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GlaxoSmithKline

GlaxoSmithKline logo
🇬🇧United Kingdom
Ownership
Public
Established
1929-01-01
Employees
70.2K
Market Cap
$90B
Website
http://www.gsk.com
Introduction

GSK Plc is a healthcare company, which engages in the research, development, and manufacture of pharmaceutical medicines, vaccines, and consumer healthcare products. It operates through the Commercial Operations, and Research and Development segments. The Commercial Operations segment has three product groups of specialty medicines, vaccines, and general medicines. The company was founded in 1715 and is headquartered in Middlesex, the United Kingdom.

Clinical Trials

3.8k

Active:155
Completed:3200

Trial Phases

5 Phases

Phase 1:1096
Phase 2:827
Phase 3:937
+2 more phases

Drug Approvals

126

PPB:126

Drug Approvals

OMJJARA TABLETS 100MG

Approval Date
Dec 13, 2024
PPB

OMJJARA TABLETS 150MG

Approval Date
Dec 13, 2024
PPB

OMJJARA TABLETS 200MG

Approval Date
Dec 13, 2024
PPB

DERMOVATE CREAM 0.05% W/W

Approval Date
Oct 12, 2023
PPB

DERMOVATE OINTMENT 0.05% W/W

Approval Date
Oct 12, 2023
PPB
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Clinical Trials

Distribution across different clinical trial phases (3318 trials with phase data)• Click on a phase to view related trials

Phase 1
1096 (33.0%)
Phase 3
937 (28.2%)
Phase 2
827 (24.9%)
Phase 4
339 (10.2%)
Not Applicable
119 (3.6%)

A Study to Evaluate Safety, Reactogenicity, and Immunogenicity of the GSK 4-component Strep A Vaccine With Aluminum Hydroxide (Alum) or AS37 in Healthy Young Adults

Not Applicable
Not yet recruiting
Conditions
Streptococcal Infections
Interventions
Biological: Low dose Strep A Alum
Biological: Medium dose Strep A Alum
Biological: High dose Strep A Alum
Biological: Low dose Strep A AS37
Biological: Medium dose Strep A AS37
Biological: High dose Strep A AS37
Drug: Strep A Alum Placebo
First Posted Date
2025-07-25
Last Posted Date
2025-07-25
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
108
Registration Number
NCT07085702
Locations
🇦🇺

GSK Investigational Site, Camberwell, Victoria, Australia

Sub-study of Belantamab Mafodotin (GSK2857916) in Combination With Nirogacestat in Participants With RRMM

Not Applicable
Active, not recruiting
Conditions
Multiple Myeloma
Interventions
First Posted Date
2025-07-25
Last Posted Date
2025-07-25
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
106
Registration Number
NCT07084896
Locations
🇺🇸

238995, Atlanta, Georgia, United States

🇺🇸

240593, Boston, Massachusetts, United States

🇺🇸

251164, Grand Rapids, Michigan, United States

and more 2 locations

A Study to Assess the Safety and Immunogenicity of a Vaccine Against Malaria in Healthy Children Aged 5-60 Months

Phase 2
Not yet recruiting
Conditions
Malaria
Interventions
Biological: RTS,S/AS01E vaccine
First Posted Date
2025-06-25
Last Posted Date
2025-06-25
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
238
Registration Number
NCT07036159
Locations
🇷🇼

Center for Family Health Research, Kigali, Rwanda

🇷🇼

Rinda Ubuzima Gatenga Medicalized Health Center University of Rwanda, Kigali, Rwanda

A Phase 3 Study to Assess the Immune Response And Safety Of Rmenb+Omv Nz In Primed Healthy Participants (10 To 20 Years Old)

Phase 3
Not yet recruiting
Conditions
Meningitis
Interventions
Biological: rMenB+OMV NZ vaccine
First Posted Date
2025-05-29
Last Posted Date
2025-05-29
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
312
Registration Number
NCT06995430

A Study of GSK5458514 Administered Alone or In Combination With Other Anti-Cancer Agents in Participants With Prostate Cancer

Phase 1
Recruiting
Conditions
Neoplasms, Prostate
Interventions
Drug: GSK5458514
First Posted Date
2025-05-25
Last Posted Date
2025-06-29
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
82
Registration Number
NCT06990880
Locations
🇯🇵

GSK Investigational Site, Tokyo, Japan

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News

GSK Secures $12.5 Billion Deal with Hengrui for COPD Drug and 11 Additional Programs

GSK has entered into agreements with Chinese pharmaceutical company Hengrui worth up to $12.5 billion for exclusive global rights to develop 12 innovative medicines, including a potential best-in-class COPD treatment.

GSK Advances Dostarlimab in Phase 3 Colon Cancer Trial and Phase 2 Endometrial Cancer Study

GSK is conducting a Phase 3 randomized trial evaluating perioperative dostarlimab monotherapy versus standard of care in patients with untreated T4N0 or Stage III dMMR/MSI-H resectable colon cancer.

FDA Advisory Panel Rejects GSK's Blenrep Combination Therapies for Multiple Myeloma

FDA advisers voted 5-3 against approving GSK's Blenrep in combination with bortezomib and dexamethasone for relapsed or refractory multiple myeloma patients.

FDA Advisory Panel Votes Against GSK's Blenrep for Multiple Myeloma Over Eye Safety Concerns

FDA advisers voted that the risks of GSK's blood cancer drug Blenrep outweigh its benefits in treating multiple myeloma, citing serious eye-related side effects as a primary concern.

FDA Raises Eye Safety Concerns for GSK's Blenrep Ahead of Advisory Committee Review

The FDA has identified significant ocular toxicity concerns with GSK's Blenrep (belantamab mafodotin) ahead of a July 17 advisory committee meeting to review the drug's reintroduction to the U.S. market.

ViiV Healthcare Expands Generic License for Long-Acting HIV Treatment to 133 Countries

ViiV Healthcare has expanded its voluntary licensing agreement with the Medicines Patent Pool to allow generic production of cabotegravir for HIV treatment in 133 countries, including all low-income and Sub-Saharan African nations.

Nature Study Validates LIXTE's PP2A Inhibitor LB-100 for Enhanced Cancer Immunotherapy

A Nature study led by MD Anderson researchers found that ovarian cancer patients with PPP2R1A mutations had significantly better overall survival when treated with immune checkpoint blockade therapy.

ViiV Healthcare Presents Real-World Data on Long-Acting HIV Treatments at IAS 2025

ViiV Healthcare presented extensive real-world data at IAS 2025 demonstrating the effectiveness, safety, and tolerability of its long-acting injectable HIV treatments, including cabotegravir + rilpivirine LA for treatment and cabotegravir LA for prevention.

Hansa Biopharma Appoints Dr. Richard Philipson as Chief Medical Officer to Lead Next Development Phase

Hansa Biopharma has appointed Dr. Richard Philipson as Chief Medical Officer effective July 14, bringing over 25 years of industry experience to the commercial-stage biopharmaceutical company.

House Republicans Subpoena Former Pfizer Executive Over Alleged COVID-19 Vaccine Trial Delays

House Judiciary Committee subpoenaed former Pfizer executive Dr. Philip Dormitzer over allegations that senior Pfizer executives deliberately slowed COVID-19 vaccine clinical testing before the 2020 election.

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