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CSTONE PHARMA-B

🇭🇰Hong Kong, China
Ownership
-
Established
2018-12-13
Employees
164
Market Cap
-
Website
http://www.cstonepharma.com
Introduction

Cornerstone Pharmaceutical was created to meet the needs of cancer patients and focuses on developing and commercializing innovative tumor immunotherapy and molecular-targeted drugs. Since its establishment 3 years ago, the company has assembled a world-class management team with rich experience in preclinical research, clinical development and commercialization.

Through a dual source of innovation consisting of internal R&D and external collaboration, the company has built a powerful anti-tumor drug pipeline with 14 drug candidates, including 4 products exclusively collaborated and authorized by Blueprint Medicine and Agios Pharmaceuticals. Together with the self-developed pipeline, the company has significant potential and synergistic effects for single and combination therapies. Of the drug candidates under development, 4 are in or close to critical trials. Cornerstone Pharmaceutical's business model is driven by clinical research and development, while rapidly establishing commercialization and production capacity.

The company received support from well-known investors, and both the A and B rounds of financing broke records in the biomedical field at the time, with a total amount of 412 million US dollars in the two rounds of financing.

With an experienced team, a promising R&D pipeline, a strong business model, and sustainable financial support, Cornerstone's vision is to become a world-renowned leading Chinese biopharmaceutical company by bringing innovative and differentiated oncology therapies to cancer patients around the world.

Clinical Trials

27

Active:3
Completed:20

Trial Phases

3 Phases

Phase 1:17
Phase 2:3
Phase 3:6

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (26 trials with phase data)• Click on a phase to view related trials

Phase 1
17 (65.4%)
Phase 3
6 (23.1%)
Phase 2
3 (11.5%)

A Phase I Study of CS2009 in Participants With Advanced Solid Tumors

Phase 1
Recruiting
Conditions
Advanced Solid Tumors
Interventions
First Posted Date
2024-12-19
Last Posted Date
2025-03-07
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
230
Registration Number
NCT06741644
Locations
🇦🇺

Alfred Hospital (Alfred Health), Melbourne, Australia

🇦🇺

Austin Hospital (Austin Health), Melbourne, Australia

🇦🇺

Monash Medical Centre (Monash Health), Melbourne, Australia

and more 19 locations

Study of Sugemalimab (or Placebo) Plus PGemOx Regimen in Participants With Extranodal NK/T-Cell Lymphoma

Phase 3
Not yet recruiting
Conditions
Extranodal NK/T-cell Lymphoma
Interventions
First Posted Date
2023-01-26
Last Posted Date
2025-07-08
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
150
Registration Number
NCT05700448

Safety and Efficacy of Avapritinib in Chinese Patients With Gastrointestinal Stromal Tumor (GIST) in the Real World

First Posted Date
2022-05-19
Last Posted Date
2024-11-13
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
61
Registration Number
NCT05381753
Locations
🇨🇳

Beijing Cancer Hospital, Beijing, Beijing, China

A Study of Lorlatinib in Subjects With ROS1-Positive Non-Small Cell Lung Cancer

Phase 2
Active, not recruiting
Conditions
Advanced or Metastatic ROS1-Positive Non-Small Cell Lung Cancer
Interventions
First Posted Date
2022-03-28
Last Posted Date
2025-05-02
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
70
Registration Number
NCT05297890
Locations
🇨🇳

Guangdong Provincial People's hospital, Guangzhou, Guangdong, China

🇨🇳

Beijing Cancer Hospital, Beijing, China

🇨🇳

Cancer Hospital Chinese Academy of Medical Sciences, Beijing, China

and more 28 locations

A Study of CS5001 in Patients With Advanced Solid Tumors and Lymphomas

Phase 1
Recruiting
Conditions
Advanced Solid Tumor
Advanced Lymphoma
Interventions
First Posted Date
2022-03-15
Last Posted Date
2025-04-10
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
156
Registration Number
NCT05279300
Locations
🇦🇺

Central Adelaide Local Health Network Incorporated, Adelaide, South Australia, Australia

🇦🇺

Epworth Foundation trading as Epworth HealthCare, Melbourne, Victoria, Australia

🇨🇳

Anhui Provincial Cancer Hospital, Hefei, Anhui, China

and more 29 locations
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News

CStone Advances CS5001 ROR1-ADC to Phase Ib Trial for First-line DLBCL Treatment

CStone Pharmaceuticals has submitted a Phase Ib clinical trial application in Australia to evaluate CS5001 in combination with R-CHOP as first-line treatment for diffuse large B-cell lymphoma.

ESMO Guidelines Include Sugemalimab as First-Line NSCLC Therapy, Marking Major Treatment Advancement

The European Society for Medical Oncology has incorporated CStone's Cejemly® (sugemalimab) into its NSCLC treatment guidelines, recommending it as a first-line combination therapy for both squamous and non-squamous lung cancer.

ROR1-Targeted Therapies Show Promise in Lymphoma and Solid Tumors

Zilovertamab vedotin combined with R-CHP achieved a 100% complete response rate in untreated diffuse large B-cell lymphoma patients in a Phase 2 trial.

CStone Pharmaceuticals' CS5001 Demonstrates Promising Activity in Advanced Lymphoma

CStone Pharmaceuticals will present clinical data on CS5001, an anti-ROR1 ADC, at the American Society of Hematology Annual Meeting.

MHRA Approves CStone's Sugemalimab (Eqjubi) for First-Line Treatment of NSCLC

The MHRA has approved sugemalimab (Eqjubi) as a first-line combination treatment for metastatic non-small cell lung cancer (NSCLC) in adults.

UK Approves CStone's Sugemalimab (Eqjubi) for First-Line Treatment of NSCLC

The MHRA has granted marketing authorization to sugemalimab (Eqjubi) as a first-line treatment for non-small cell lung cancer (NSCLC) in the UK.

Sugemalimab Approved by MHRA for First-Line Treatment of Metastatic NSCLC

Sugemalimab, in combination with platinum-based chemotherapy, has been approved by the UK's MHRA for first-line treatment of metastatic non-small cell lung cancer (NSCLC).

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