JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

A Controlled Laboratory Study of the Effects on Cue-Induced Craving in Dependent Smokers

Phase 2

Completed

Conditions: Nicotine Dependence

Interventions: Device: Active rTMS Condition
Device: rTMS Frequency Control Condition
Device: rTMS Location Control Condition

First Posted Date: 2009-05-13

Last Posted Date: 2013-01-25

Lead Sponsor: Duke University

Target Recruit Count: 21

Registration Number: NCT00901459

Locations: 🇺🇸
Duke Center for Nicotine & Smoking Cessation Research, Durham, North Carolina, United States

Cervical Cancer Detection Using Optical Spectroscopy

Not Applicable

Recruiting

Conditions: Cervical Cancer

Interventions: Device: Optical Spectroscopy Bench-Top System
Device: Portable Optical Spectrometer
Device: Transvaginal colposcope

First Posted Date: 2009-05-13

Last Posted Date: 2025-02-28

Lead Sponsor: Duke University

Target Recruit Count: 350

Registration Number: NCT00900575

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Supporting Post Myocardial Infarction (MI) Risk Modification Intervention Via Telemedicine Evaluation

Not Applicable

Completed

Conditions: Cardiovascular Disease

Interventions: Behavioral: nurse intervention
Behavioral: web intervention

First Posted Date: 2009-05-13

Last Posted Date: 2014-09-08

Lead Sponsor: Duke University

Target Recruit Count: 416

Registration Number: NCT00901277

Evaluation of a Tailored Smoking Cessation Treatment Algorithm Based on Initial Treatment Response and Genotype

Phase 3

Completed

Conditions: Smoking Cessation

Interventions: Drug: Nicotine Patches
Drug: Nicotine patches, then nicotine patches (Pre-Quit)
Drug: Nicotine patches, then bupropion & nicotine patches (Post-Quit)
Drug: Nicotine patches, then varenicline (Post-Quit)
Drug: Nicotine patches, then nicotine patches (Post-Quit)
Drug: Nicotine patches, then bupropion & nicotine patches (Pre-Quit)
Drug: Nicotine patches, then varenicline (Pre-Quit)

First Posted Date: 2009-05-06

Last Posted Date: 2013-09-23

Lead Sponsor: Duke University

Target Recruit Count: 606

Registration Number: NCT00894166

Locations: 🇺🇸
Duke Center for Nicotine & Smoking Cessation Research, Charlotte, Durham, Raleigh, Winston-Salem, North Carolina, United States

Comparing the Effectiveness of New Versus Older Treatments for Attention Deficit Hyperactivity Disorder (The NOTA Study)

Phase 4

Completed

Conditions: Attention Deficit Disorder With Hyperactivity

Interventions: Drug: Methylphenidate transdermal system
Drug: Osmotic-release oral system methylphenidate (OROS MPH)
Drug: Mixed amphetamine salts extended release
Drug: Lisdexamfetamine dimesylate

First Posted Date: 2009-04-29

Last Posted Date: 2013-09-30

Lead Sponsor: Duke University

Target Recruit Count: 228

Registration Number: NCT00889915

Locations: 🇺🇸
Child and Adolescent Psychiatry Trials Network (CAPTN), Durham, North Carolina, United States

Spinal Cord Stimulator Implant Study

Not Applicable

Completed

Conditions: Back Pain

Interventions: Behavioral: Coping Skills Training
Behavioral: Education

First Posted Date: 2009-04-24

Last Posted Date: 2018-07-18

Lead Sponsor: Duke University

Target Recruit Count: 101

Registration Number: NCT00887419

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Impact of Temsirolimus Therapy on Circulating Tumor Cell Biology In Men With Castration Resistant Metastatic Prostate Cancer

Phase 2

Terminated

Conditions: Prostate Cancer

Interventions: Drug: Temsirolimus
Drug: Diphenhydramine

First Posted Date: 2009-04-24

Last Posted Date: 2014-02-26

Lead Sponsor: Duke University

Target Recruit Count: 11

Registration Number: NCT00887640

Locations: 🇺🇸
Virginia Oncology Associates, Norfolk, Virginia, United States
🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Mindfulness, Emotional Well-being, and Sleep Quality

Not Applicable

Completed

Conditions: Stress, Psychological
Sleep

Interventions: Behavioral: Mindfulness-Based Stress Reduction (MBSR)

First Posted Date: 2009-04-24

Last Posted Date: 2011-10-04

Lead Sponsor: Duke University

Target Recruit Count: 372

Registration Number: NCT00887614

Locations: 🇺🇸
Duke Integrative Medicine, Durham, North Carolina, United States

Treatment Effects of Escitalopram (Lexapro®) on Generalized Anxiety Disorder in Patients With HIV and AIDS

Phase 3

Completed

Conditions: Anxiety Disorders
HIV Infections

Interventions: Drug: Escitalopram

First Posted Date: 2009-04-24

Last Posted Date: 2014-10-31

Lead Sponsor: Duke University

Target Recruit Count: 30

Registration Number: NCT00887679

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Erectile Dysfunction Study

Not Applicable

Completed

Conditions: Erectile Dysfunction

Interventions: Other: aerobic exercise
Other: wait-list control

First Posted Date: 2009-04-01

Last Posted Date: 2013-10-28

Lead Sponsor: Duke University

Target Recruit Count: 64

Registration Number: NCT00873665

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

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