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CSTONE PHARMA-B

🇭🇰Hong Kong, China
Ownership
-
Established
2018-12-13
Employees
164
Market Cap
-
Website
http://www.cstonepharma.com
Introduction

Cornerstone Pharmaceutical was created to meet the needs of cancer patients and focuses on developing and commercializing innovative tumor immunotherapy and molecular-targeted drugs. Since its establishment 3 years ago, the company has assembled a world-class management team with rich experience in preclinical research, clinical development and commercialization.

Through a dual source of innovation consisting of internal R&D and external collaboration, the company has built a powerful anti-tumor drug pipeline with 14 drug candidates, including 4 products exclusively collaborated and authorized by Blueprint Medicine and Agios Pharmaceuticals. Together with the self-developed pipeline, the company has significant potential and synergistic effects for single and combination therapies. Of the drug candidates under development, 4 are in or close to critical trials. Cornerstone Pharmaceutical's business model is driven by clinical research and development, while rapidly establishing commercialization and production capacity.

The company received support from well-known investors, and both the A and B rounds of financing broke records in the biomedical field at the time, with a total amount of 412 million US dollars in the two rounds of financing.

With an experienced team, a promising R&D pipeline, a strong business model, and sustainable financial support, Cornerstone's vision is to become a world-renowned leading Chinese biopharmaceutical company by bringing innovative and differentiated oncology therapies to cancer patients around the world.

A Phase Ib/II Study of Fisogatinib(BLU-554) in Subjects With Hepatocellular Carcinoma

Phase 1
Completed
Conditions
Hepatocellular Carcinoma
First Posted Date
2019-12-11
Last Posted Date
2023-02-06
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
26
Registration Number
NCT04194801
Locations
🇨🇳

Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China

🇨🇳

Nanfang Hospital,, Guangzhou, Guangdong, China

🇨🇳

Shanghai East Hospital, Shanghai, Shanghai, China

A Study of Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma

Phase 3
Active, not recruiting
Conditions
Hepatocellular Carcinoma
Interventions
Drug: Nofazinlimab (CS1003)+Lenvatinib
Drug: Nofazinlimab (CS1003) Placebo+Lenvatinib
First Posted Date
2019-12-11
Last Posted Date
2024-07-18
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
534
Registration Number
NCT04194775
Locations
🇨🇳

Nanfang Hospital, Guangzhou, Guangdong, China

🇨🇳

Beijing You'an Hospital, Capital Medical University, Beijing, Beijing, China

🇨🇳

The 900th Hospital of Joint Logistic Support Force of PLA, Fuzhou, Fujian, China

and more 71 locations

A Study of CS1001 in Subjects With Esophageal Squamous Cell Carcinoma

Phase 3
Completed
Conditions
Unresectable Locally Advanced, Recurrent or Metastatic Esophageal Squamous Cell Carcinoma
Interventions
Drug: Placebo+ Fluorouracil+Cisplatin
Drug: CS1001+ Fluorouracil+Cisplatin
First Posted Date
2019-12-05
Last Posted Date
2023-11-24
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
540
Registration Number
NCT04187352
Locations
🇨🇳

Beijing Tsinghua Changgung Hospital, Beijing, Beijing, China

🇨🇳

The First Affiliated Hospital of Henan University of Science and Technology, Luoyang, Henan, China

🇨🇳

Tianjin Medical University General Hospital, Tianjin, Tianjin, China

and more 69 locations

A China Bridging Study of Ivosidenib in r/r AML Subjects With an IDH1 Mutation

Phase 1
Completed
Conditions
Relapsed or Refractory Acute Myeloid Leukemia
Interventions
First Posted Date
2019-11-25
Last Posted Date
2023-02-13
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
30
Registration Number
NCT04176393
Locations
🇨🇳

Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, Tianjin, China

A Study of CS3002 in Subjects With Advanced Solid Tumors

Phase 1
Terminated
Conditions
Advanced Solid Tumor
Interventions
Drug: CS3002
First Posted Date
2019-11-14
Last Posted Date
2021-04-15
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
10
Registration Number
NCT04162301
Locations
🇦🇺

Chris O'Brien Lifehouse, Camperdown, New South Wales, Australia

🇦🇺

Peninsula and South Eastern Haematology and Oncology Group, Heidelberg, Victoria, Australia

A Study of CS1003 in Subjects With Advanced Solid Tumors or Lymphomas

Phase 1
Completed
Conditions
Solid Tumor
Lymphoma
Interventions
Drug: CS1003 monoclonal antibody
First Posted Date
2019-01-18
Last Posted Date
2022-11-30
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
107
Registration Number
NCT03809767
Locations
🇨🇳

Beijing Cancer Hospital, Beijing, China

🇨🇳

Peking Union Medical College Hospital, Beijing, China

🇨🇳

The First Hospital of Jilin University, Changchun, China

and more 14 locations

A Study of CS1001 in Subjects With Gastric Adenocarcinoma or Gastro-Esophageal Junction Adenocarcinoma

Phase 3
Completed
Conditions
Gastric Adenocarcinoma
Gastroesophageal Junction Adenocarcinoma
Interventions
First Posted Date
2019-01-14
Last Posted Date
2023-11-29
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
479
Registration Number
NCT03802591
Locations
🇨🇳

Beijing Cancer Hospital, Beijing, China

A Study of CS1001 in Subjects With Stage IV Non-Small Cell Lung Cancer

Phase 3
Active, not recruiting
Conditions
Non Small Cell Lung Cancer
Interventions
Biological: CS1001 placebo
Biological: CS1001 monoclonal antibody
First Posted Date
2018-12-28
Last Posted Date
2024-08-09
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
479
Registration Number
NCT03789604
Locations
🇨🇳

Shanghai Pulmonary Hospital, Shanghai, Shanghai, China

A Study of CS1001 in Subjects With Advanced Solid Tumors

Phase 1
Completed
Conditions
Advanced Solid Tumors
Interventions
First Posted Date
2018-11-16
Last Posted Date
2022-02-16
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT03744403
Locations
🇺🇸

NEXT Oncology, San Antonio, Texas, United States

Study of CS3006 in Subjects With Locally Advanced or Metastatic Solid Tumors

Phase 1
Completed
Conditions
Locally Advanced or Metastatic Solid Tumors
Interventions
Drug: CS3006
First Posted Date
2018-11-09
Last Posted Date
2021-01-12
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
17
Registration Number
NCT03736850
Locations
🇨🇳

People's Liberation Army 307 Hospital, Beijing, Beijing, China

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