MedPath

Rivus Pharmaceuticals, Inc.

Rivus Pharmaceuticals, Inc. logo
🇺🇸United States
Ownership
Holding
Established
2019-01-01
Employees
11
Market Cap
-
Website
http://www.rivuspharma.com

Relative Bioavailability Study of HU6

Phase 1
Recruiting
Conditions
Healthy
Interventions
Drug: HU6 150 mg Capsules x 3 (Total dose = 450 mg)
Drug: HU6 450 mg Tablet
First Posted Date
2024-07-03
Last Posted Date
2024-08-28
Lead Sponsor
Rivus Pharmaceuticals, Inc.
Target Recruit Count
40
Registration Number
NCT06486558
Locations
🇺🇸

Nucleus Network, Saint Paul, Minnesota, United States

A Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-HU6

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: [14C]-HU6
First Posted Date
2024-03-22
Last Posted Date
2024-05-21
Lead Sponsor
Rivus Pharmaceuticals, Inc.
Target Recruit Count
8
Registration Number
NCT06325930
Locations
🇺🇸

Pharmaron Clinical Pharmacology Center (CPC), Baltimore, Maryland, United States

Ph 2a Study of HU6 on Energy Metabolism, Muscle and Liver Substrate Metabolism, and Mitochondrial Function in Subjects Who Are Overweight or Obese With Type 2 Diabetes

Phase 2
Withdrawn
Conditions
Diabete Type 2
Obesity
Interventions
Drug: HU6
First Posted Date
2023-10-27
Last Posted Date
2024-01-09
Lead Sponsor
Rivus Pharmaceuticals, Inc.
Registration Number
NCT06104358
Locations
🇺🇸

AdventHealth Translational Research Institute, Orlando, Florida, United States

Ph 2 Study of the Safety and Efficacy of Three HU6 Dose Levels and Placebo in Nonalcoholic Steatohepatitis

Phase 2
Active, not recruiting
Conditions
Fatty Liver
Non-Alcoholic Fatty Liver Disease
Nonalcoholic Steatohepatitis
Interventions
Other: Placebo
Drug: HU6
First Posted Date
2023-08-07
Last Posted Date
2024-07-22
Lead Sponsor
Rivus Pharmaceuticals, Inc.
Target Recruit Count
219
Registration Number
NCT05979779
Locations
🇺🇸

Velocity Clinical Research, Los Angeles, California, United States

🇺🇸

Panax Clinical Research, Miami Lakes, Florida, United States

🇺🇸

CenExel HRI, Berlin, New Jersey, United States

and more 17 locations

Safety and Pharmacokinetics of HU6

Phase 1
Completed
Conditions
Obese
Interventions
Drug: HU6 Tablet
Drug: HU6 Capsule
First Posted Date
2022-06-27
Last Posted Date
2023-03-20
Lead Sponsor
Rivus Pharmaceuticals, Inc.
Target Recruit Count
30
Registration Number
NCT05433506
Locations
🇺🇸

Nucleus Network, Minneapolis, Minnesota, United States

Exploratory Ph 2A, Double-Blind, Placebo-Controlled Dose Escalation Study of Safety, Tolerability, PD, & PK of HU6 for Subjects With Obese HFpEF

Phase 2
Completed
Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
Drug: Placebo
Drug: HU6
First Posted Date
2022-03-17
Last Posted Date
2024-08-26
Lead Sponsor
Rivus Pharmaceuticals, Inc.
Target Recruit Count
67
Registration Number
NCT05284617
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

Lundquist Institute for Biomedical Innovation at Harbor UCLA Medical Center, Torrance, California, United States

🇺🇸

Weill Cornell Medicine, New York, New York, United States

and more 12 locations

Phase 2a Study of HU6 in Subjects With Elevated Liver Fat and High BMI Volunteers

Phase 2
Completed
Conditions
NASH - Nonalcoholic Steatohepatitis
Interventions
Drug: HU6
Drug: Placebo
First Posted Date
2021-05-05
Last Posted Date
2024-03-01
Lead Sponsor
Rivus Pharmaceuticals, Inc.
Target Recruit Count
80
Registration Number
NCT04874233
Locations
🇺🇸

Prism Clinical Research, Minneapolis, Minnesota, United States

Multiple Ascending Dose Study of HU6 in High BMI Volunteers

Phase 1
Completed
Conditions
NASH - Nonalcoholic Steatohepatitis
Interventions
Drug: HU6
First Posted Date
2021-01-14
Last Posted Date
2021-08-16
Lead Sponsor
Rivus Pharmaceuticals, Inc.
Target Recruit Count
30
Registration Number
NCT04709913
Locations
🇺🇸

Prism Clinical Research, Minneapolis, Minnesota, United States

Ascending Dose Study of HU6 in Healthy Volunteers

Phase 1
Completed
Conditions
NASH - Nonalcoholic Steatohepatitis
Interventions
Drug: HU6
First Posted Date
2020-07-09
Last Posted Date
2021-05-04
Lead Sponsor
Rivus Pharmaceuticals, Inc.
Target Recruit Count
64
Registration Number
NCT04463017
Locations
🇺🇸

Prism Clinical Research, Saint Paul, Minnesota, United States

© Copyright 2025. All Rights Reserved by MedPath