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GlaxoSmithKline

GlaxoSmithKline logo
πŸ‡¬πŸ‡§United Kingdom
Ownership
Public
Established
1929-01-01
Employees
70.2K
Market Cap
$90B
Website
http://www.gsk.com
Introduction

GSK Plc is a healthcare company, which engages in the research, development, and manufacture of pharmaceutical medicines, vaccines, and consumer healthcare products. It operates through the Commercial Operations, and Research and Development segments. The Commercial Operations segment has three product groups of specialty medicines, vaccines, and general medicines. The company was founded in 1715 and is headquartered in Middlesex, the United Kingdom.

Clinical Trials

3.8k

Active:158
Completed:3210

Trial Phases

5 Phases

Phase 1:1096
Phase 2:827
Phase 3:937
+2 more phases

Drug Approvals

126

PPB:126

Drug Approvals

OMJJARA TABLETS 100MG

Approval Date
Dec 13, 2024
PPB

OMJJARA TABLETS 150MG

Approval Date
Dec 13, 2024
PPB

OMJJARA TABLETS 200MG

Approval Date
Dec 13, 2024
PPB

DERMOVATE CREAM 0.05% W/W

Approval Date
Oct 12, 2023
PPB

DERMOVATE OINTMENT 0.05% W/W

Approval Date
Oct 12, 2023
PPB
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Clinical Trials

Distribution across different clinical trial phases (3337 trials with phase data)β€’ Click on a phase to view related trials

Phase 1
1096 (32.8%)
Phase 3
937 (28.1%)
Phase 2
827 (24.8%)
Phase 4
339 (10.2%)
Not Applicable
138 (4.1%)

A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH

Not Applicable
Not yet recruiting
Conditions
Non-alcoholic Fatty Liver Disease
Interventions
First Posted Date
2025-10-27
Last Posted Date
2025-10-27
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
1200
Registration Number
NCT07221227
Locations
πŸ‡ΊπŸ‡Έ

GSK Investigational Site, Miami, Florida, United States

A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected F2- or F3-stage MASH

Not Applicable
Not yet recruiting
Conditions
Non-alcoholic Fatty Liver Disease
Interventions
First Posted Date
2025-10-27
Last Posted Date
2025-10-27
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
1250
Registration Number
NCT07221188

A Study on the Immune Response and Safety of Vaccine Against Respiratory Syncytial Virus Given to Chinese Adults 18 to 59 Years of Age at Increased Risk of Respiratory Syncytial Virus Disease

Not Applicable
Not yet recruiting
Conditions
Respiratory Syncytial Virus Infections
Interventions
First Posted Date
2025-10-23
Last Posted Date
2025-10-23
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
750
Registration Number
NCT07220109

A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy

Not Applicable
Not yet recruiting
Conditions
Gastrointestinal Neoplasms
Interventions
First Posted Date
2025-10-21
Last Posted Date
2025-10-21
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
450
Registration Number
NCT07218926

Sub-study of Belantamab Mafodotin (GSK2857916) in Combination With Feladilimab (GSK3359609) in Participants With RRMM

Not Applicable
Active, not recruiting
Conditions
Multiple Myeloma
Interventions
First Posted Date
2025-10-15
Last Posted Date
2025-10-15
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
25
Registration Number
NCT07217119
Locations
πŸ‡ΈπŸ‡ͺ

GSK Investigational Site, Stockholm, Sweden

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News

GSK Secures $745M License Deal for Novel COPD siRNA Therapy, Receives Orphan Drug Status for Cancer ADC

GSK entered a worldwide exclusive license agreement with Empirico for EMP-012, a first-in-class siRNA targeting a novel therapeutic pathway for COPD treatment, with potential expansion to other inflammatory respiratory diseases.

GSK Acquires Exclusive Rights to Syndivia's Preclinical ADC for Metastatic Castration-Resistant Prostate Cancer

GSK has secured exclusive worldwide rights to develop and commercialize a preclinical antibody-drug conjugate from Syndivia targeting metastatic castration-resistant prostate cancer, with potential payments up to Β£268 million.

GSK's Next-Generation Low-Carbon Ventolin Inhaler Shows Therapeutic Equivalence in Phase III Trial

GSK announced positive phase III data demonstrating therapeutic equivalence and comparable safety between its next-generation low-carbon Ventolin (salbutamol) inhaler using HFA-152a propellant and the current HFA-134a formulation.

Alector's Latozinemab Fails Phase III Trial for Frontotemporal Dementia, Company Cuts Workforce by Half

Alector's investigational antibody latozinemab failed to slow disease progression in a 96-week Phase III trial for frontotemporal dementia caused by progranulin gene mutations.

Dovato Demonstrates Non-Inferior Efficacy to Biktarvy with Significantly Less Weight Gain in 96-Week HIV Treatment Study

ViiV Healthcare's PASO DOBLE trial shows Dovato (DTG/3TC) maintains viral suppression as effectively as Biktarvy (BIC/FTC/TAF) at 96 weeks in 553 virologically suppressed HIV-1 patients.

NICE Approves Long-Acting HIV Prevention Injection for England and Wales

The National Institute for Health and Care Excellence (NICE) has recommended cabotegravir long-acting injection for HIV prevention in England and Wales, offering an alternative to daily oral PrEP for high-risk individuals who cannot take oral medications.

Activist Investor Shah Capital Calls for Novavax Sale Amid COVID Vaccine Market Share Struggles

Shah Capital, Novavax's second-largest shareholder with a 7.2% stake, has urged the company's board to pursue a sale, citing three consecutive years of poor COVID-19 vaccine performance.

Clover Biopharmaceuticals Reports Positive Phase I Data for First-in-Class RSV-hMPV-PIV3 Combination Vaccines

Clover's combination vaccines SCB-1022 and SCB-1033 demonstrated robust immune responses with 6-8 fold increases in RSV neutralizing antibodies, 6-9 fold increases for hMPV, and 4 fold increases for PIV3 in older adults.

New Report Analyzes 1,775 Clinical-Stage Pharma Partnerships from 2020-2025

ResearchAndMarkets.com released a comprehensive report analyzing 1,775 clinical-stage partnering deals in pharma and biotech from 2020-2025, providing detailed financial terms and strategic insights.

GC Biopharma Partners with Curevo Vaccine to Manufacture Next-Generation Shingles Vaccine with Improved Tolerability

GC Biopharma has secured contract manufacturing rights for amezosvatein (CRV-101), a recombinant shingles vaccine designed to reduce injection-site pain and systemic reactions compared to current market leader Shingrix.

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