JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Sleep-Sensitive Seizure Risk Assessment With Wearable EEGs

Not Applicable

Not yet recruiting

Conditions: Epilepsy Intractable

Interventions: Device: Dreem headband

First Posted Date: 2024-08-09

Last Posted Date: 2025-03-19

Lead Sponsor: Duke University

Target Recruit Count: 35

Registration Number: NCT06545643

Locations: 🇺🇸
Duke University Health System, Durham, North Carolina, United States

Bacterial Decolonization Within Dyads

Not Applicable

Recruiting

Conditions: Bacterial Colonization

Interventions: Drug: Mupirocin
Drug: Chlorhexidine baths

First Posted Date: 2024-08-07

Last Posted Date: 2024-12-19

Lead Sponsor: Duke University

Target Recruit Count: 20

Registration Number: NCT06541145

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors

Not Applicable

Recruiting

Conditions: Post-traumatic Stress Disorder
Depression
Breath Shortness
Worries; Pain or Disability
Anxiety
Stress

Interventions: Behavioral: Blueprint
Behavioral: Education program

First Posted Date: 2024-08-05

Last Posted Date: 2024-11-22

Lead Sponsor: Duke University

Target Recruit Count: 400

Registration Number: NCT06538246

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Mindfulness Intervention for Sleep Disturbance and Symptom Management in Hematologic Cancer Patients During and After Inpatient Treatment

Not Applicable

Not yet recruiting

Conditions: Hematologic Malignancy

Interventions: Behavioral: Nite2Day+

First Posted Date: 2024-08-01

Last Posted Date: 2025-05-09

Lead Sponsor: Duke University

Target Recruit Count: 60

Registration Number: NCT06532773

Locations: 🇺🇸
2400 Pratt Street, Durham, North Carolina, United States

Adaptation and Pilot Testing of a Mindfulness-Based Insomnia and Symptom Management Intervention for Women With Breast Cancer Receiving Treatment in Rural Medically Underserved Areas

Not Applicable

Not yet recruiting

Conditions: Breast Cancer

Interventions: Behavioral: Mindfulness-Based Therapy for Insomnia with Cognitive-Behavioral Symptom Coping Skills

First Posted Date: 2024-07-31

Last Posted Date: 2025-05-15

Lead Sponsor: Duke University

Target Recruit Count: 15

Registration Number: NCT06529120

Liposomal Amphotericin B and Flucytosine Antifungal Strategy for Talaromycosis (LAmB-FAST)

Phase 3

Not yet recruiting

Conditions: Talaromycosis

Interventions: Drug: Flucytosine (5FC)
Drug: Flucytosine (5FC) placebo pill
Drug: Liposomal Amphotericin B (LAmB)
Drug: Deoxycholate Amphotericin B (DAmB)

First Posted Date: 2024-07-29

Last Posted Date: 2025-03-10

Lead Sponsor: Duke University

Target Recruit Count: 428

Registration Number: NCT06525389

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States
🇻🇳
Bach Mai Hospital, Hanoi, Vietnam
🇻🇳
National Hospital for Tropical Diseases, Hanoi, Vietnam

and more 2 locations

Ambient Digital Scribes Populating Clinical Notes

Not Applicable

Completed

Conditions: Patient Satisfaction
Clinician Satisfaction

Interventions: Other: Ambient Digital Scribes

First Posted Date: 2024-07-25

Last Posted Date: 2025-02-14

Lead Sponsor: Duke University

Target Recruit Count: 261

Registration Number: NCT06519123

Locations: 🇺🇸
Duke University Health System, Durham, North Carolina, United States

Optimizing Recovery in Trauma Patients by Integrating Enhanced Nutrition Delivery

Not Applicable

Not yet recruiting

Conditions: Trauma
Critical Illness

Interventions: Dietary Supplement: Nutrition Supplements - Fresubin KCAL Drinks

First Posted Date: 2024-07-25

Last Posted Date: 2025-02-28

Lead Sponsor: Duke University

Target Recruit Count: 60

Registration Number: NCT06521086

Locations: 🇺🇸
Duke University Hospital, Durham, North Carolina, United States

Immunogenicity of Influenza Vaccinations

Phase 4

Active, not recruiting

Conditions: Influenza

Interventions: Biological: Flublok (RIV) or Fluzone (IIV)
Biological: Flucelvax (ccIIV4)

First Posted Date: 2024-07-24

Last Posted Date: 2025-05-21

Lead Sponsor: Duke University

Target Recruit Count: 605

Registration Number: NCT06518577

Locations: 🇺🇸
Valleywise Health Comprehensive Health Center, Phoenix, Arizona, United States
🇺🇸
ASU Biodesign Institute, Tempe, Arizona, United States
🇺🇸
Centers for Disease Control and Prevention, Atlanta, Georgia, United States

and more 4 locations

Simultaneous mRNA COVID-19 and IIV Vaccination in Pregnancy Study

Phase 4

Recruiting

Conditions: Safety
Adverse Event Following Immunization
Birth Outcomes

Interventions: Biological: mRNA COVID-19 vaccine
Biological: IIV4 (quadrivalent inactivated influenza vaccine)

First Posted Date: 2024-07-16

Last Posted Date: 2024-10-03

Lead Sponsor: Duke University

Target Recruit Count: 350

Registration Number: NCT06503900

Locations: 🇺🇸
Emory University, Atlanta, Georgia, United States
🇺🇸
Centers for Disease Control and Prevention, Atlanta, Georgia, United States
🇺🇸
Boston Medical Center, Boston, Massachusetts, United States

and more 3 locations

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