JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Micra AV Tracking During Exercise Testing

Phase 4

Withdrawn

Conditions: Heart Block AV

Interventions: Device: Medtronic Micra AV Device

First Posted Date: 2023-07-28

Last Posted Date: 2024-04-17

Lead Sponsor: Duke University

Registration Number: NCT05966168

Locations: 🇺🇸
Duke University Health System, Durham, North Carolina, United States

A Depression and Opioid Pragmatic Trial in Pharmacogenetics (Depression Trial)

Not Applicable

Completed

Conditions: Depression

Interventions: Other: Pharmacogenetic testing
Other: Clinical decisions support

First Posted Date: 2023-07-28

Last Posted Date: 2025-01-10

Lead Sponsor: Duke University

Target Recruit Count: 1461

Registration Number: NCT05966155

Locations: 🇺🇸
University of Florida - Gainesville, Gainesville, Florida, United States
🇺🇸
Nashville General Hospital, Nashville, Tennessee, United States
🇺🇸
Eskenazi Health, Indianapolis, Indiana, United States

and more 9 locations

A Depression and Opioid Pragmatic Trial in Pharmacogenetics (Acute Pain Trial)

Not Applicable

Completed

Conditions: Acute Pain

Interventions: Other: Pharmacogenetic testing
Other: Clinical decisions support

First Posted Date: 2023-07-28

Last Posted Date: 2025-01-09

Lead Sponsor: Duke University

Target Recruit Count: 1602

Registration Number: NCT05966129

Locations: 🇺🇸
Nashville General Hospital, Nashville, Tennessee, United States
🇺🇸
Duke University Medical Center, Durham, North Carolina, United States
🇺🇸
Icahn School of Medicine at Mount Sinai, New York, New York, United States

and more 6 locations

RECOVER-NEURO: Platform Protocol, Appendix_A to Measure the Effects of BrainHQ, PASC CoRE and tDCS Interventions on Long COVID Symptoms

Not Applicable

Completed

Conditions: Long Covid-19
Long COVID
Long Covid19

Interventions: Other: BrainHQ/Active Comparator Activity
Other: BrainHQ
Device: tDCS-active
Other: PASC CoRE
Device: tDCS-sham

First Posted Date: 2023-07-28

Last Posted Date: 2025-05-04

Lead Sponsor: Duke University

Target Recruit Count: 328

Registration Number: NCT05965739

Locations: 🇺🇸
All sites listed under NCT05965752, Durham, North Carolina, United States

RECOVER-NEURO: Platform Protocol to Measure the Effects of Cognitive Dysfunction Interventions on Long COVID Symptoms

Not Applicable

Completed

Conditions: Long COVID
Long Covid19
Long Covid-19

Interventions: Other: BrainHQ/Active Comparator Activity
Other: BrainHQ
Other: PASC CoRE
Device: tDCS-active
Device: tDCS-sham

First Posted Date: 2023-07-28

Last Posted Date: 2025-02-27

Lead Sponsor: Duke University

Target Recruit Count: 328

Registration Number: NCT05965752

Locations: 🇺🇸
Ronald Reagan UCLA Medical Center, Los Angeles, California, United States
🇺🇸
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, United States
🇺🇸
Rush University Medical Center, Chicago, Illinois, United States

and more 21 locations

Improving Physician Vaccine Recommendation Using Social Norms, Trust, and Presumptive Language

Not Applicable

Completed

Conditions: Healthy

Interventions: Other: Quantity of vaccination recommendations
Other: Control
Other: Quality of vaccination recommendations

First Posted Date: 2023-07-24

Last Posted Date: 2024-05-01

Lead Sponsor: Duke University

Target Recruit Count: 447

Registration Number: NCT05957393

Locations: 🇺🇸
Duke University Health System (all locations), Durham, North Carolina, United States
🇺🇸
(Any and all facilities) - The study team ask(s)/(ed) professional contacts, friends, and family members who are employed at various US Institutions to forward the recruitment announcement message via their respective networks, Durham, North Carolina, United States
🇧🇷
(Any and all facilities) - Participants are recruited via market research company "Survey Healthcare Global", Brasília, Brazil

Tributyrin to Promote Gut Health Among Children Undergoing Hematopoietic Cell Transplantation

Early Phase 1

Withdrawn

Conditions: Hematopoietic Cell Transplantation (HCT)

Interventions: Combination Product: Tributyrin

First Posted Date: 2023-07-18

Last Posted Date: 2024-08-15

Lead Sponsor: Duke University

Registration Number: NCT05951153

Mechanistic Study of Inspiratory Training in Childhood Asthma (MICA)

Not Applicable

Recruiting

Conditions: Asthma in Children
Obesity
Pediatric Obesity
Pediatric Asthma

Interventions: Device: Pro2 - High Dose - 75% of participant's MIP
Device: Pro2 - Low Dose - 40% of participant's MIP
Device: Pro2 - SHAM - 15% of participant's MIP

First Posted Date: 2023-07-14

Last Posted Date: 2024-11-14

Lead Sponsor: Duke University

Target Recruit Count: 76

Registration Number: NCT05945355

Locations: 🇺🇸
Duke Health Center Creekstone, Durham, North Carolina, United States
🇺🇸
Duke Healthy Lifestyles Clinic, Durham, North Carolina, United States