DeepMed Research

JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

IMPRoving Outcomes in Vascular DisEase- Aortic Dissection

Not Applicable

Recruiting

Conditions: Type B Aortic Dissection

Interventions: Procedure: TEVAR
Other: Guideline directed medical therapy and surveillance of dissection

First Posted Date: 2023-10-17

Last Posted Date: 2025-04-01

Lead Sponsor: Duke University

Target Recruit Count: 1100

Registration Number: NCT06087029

Locations: 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸
University of California San Diego, San Diego, California, United States
🇺🇸
University of California, San Francisco, California, United States

and more 54 locations

A Multicenter Trial to Identify Optimal Atezolizumab Biomarkers in the Setting of Recurrent Glioblastoma. The MOAB Trial

Phase 2

Recruiting

Conditions: Recurrent Glioblastoma

Interventions: Drug: Atezolizumab

First Posted Date: 2023-10-06

Last Posted Date: 2025-01-24

Lead Sponsor: Duke University

Target Recruit Count: 80

Registration Number: NCT06069726

Locations: 🇺🇸
Saint Luke's Cancer Institute, Kansas City, Missouri, United States
🇺🇸
Duke University, Durham, North Carolina, United States
🇺🇸
Huntsman Cancer Institute, Salt Lake City, Utah, United States

Personalized Nutrition to Improve Recovery in Trauma

Phase 2

Recruiting

Conditions: Abdominal Trauma

Interventions: Dietary Supplement: Nutrition Supplement

First Posted Date: 2023-10-03

Last Posted Date: 2024-10-17

Lead Sponsor: Duke University

Target Recruit Count: 150

Registration Number: NCT06065202

Locations: 🇺🇸
Duke University Hospital, Durham, North Carolina, United States

Partial Heart Transplantation

Not Applicable

Suspended

Conditions: Congenital Heart Disease

Interventions: Procedure: Partial Heart Transplantation
Other: Freshly procured valve

First Posted Date: 2023-09-26

Last Posted Date: 2025-02-28

Lead Sponsor: Duke University

Target Recruit Count: 15

Registration Number: NCT06055556

Locations: 🇺🇸
Duke University Hospital, Durham, North Carolina, United States

Treating Psychosocial Distress in Glaucoma

Not Applicable

Recruiting

Conditions: Depression
Glaucoma, Primary Open Angle
Distress, Emotional
Anxiety

Interventions: Behavioral: Acceptance commitment therapy

First Posted Date: 2023-09-25

Last Posted Date: 2025-05-18

Lead Sponsor: Duke University

Target Recruit Count: 45

Registration Number: NCT06053307

Locations: 🇺🇸
Duke University Eye Center, Durham, North Carolina, United States

Effect of Acetylcholinesterase Inhibitors on Bone Metabolism

Phase 2

Recruiting

Conditions: Osteoporosis

Interventions: Drug: Placebo
Drug: Donepezil

First Posted Date: 2023-09-18

Last Posted Date: 2025-02-05

Lead Sponsor: Duke University

Target Recruit Count: 45

Registration Number: NCT06041789

Locations: 🇺🇸
Duke Memory Disorders Clinic, Durham, North Carolina, United States

Glioblastoma Psychosocial Support Program

Not Applicable

Completed

Conditions: Glioblastoma

Interventions: Behavioral: Psychosocial Support Intervention

First Posted Date: 2023-09-15

Last Posted Date: 2024-07-31

Lead Sponsor: Duke University

Target Recruit Count: 11

Registration Number: NCT06038604

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Safety of Simultaneous mRNA COVID-19 Vaccine With Other Childhood Vaccines in Young Children

Phase 4

Recruiting

Conditions: Fever After Vaccination
Fever
Seizures Fever

Interventions: Biological: mRNA COVID-19 Vaccine
Biological: Routine Childhood Vaccinations

First Posted Date: 2023-09-15

Last Posted Date: 2025-03-25

Lead Sponsor: Duke University

Target Recruit Count: 600

Registration Number: NCT06038617

Locations: 🇺🇸
Kaiser Permanente Northern California, Oakland, California, United States
🇺🇸
Centers for Disease Control and Prevention, Atlanta, Georgia, United States
🇺🇸
Columbia University, New York, New York, United States

and more 2 locations

Project HOPES: Healthy Options for Pain and Ending Smoking. A Program for Cancer Survivors.

Phase 4

Active, not recruiting

Conditions: Pain
Smoking Cessation

Interventions: Other: Smoking cessation and pain management intervention
Drug: Varenicline

First Posted Date: 2023-09-08

Last Posted Date: 2025-03-19

Lead Sponsor: Duke University

Target Recruit Count: 20

Registration Number: NCT06029907

Locations: 🇺🇸
Duke University Health System, Durham, North Carolina, United States

Comparative Immunogenicity of Concomitant vs Sequential mRNA COVID-19 and Influenza Vaccinations

Phase 4

Completed

Conditions: Influenza
COVID-19

Interventions: Biological: Sequential Vaccination (mRNA COVID booster then Influenza vaccine)
Biological: Sequential Vaccination (Influenza vaccine then mRNA COVID booster)
Biological: Simultaneous Vaccination (Influenza Vaccine and mRNA COVID booster)

First Posted Date: 2023-08-31

Last Posted Date: 2024-05-31

Lead Sponsor: Duke University

Target Recruit Count: 455

Registration Number: NCT06020118

Locations: 🇺🇸
Washington University IDCRU, Saint Louis, Missouri, United States
🇺🇸
VA Northeast Ohio Healthcare System (VANEOHS), Cleveland, Ohio, United States
🇺🇸
Valleywise Health Comprehensive Health Center, Phoenix, Arizona, United States

and more 5 locations

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