MedPath

Coherus BioSciences

Coherus BioSciences logo
🇺🇸United States
Ownership
Public
Established
2010-01-01
Employees
306
Market Cap
$160.1M
Website
http://www.coherus.com
Introduction

Coherus BioSciences, Inc. is a commercial-stage biopharmaceutical company, which engages in the development and commercialization of biosimilar therapeutics. Its products include UDENYCA and Coherus COMPLETE. The company was founded by Dennis M. Lanfear, Stuart E. Builder, Dr. Alan Herman, Doug Farrar and Steve Glover in September 2010 and is headquartered in Redwood City, CA.

Clinical Trials

28

Active:11
Completed:8

Trial Phases

4 Phases

Phase 1:19
Phase 2:3
Phase 3:4
+1 more phases

Drug Approvals

4

FDA:4

Drug Approvals

UDENYCA

Approval Date
Dec 22, 2023
FDA

LOQTORZI

Approval Date
Nov 27, 2023
FDA

YUSIMRY

Approval Date
Sep 30, 2023
FDA

CIMERLI

Approval Date
Nov 1, 2022
FDA

Clinical Trials

Distribution across different clinical trial phases (27 trials with phase data)• Click on a phase to view related trials

Phase 1
19 (70.4%)
Phase 3
4 (14.8%)
Phase 2
3 (11.1%)
Phase 4
1 (3.7%)

A Trial of Casdozokitug in Combination With Toripalimab Plus Bevacizumab in Participants With Unresectable and/or Locally Advanced or Metastatic Hepatocellular Carcinoma

Phase 2
Recruiting
Conditions
Hepatocellular Carcinoma
Interventions
First Posted Date
2024-11-08
Last Posted Date
2025-07-11
Lead Sponsor
Coherus Biosciences, Inc.
Target Recruit Count
72
Registration Number
NCT06679985
Locations
🇺🇸

The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solovev Research Institute (OSUCCC - James), Columbus, Ohio, United States

🇺🇸

Beverly Hills Cancer Center, Beverly Hills, California, United States

🇺🇸

City of Hope, Duarte, California, United States

and more 12 locations

A Study of CHS-114 in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

Phase 1
Recruiting
Conditions
Metastatic Solid Tumor
Advanced Solid Tumor
Interventions
First Posted Date
2024-10-24
Last Posted Date
2025-07-11
Lead Sponsor
Coherus Biosciences, Inc.
Target Recruit Count
72
Registration Number
NCT06657144
Locations
🇺🇸

The University of Arizona Cancer Center, Tucson, Arizona, United States

🇺🇸

Ochsner Health, New Orleans, Louisiana, United States

🇺🇸

Prisma Health Cancer Institute, Greenville, South Carolina, United States

and more 5 locations

A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer

Phase 4
Recruiting
Conditions
Nasopharyngeal Cancer Recurrent
Interventions
First Posted Date
2024-06-13
Last Posted Date
2025-06-13
Lead Sponsor
Coherus Biosciences, Inc.
Target Recruit Count
100
Registration Number
NCT06457503
Locations
🇺🇸

University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

🇺🇸

University of California, Irvine, Irvine, California, United States

🇺🇸

University of California, San Francisco, San Francisco, California, United States

and more 7 locations

A Study of CHS-1000 in Participants With Advanced or Metastatic Solid Tumors

Phase 1
Not yet recruiting
Conditions
Advanced or Metastatic Solid Tumors
Interventions
First Posted Date
2024-04-29
Last Posted Date
2024-04-29
Lead Sponsor
Coherus Biosciences, Inc.
Target Recruit Count
48
Registration Number
NCT06389526

Study to Evaluate Safety and PK of CHS-006 in Combination With Toripalimab in Patients With Advanced Solid Tumors

Phase 1
Terminated
Conditions
Advanced Solid Tumor
Non-Small Cell Lung Cancer
Hepatocellular Carcinoma
Interventions
Drug: CHS-006 (anti-TIGIT)
First Posted Date
2023-03-07
Last Posted Date
2025-05-01
Lead Sponsor
Coherus Biosciences, Inc.
Target Recruit Count
22
Registration Number
NCT05757492
Locations
🇺🇸

