WASHINGTON UNIVERSITY SCHOOL OF MEDICINE

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private, Subsidiary

Established: 1891-01-01

Employees: 10K

Market Cap: -

Website: http://www.medschool.wustl.edu

Clinical Trials

Mechanisms of Action of Dimethyl Fumarate (Tecfidera) in Relapsing MS

Phase 4

Withdrawn

Conditions: Multiple Sclerosis, Relapsing-Remitting
Multiple Sclerosis

Interventions: Drug: Dimethyl Fumarate

First Posted Date: 2016-02-05

Last Posted Date: 2016-07-20

Lead Sponsor: Washington University School of Medicine

Registration Number: NCT02675413

Locations: 🇺🇸
Swedish Neuroscience Institute, Seattle, Washington, United States
🇺🇸
Washington University (John L. Trotter MS Center), St. Louis, Missouri, United States

Thromboelastography Transfusion Protocol for Pediatric Neuromuscular Scoliosis Surgery

Not Applicable

Terminated

Conditions: Neuromuscular Scoliosis

Interventions: Procedure: Thromboelastography laboratory testing

First Posted Date: 2016-02-02

Last Posted Date: 2018-05-03

Lead Sponsor: Washington University School of Medicine

Target Recruit Count: 5

Registration Number: NCT02670798

Locations: 🇺🇸
St. Louis Children's Hospital, Saint Louis, Missouri, United States

MEDI4736 (Durvalumab) in Patients With Brain Metastasis From Epithelial-derived Tumors

Phase 2

Terminated

Conditions: Non-Small Cell Lung Cancer
Nonsmall Cell Lung Cancer
Breast Cancer
Cancer of Breast
Cancer of the Breast
Gastroesophageal Cancer
Pancreatic Cancer
Cancer of the Pancreas
Colorectal Cancer
Colorectal Carcinoma

Interventions: Drug: MEDI4736

First Posted Date: 2016-02-01

Last Posted Date: 2018-11-06

Lead Sponsor: Washington University School of Medicine

Target Recruit Count: 4

Registration Number: NCT02669914

Locations: 🇺🇸
Washington University School of Medicine, Saint Louis, Missouri, United States

Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia

Not Applicable

Completed

Conditions: Type I Arnold-Chiari Malformation
Syringomyelia
Chiari Malformation Type I
Arnold-Chiari Malformation, Type 1

Interventions: Procedure: Dural Augmentation
Procedure: Posterior fossa decompression

First Posted Date: 2016-02-01

Last Posted Date: 2024-10-31

Lead Sponsor: Washington University School of Medicine

Target Recruit Count: 162

Registration Number: NCT02669836

Locations: 🇺🇸
St. Louis Children's Hospital, Saint Louis, Missouri, United States

Mindfulness-Based Stress Reduction, Health Education and Exercise

Not Applicable

Completed

Conditions: Age-related Cognitive Decline

Interventions: Behavioral: MBSR
Behavioral: Health Education
Behavioral: Exercise

First Posted Date: 2016-01-27

Last Posted Date: 2022-09-28

Lead Sponsor: Washington University School of Medicine

Target Recruit Count: 585

Registration Number: NCT02665481

Locations: 🇺🇸
Washington University School of Medicine, Saint Louis, Missouri, United States
🇺🇸
University of California San Diego, San Diego, California, United States

Exercise Training to Improve Brain Health in Older HIV+ Individuals

Not Applicable

Terminated

Conditions: HIV

Interventions: Behavioral: Stretching and Social Interaction
Behavioral: Exercise

First Posted Date: 2016-01-26

Last Posted Date: 2023-11-21

Lead Sponsor: Washington University School of Medicine

Target Recruit Count: 75

Registration Number: NCT02663934

Locations: 🇺🇸
Washington University in St. Louis, Saint Louis, Missouri, United States

Analgesic Efficacy of Liposomal Bupivacaine vs. Bupivacaine HCL as a Tap Block After Abdominally Based Autologous Breast Reconstruction

Phase 4

Terminated

Conditions: Mammaplasty

Interventions: Drug: Liposomal bupivacaine
Drug: Bupivicaine HCL

First Posted Date: 2016-01-25

Last Posted Date: 2019-02-18

Lead Sponsor: Washington University School of Medicine

Target Recruit Count: 70

Registration Number: NCT02662036

Locations: 🇺🇸
Washington University School of Medicine, Saint Louis, Missouri, United States

Bright Light on Fatigue in Women Being Treated for Breast Cancer

Phase 1

Completed

Conditions: Breast Neoplasms
Cancer of Breast
Breast Cancer
Cancer of the Breast

Interventions: Other: Dim red light using light visor cap
Other: Bright blue-green light using light visor cap
Other: European Organization for Research and Treatment of Cancer-Quality of Life Questionnaire
Other: Epworth Sleepiness Scale
Other: Pittsburgh Sleep Quality Index
Other: Patient-Reported Outcomes Measurement Information System (PROMIS)-Sleep Disturbance
Other: Patient-Reported Outcomes Measurement Information System (PROMIS)-Cancer-Fatigue
Diagnostic Test: Digital foot candle datalogging light meter (Extech Instrument, Model SDL400)
Diagnostic Test: Polysomnography (Easy Ambulatory 2 Cadwell, Kennewick, WA)
Other: Horne-Ostberg Morningness-Eveningness Questionnaire
Other: Daily Fatigue and Sleep Log

First Posted Date: 2016-01-20

Last Posted Date: 2017-09-25

Lead Sponsor: Washington University School of Medicine

Target Recruit Count: 19

Registration Number: NCT02658708

Locations: 🇺🇸
Washington University School of Medicine, Saint Louis, Missouri, United States

Reducing Readmissions in High-Risk Ostomates

Not Applicable

Terminated

Conditions: Ileostomy

Interventions: Other: Pre-operative education (standard of care)
Other: Home health care visits (standard of care)
Other: Follow-up post-operative visits
Other: Patient Data Collection Form
Other: Healthcare Utilization Form
Other: The City of Hope QOL Survey for Ostomy Patients
Other: Phone call with CWOCN or PA

First Posted Date: 2016-01-18

Last Posted Date: 2018-10-01

Lead Sponsor: Washington University School of Medicine

Target Recruit Count: 94

Registration Number: NCT02658123

Locations: 🇺🇸
Washington University School of Medicine, Saint Louis, Missouri, United States

Ibrutinib as Neoadjuvant Therapy in Localized Prostate Cancer

Phase 2

Completed

Conditions: Prostate Cancer

Interventions: Drug: Ibrutinib
Procedure: Radical prostatectomy

First Posted Date: 2015-12-31

Last Posted Date: 2025-01-08

Lead Sponsor: Washington University School of Medicine

Target Recruit Count: 27

Registration Number: NCT02643667

Locations: 🇺🇸
University of California, San Francisco, San Francisco, California, United States
🇺🇸
Washington University School of Medicine, Saint Louis, Missouri, United States

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