JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Shared Decision Making to Address Racial Disparities in Oral Anticoagulation in NVAF

Not Applicable

Not yet recruiting

Conditions: Atrial Fibrillation

Interventions: Other: Patient Decision Support Tool

First Posted Date: 2021-07-09

Last Posted Date: 2025-05-30

Lead Sponsor: Duke University

Target Recruit Count: 40

Registration Number: NCT04956978

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Exercise Training to Promote Resilience to Chronic Lymphocytic Leukemia

Not Applicable

Completed

Conditions: Aging
Chronic Lymphocytic Leukemia

Interventions: Behavioral: Exercise Training

First Posted Date: 2021-07-06

Last Posted Date: 2021-07-06

Lead Sponsor: Duke University

Target Recruit Count: 20

Registration Number: NCT04950452

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Rapid Acceleration for Diagnostics in Underserved Populations: Home Testing

Completed

Conditions: COVID-19

Interventions: Behavioral: Behavioral questionaires

First Posted Date: 2021-07-02

Last Posted Date: 2023-09-22

Lead Sponsor: Duke University

Target Recruit Count: 338

Registration Number: NCT04949243

Locations: 🇺🇸
Hamilton County, Chattanooga, Tennessee, United States
🇺🇸
Greenville Pitt County, Greenville, North Carolina, United States

The PCSK9i Inhibitor Evolocumab - a Surgical Trial of Pharamcodynamics and Kinetics Evaluation

Early Phase 1

Completed

Conditions: Glioblastoma
Malignant Glioma

Interventions: Drug: Evolocumab

First Posted Date: 2021-06-24

Last Posted Date: 2024-06-25

Lead Sponsor: Duke University

Target Recruit Count: 32

Registration Number: NCT04937413

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

EngagINg the COmmunity to Reduce Preterm Birth Via Adherence To an Individualized Prematurity Prevention Plan

Not Applicable

Completed

Conditions: Preterm Birth

Interventions: Behavioral: Facebook discussions and Virtual group meetings

First Posted Date: 2021-06-22

Last Posted Date: 2024-11-04

Lead Sponsor: Duke University

Target Recruit Count: 31

Registration Number: NCT04933812

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Interventional Radiology Liver Directed Therapies and Hypofractionated Image-Guided Radiation Therapy in Veteran and Non-Veteran, Non-surgical Hepatocellular Carcinoma Patients

Not Applicable

Recruiting

Conditions: Liver Cancer

Interventions: Other: Quality of life questionnaires

First Posted Date: 2021-06-21

Last Posted Date: 2025-01-20

Lead Sponsor: Duke University

Target Recruit Count: 78

Registration Number: NCT04933435

Locations: 🇺🇸
Durham Veterans Administration Health Care System (DVAHCS), Durham, North Carolina, United States
🇺🇸
Duke Cancer Center, Durham, North Carolina, United States

Data-driven Approaches to Healthcare Provider Resilience & Burnout During COVID-19

Not Applicable

Terminated

Conditions: Exhaustion, Caregiver
Burnout, Professional
Covid19

Interventions: Behavioral: Transcendental Meditation (TM) and Experience Resolution Methodology (ERM)
Behavioral: Transcendental Meditation (TM)
Behavioral: Experience Resolution Methodology (ERM)
Behavioral: Treatment As Usual (TAU)

First Posted Date: 2021-06-10

Last Posted Date: 2023-04-21

Lead Sponsor: Duke University

Target Recruit Count: 212

Registration Number: NCT04922632

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Exercise and Soft Tissue Sarcoma

Not Applicable

Recruiting

Conditions: Soft Tissue Sarcoma

Interventions: Other: neoadjuvant exercise therapy

First Posted Date: 2021-06-10

Last Posted Date: 2025-04-17

Lead Sponsor: Duke University

Target Recruit Count: 24

Registration Number: NCT04921917

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Outcomes Database to prospectivelY aSSEss the Changing TherapY Landscape in Renal Cell Carcinoma

Recruiting

Conditions: Metastatic Renal Cell Carcinoma

First Posted Date: 2021-06-09

Last Posted Date: 2025-05-01

Lead Sponsor: Duke University

Target Recruit Count: 800

Registration Number: NCT04919122

Locations: 🇺🇸
State University of Iowa, Iowa City, Iowa, United States
🇺🇸
University of Kansas Medical Center, Kansas City, Kansas, United States
🇺🇸
The Johns Hopkins University, Baltimore, Maryland, United States

and more 8 locations

Balance Function in Patients Post Corona Virus Disease 2019 (COVID-19)

Completed

Conditions: Covid19

Interventions: Other: Balance assessments

First Posted Date: 2021-06-04

Last Posted Date: 2022-07-20

Lead Sponsor: Duke University

Target Recruit Count: 25

Registration Number: NCT04914364

Locations: 🇺🇸
Duke University Health System, Durham, North Carolina, United States

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