JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Inspiratory Pulmonary Rehabilitation for Children With Obesity and Asthma

Not Applicable

Recruiting

Conditions: Pediatric Obesity
Pediatric Asthma

Interventions: Device: Pro2 - 15% of participant's MIP
Device: Pro2 - 60% of participant's MIP

First Posted Date: 2022-11-08

Last Posted Date: 2024-11-13

Lead Sponsor: Duke University

Target Recruit Count: 60

Registration Number: NCT05608668

Locations: 🇺🇸
Duke Healthy Lifestyles Clinic, Durham, North Carolina, United States

Virtual Care to Improve Heart Failure Outcomes (VITAL-HF)

Not Applicable

Active, not recruiting

Conditions: Heart Failure With Reduced Ejection Fraction

Interventions: Other: Digital Heart Failure Medication Titration

First Posted Date: 2022-11-02

Last Posted Date: 2024-10-22

Lead Sponsor: Duke University

Target Recruit Count: 178

Registration Number: NCT05602454

Locations: 🇺🇸
Cardiovascular Institute of Northwest Florida, Panama City, Florida, United States
🇺🇸
Ascension St. Vincent, Indianapolis, Indiana, United States
🇺🇸
The University of Kansas Medical Center, Kansas City, Kansas, United States

and more 4 locations

Adolescents and Young Adults (AYAs) With Advanced Cancer

Not Applicable

Completed

Conditions: Adolescent and Young Adult Cancer Patient

Interventions: Behavioral: Education Control Arm
Behavioral: Symptom Management for Improved Physical and Emotional Wellbeing (SMILE)

First Posted Date: 2022-10-25

Last Posted Date: 2024-10-17

Lead Sponsor: Duke University

Target Recruit Count: 75

Registration Number: NCT05593016

Locations: 🇺🇸
Duke Cancer Institute, Durham, North Carolina, United States

ABC Blocks for Cardiac Surgery

Phase 4

Withdrawn

Conditions: Pain

Interventions: Drug: ABC block with bupivacaine/liposomal bupivacaine
Drug: ABC block with saline

First Posted Date: 2022-10-21

Last Posted Date: 2025-01-27

Lead Sponsor: Duke University

Target Recruit Count: 50

Registration Number: NCT05589363

Locations: 🇺🇸
Duke University Hospital, Durham, North Carolina, United States

You and Me Healthy

Conditions: COVID-19

First Posted Date: 2022-10-21

Last Posted Date: 2024-11-27

Lead Sponsor: Duke University

Target Recruit Count: 20000

Registration Number: NCT05589376

Locations: 🇺🇸
Greenville Pitt County, Greenville, North Carolina, United States
🇺🇸
Hamilton County, Chattanooga, Tennessee, United States
🇺🇸
Merced County, Merced, California, United States

ABC Mental Health: A Behavioral Study of K-12 Teachers and School Staff

Not Applicable

Completed

Conditions: Burnout, Professional
Self Efficacy
Mental Health Wellness 1

Interventions: Behavioral: Cultivating Awareness and Resilience in Education (CARE)

First Posted Date: 2022-10-12

Last Posted Date: 2024-11-11

Lead Sponsor: Duke University

Target Recruit Count: 53

Registration Number: NCT05574764

Locations: 🇺🇸
Caldwell County Schools, Lenoir, North Carolina, United States

CIC Behavioral Economics in Children With Spina Bifida

Not Applicable

Completed

Conditions: Neurogenic Bladder
Spina Bifida

Interventions: Behavioral: Present Bias without Loss Aversion
Behavioral: Present Bias with Loss Aversion

First Posted Date: 2022-10-03

Last Posted Date: 2024-06-06

Lead Sponsor: Duke University

Target Recruit Count: 22

Registration Number: NCT05562713

Locations: 🇺🇸
Lenox Baker Children's Hopsital, Durham, North Carolina, United States
🇺🇸
Duke University Hospital, Durham, North Carolina, United States

Measuring the Impact of an Enhanced Strategy for Daily Disinfection in Acute Care Hospital Rooms

Not Applicable

Completed

Conditions: Disinfection

Interventions: Other: Sani24
Other: Routine Disinfection

First Posted Date: 2022-09-29

Last Posted Date: 2022-09-29

Lead Sponsor: Duke University

Target Recruit Count: 50

Registration Number: NCT05560321

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Imaging Retinal Vasculature in Infant Eyes

Recruiting

Conditions: Retinopathy of Prematurity

Interventions: Device: Handheld Optical Coherence Tomography with OCT Angiography

First Posted Date: 2022-09-28

Last Posted Date: 2024-10-10

Lead Sponsor: Duke University

Target Recruit Count: 16

Registration Number: NCT05558059

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States
🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

PCSK9 Inhibitor and PD-1 Inhibitor in Patients With Metastatic, Refractory To Prior Anti PD-1 Non-small Cell Lung

Phase 2

Recruiting

Conditions: Non-small Cell Lung Cancer (NSCLC)

Interventions: Combination Product: Alirocumab and Cemiplimab

First Posted Date: 2022-09-23

Last Posted Date: 2024-05-24

Lead Sponsor: Duke University

Target Recruit Count: 60

Registration Number: NCT05553834

Locations: 🇺🇸
Moffitt Cancer Center, Tampa, Florida, United States
🇺🇸
Duke University, Durham, North Carolina, United States

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