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Acumen Pharmaceuticals

Acumen Pharmaceuticals logo
🇺🇸United States
Ownership
Public
Established
1996-01-01
Employees
52
Market Cap
$168.8M
Website
http://www.acumenpharm.com
Introduction

Acumen Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company, which discovers and develops medicines and diagnostics for Alzheimer's disease. The company was founded by William L. Klein, Grant A. Krafft, and Caleb Finch in 1996 and is headquartered in Charlottesville, VA.

Clinical Trials

4

Active:2
Completed:2

Trial Phases

2 Phases

Phase 1:3
Phase 2:1

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (4 trials with phase data)• Click on a phase to view related trials

Phase 1
3 (75.0%)
Phase 2
1 (25.0%)

A Study Comparing the Safety, Tolerability, and Pharmacokinetics of Sabirnetug IV and Sabirnetug + rHuPH20 SC in Healthy Participants

Phase 1
Completed
Conditions
Alzheimer Disease
Interventions
Drug: sabirnetug (ACU193)
Combination Product: Sabirnetug + rHuPH20
First Posted Date
2024-07-22
Last Posted Date
2024-10-18
Lead Sponsor
Acumen Pharmaceuticals
Target Recruit Count
28
Registration Number
NCT06511570
Locations
🇺🇸

Worldwide Clinical Trials, San Antonio, Texas, United States

A Study to Evaluate Efficacy and Safety of Intravenous Sabirnetug in Participants With Early Alzheimer's Disease (ALTITUDE-AD)

Phase 2
Active, not recruiting
Conditions
Alzheimer Disease
Interventions
Drug: Placebo
First Posted Date
2024-03-28
Last Posted Date
2025-08-01
Lead Sponsor
Acumen Pharmaceuticals
Target Recruit Count
540
Registration Number
NCT06335173
Locations
🇺🇸

The Neurology Center of Southern California - Carlsbad, Carlsbad, California, United States

🇺🇸

Neurology Center of North Orange County, Fullerton, California, United States

🇺🇸

Irvine Medical Research, Irvine, California, United States

and more 66 locations

A Study to Evaluate the Safety, Tolerability, and Blood Levels of ACU193 in Participants With MCI or Mild AD

Phase 1
Completed
Conditions
Alzheimer Disease
Interventions
Drug: Placebo
First Posted Date
2021-06-18
Last Posted Date
2023-07-19
Lead Sponsor
Acumen Pharmaceuticals
Target Recruit Count
65
Registration Number
NCT04931459
Locations
🇺🇸

Clinical Endpoints, Scottsdale, Arizona, United States

🇺🇸

Orange County Research Institute, Anaheim, California, United States

🇺🇸

Hoag Hospital Newport Beach, Newport Beach, California, United States

and more 14 locations

News

Acumen Pharmaceuticals Partners with JCR to Develop Enhanced Brain Delivery Therapy for Alzheimer's Disease

Acumen Pharmaceuticals and JCR Pharmaceuticals have entered a strategic collaboration to combine Acumen's amyloid beta oligomer-selective antibody expertise with JCR's blood-brain barrier-penetrating J-Brain Cargo® technology for Alzheimer's disease treatment.

Biogen and Acumen Advance Alzheimer's Research with Long-Term Data and Novel Targeting Approaches at AAIC 2025

Biogen presents 48-month data from LEQEMBI's Clarity AD open-label extension study and introduces subcutaneous formulation for maintenance dosing at AAIC 2025.

ALS Drug NU-9 Shows Promising Results for Alzheimer's Disease in Animal Study

Northwestern University researchers found that NU-9, an experimental drug approved for ALS clinical trials, effectively reduces toxic protein buildup in Alzheimer's disease animal models.

Acumen Pharmaceuticals Advances Sabirnetug for Alzheimer's, Reports Q3 2024 Financials

Acumen Pharmaceuticals is progressing its Phase 2 ALTITUDE-AD trial of sabirnetug, an immunotherapy for Alzheimer's, with enrollment expected to complete in H1 2025.

Acumen Pharmaceuticals' pTau217 Assay Streamlines Alzheimer's Clinical Trials

Acumen Pharmaceuticals presents data on pTau217 assay for efficient screening in the ALTITUDE-AD trial, reducing the need for invasive procedures.

Acumen Pharmaceuticals Utilizes pTau217 Assay in Sabirnetug Phase 2 Alzheimer's Trial

Acumen Pharmaceuticals is using a validated plasma pTau217 assay to screen participants for its Phase 2 ALTITUDE-AD trial of sabirnetug in early Alzheimer's disease.

Acumen and NKGen Present Alzheimer's Research at CTAD 2024

Acumen Pharmaceuticals will present data on using plasma pTau217 assay for screening participants in their Phase 2 ALTITUDE-AD trial.

Acumen and Lonza Expand Collaboration to Advance Sabirnetug for Alzheimer's Disease

Acumen Pharmaceuticals and Lonza have broadened their partnership to include drug product manufacturing for sabirnetug, targeting early Alzheimer's disease.

Acumen Pharmaceuticals Advances Sabirnetug in Alzheimer's Disease Treatment

Acumen Pharmaceuticals is developing sabirnetug (ACU193), a monoclonal antibody targeting toxic amyloid-beta oligomers, a primary cause of Alzheimer's disease.

Pharmaceutical Industry Leadership Shuffle: Major Executive Appointments Signal Strategic Shifts Across Biotech and Pharma

AbbVie promoted long-time COO Robert Michael to CEO, marking the end of an extensive leadership search with an internal succession plan.

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