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Vor Biopharma

🇺🇸United States
Ownership
-
Employees
168
Market Cap
$60.8M
Website
Introduction

Vor Biopharma, Inc. engages in developing cell therapies for treating cancer. It is a clinical-stage cell therapy company that combines a novel patient engineering approach with therapies to provide a single company solution for patients suffering from hematological malignancies. The company was founded by Aleks Radovic-Moreno and Siddhartha Mukherjee on December 30, 2015 and is headquartered in Cambridge, MA.

Clinical Trials

3

Active:0
Completed:0

Trial Phases

1 Phases

Phase 1:2

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (2 trials with phase data)• Click on a phase to view related trials

Phase 1
2 (100.0%)

Donor-Derived Anti-CD33 CAR T Cell Therapy (VCAR33) in Patients With Relapsed or Refractory AML After Allogeneic Hematopoietic Cell Transplant

Phase 1
Terminated
Conditions
Leukemia, Myeloid, Acute
Interventions
First Posted Date
2023-08-09
Last Posted Date
2025-07-29
Lead Sponsor
Vor Biopharma
Target Recruit Count
38
Registration Number
NCT05984199
Locations
🇺🇸

University of California San Diego Moores Cancer Center, La Jolla, California, United States

🇺🇸

Stanford Cancer Institute, Stanford, California, United States

🇺🇸

Miami Cancer Institute, Miami, Florida, United States

and more 11 locations

A Long-term Follow-up Study of Patients Who Received VOR33

Terminated
Conditions
Leukemia, Myeloid, Acute
First Posted Date
2022-04-04
Last Posted Date
2025-07-29
Lead Sponsor
Vor Biopharma
Target Recruit Count
10
Registration Number
NCT05309733
Locations
🇺🇸

University of California San Diego Moores Cancer Center, La Jolla, California, United States

🇺🇸

Miami Cancer Institute, Miami, Florida, United States

🇺🇸

National Institutes of Health, Clinical Center, Bethesda, Maryland, United States

and more 8 locations

Allogeneic Engineered Hematopoietic Stem Cell Transplant (HCT) Lacking the CD33 Protein, and Post-HCT Treatment With Mylotarg, for Patients With CD33+ AML or MDS

Phase 1
Terminated
Conditions
Leukemia, Myeloid, Acute
Myelodysplastic Syndromes
Interventions
First Posted Date
2021-04-19
Last Posted Date
2025-07-29
Lead Sponsor
Vor Biopharma
Target Recruit Count
67
Registration Number
NCT04849910
Locations
🇺🇸

University of California San Diego Moores Cancer Center, La Jolla, California, United States

🇺🇸

Stanford Cancer Institute, Stanford, California, United States

🇺🇸

Miami Cancer Institute, Miami, Florida, United States

and more 12 locations

News

Vor Biopharma Announces Positive Data and New CD45 ADC Program, Analysts See Significant Upside

• Vor Biopharma reported updated Phase 1/2 VBP101 study results showing promising relapse-free survival data in AML/MDS patients, exceeding historical benchmarks. • Initial PK data for VCAR33ALLO demonstrated in vivo expansion at the lowest dose, with dose escalation planned, indicating potential efficacy. • The company is developing a new CD45 ADC program (VADC45) for conditioning regimens, offering a fast path to commercial development and partnership opportunities. • Analysts maintain an Outperform rating with a price target of US$11.00, citing significant upside potential from trem-cel and CD45-based depletion approaches.

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