditions: Gliosarcoma
Malignant Glioma
Glioblastoma

Interventions: Drug: Bevacizumab
Drug: Temozolomide
Radiation: Radiation Therapy (XRT)
Drug: Topotecan

First Posted Date: 2009-10-30

Last Posted Date: 2022-04-13

Lead Sponsor: Duke University

Target Recruit Count: 80

Registration Number: NCT01004874

Locations: 🇺🇸
The Preston Robert Tisch Brain Tumor Center at Duke, Durham, North Carolina, United States

Intervention Study of Communication in Oncologist-Patient Encounters

Not Applicable

Completed

Conditions: Advanced Cancer

Interventions: Behavioral: CHESS/COPE
Behavioral: CHESS
Behavioral: COPE

First Posted Date: 2009-10-14

Last Posted Date: 2014-09-12

Lead Sponsor: Duke University

Target Recruit Count: 659

Registration Number: NCT00994578

Locations: 🇺🇸
Duke University Health System, Durham, North Carolina, United States
🇺🇸
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States

The Effect of Depth of Anesthesia as Measured by Bispectral Index (BIS) on Emergence Agitation in Children

Not Applicable

Completed

Conditions: Emergence Agitation

Interventions: Other: Depth of anesthesia

First Posted Date: 2009-10-07

Last Posted Date: 2013-05-31

Lead Sponsor: Duke University

Target Recruit Count: 40

Registration Number: NCT00990769

Locations: 🇺🇸
Duke University Medical Center - Eye Center, Durham, North Carolina, United States

Cerebrospinal Fluid (CSF) Pharmacokinetics of Antimicrobials in Children

Completed

Conditions: Infections

First Posted Date: 2009-10-07

Last Posted Date: 2024-04-15

Lead Sponsor: Duke University

Target Recruit Count: 8

Registration Number: NCT00991185

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

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