University of Florida Health Cancer Center, Orlando, Florida, United States

🇺🇸

Barbara Ann Karmanos Cancer Institute, Detroit, Michigan, United States

🇺🇸

Renown Institute for Cancer, Reno, Nevada, United States

and more 1 locations
  • Prev
  • 1
  • 2
  • 3
  • 4
  • Next

News

STORM Therapeutics Initiates First-in-Class RNA Modification Therapy Combination Trial with Checkpoint Inhibitor

STORM Therapeutics has dosed the first patient in a Phase 1b/2 combination study evaluating STC-15, a METTL3 inhibitor, with LOQTORZI (toripalimab) for multiple cancer types.

Coherus BioSciences Completes $558.4 Million UDENYCA Divestiture to Intas, Pivots to Oncology Focus

Coherus BioSciences has completed the divestiture of its UDENYCA pegfilgrastim franchise to Intas Pharmaceuticals in a deal valued at up to $558.4 million, receiving $483.4 million upfront with potential for $75 million in milestone payments.

Coherus Reports Promising Phase 1 Data for CHS-114 in Head and Neck Cancer, Showing Potential to Overcome PD-1 Resistance

Coherus BioSciences' selective anti-CCR8 antibody CHS-114 demonstrated clinical efficacy in combination with toripalimab in head and neck squamous cell carcinoma, achieving a confirmed partial response in a heavily pretreated PD-1 refractory patient.

FDA Delays Toripalimab Review for Nasopharyngeal Carcinoma Due to Pending Manufacturing Site Inspection

The FDA has not issued an action letter for toripalimab's Biologics License Application by the December 23, 2022 PDUFA date, pending required manufacturing facility inspection in China.

FDA Tightens Requirements for China-Developed Drugs, Mandates Multi-Regional Trials

The FDA has rejected multiple China-developed drugs, including Hutchmed's surufatinib and Eli Lilly's sintilimab, citing concerns over single-country clinical trial data.

Coherus BioSciences' Liver Cancer Triplet Therapy Shows Promise in Phase 2 Study

Coherus BioSciences' novel triplet therapy combining casdozo, atezolizumab, and bevacizumab demonstrates significant efficacy in treating metastatic hepatocellular carcinoma during Phase 2 trials.

INOVIO Advances DNA Medicine Pipeline with Focus on INO-3107 BLA Submission for RRP

INOVIO plans to submit a Biologics License Application (BLA) to the FDA for INO-3107 by mid-2025, seeking priority review for recurrent respiratory papillomatosis.

Coherus' Casdozokitug Shows Promising Results in Liver Cancer Phase 2 Trial

Coherus BioSciences presented final Phase 2 data for casdozokitug combined with atezolizumab and bevacizumab in patients with unresectable or metastatic hepatocellular carcinoma.

Global Biosimilars Market Set to Triple to $114 Billion by 2031, Driven by Patent Expirations and Cost Advantages

The global biosimilars market is projected to grow from $36.01 billion in 2024 to $114.02 billion by 2031, representing a robust CAGR of 17.9%, fueled by increasing demand for cost-effective biologics.

China's Biopharmaceutical Sector Achieves Record Technology Exports and FDA Approvals

• Chinese pharmaceutical companies saw technology exports nearly double in 2023, reaching a record high of 80 cases, signaling growing global influence. • FDA approved Junshi Biosciences' Toripalimab for nasopharyngeal cancer and Bio-Thera Solutions' Avitinib, highlighting recognition of Chinese therapies. • Multinational firms like Merck and Johnson & Johnson have invested billions in Chinese biotech, developing drugs like Carvykti for multiple myeloma. • China leads in CAR-T clinical trials, accounting for 51% globally, but Korean bio companies face stagnation in technology export amounts.

© Copyright 2025. All Rights Reserved by MedPath