Protara Therapeutics
- Country
- 🇺🇸United States
- Ownership
- Public
- Established
- 2017-01-01
- Employees
- 27
- Market Cap
- $42.4M
- Website
- http://www.protaratx.com
- Introduction
Protara Therapeutics, Inc. is a clinical-stage company engaged in developing treatments for rare and specialty diseases with significant unmet needs. Its current development programs focus on the treatment of rare diseases in structural and connective tissues and rare hepatology, gastrointestinal, and metabolic disorders. The company was founded by Jesse Shefferman and Jacqueline Zummo in March 2006 and is headquartered in New York, NY.
Clinical Trials
7
Trial Phases
2 Phases
Drug Approvals
0
Drug Approvals
No drug approvals found
This company may not have drug approvals in our database
Clinical Trials
Distribution across different clinical trial phases (5 trials with phase data)• Click on a phase to view related trials
Study of Choline Chloride for Injection in Adolescent and Adult Patients With Intestinal Failure Receiving Long Term Parenteral Support
- Conditions
- Choline DeficiencyLiver Injury
- Interventions
- Drug: Choline Chloride for InjectionDrug: Placebo
- First Posted Date
- 2025-04-04
- Last Posted Date
- 2025-04-04
- Lead Sponsor
- Protara Therapeutics
- Target Recruit Count
- 144
- Registration Number
- NCT06910943
Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer
- First Posted Date
- 2023-07-18
- Last Posted Date
- 2025-04-29
- Lead Sponsor
- Protara Therapeutics
- Target Recruit Count
- 127
- Registration Number
- NCT05951179
- Locations
- 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States
🇺🇸Urology Group of Southern California, Los Angeles, California, United States
🇺🇸University of California Irvine Medical Center, Orange, California, United States
Safety and Efficacy Study of Intracystic TARA-002 for the Treatment of Lymphatic Malformations in Participants 6 Months to Less Than 18 Years of Age
- First Posted Date
- 2023-05-23
- Last Posted Date
- 2024-12-27
- Lead Sponsor
- Protara Therapeutics
- Target Recruit Count
- 38
- Registration Number
- NCT05871970
- Locations
- 🇺🇸
Oregon Health & Science University, Portland, Oregon, United States
🇺🇸Children's Hospital of Alabama, Birmingham, Alabama, United States
🇺🇸Arkansas Children's Hospital/UAMS, Little Rock, Arkansas, United States
Safety and Toxicity Study of Intravesical Instillation of TARA-002 in Adults with High-grade Non-muscle Invasive Bladder Cancer (Phase 1b)
- First Posted Date
- 2021-10-20
- Last Posted Date
- 2025-01-27
- Lead Sponsor
- Protara Therapeutics
- Target Recruit Count
- 10
- Registration Number
- NCT05085990
- Locations
- 🇺🇸
USC Norris Cancer Center, Los Angeles, California, United States
🇺🇸Mayo Clinic, Rochester, Minnesota, United States
🇺🇸Tulane Medical Center (TMC) - Clinic/Outpatient Facility, New Orleans, Louisiana, United States
Safety and Toxicity Study of Intravesical Instillation of TARA-002 in Adults with High-grade Non-muscle Invasive Bladder Cancer (Phase 1a)
- First Posted Date
- 2021-10-20
- Last Posted Date
- 2025-01-27
- Lead Sponsor
- Protara Therapeutics
- Target Recruit Count
- 12
- Registration Number
- NCT05085977
- Locations
- 🇺🇸
USC Norris Cancer Center, Los Angeles, California, United States
🇺🇸Mayo Clinic, Rochester, Minnesota, United States
🇺🇸Tulane Medical Center, New Orleans, Louisiana, United States
- Prev
- 1
- 2
- Next
News
Protara Therapeutics Appoints William Conkling as Chief Commercial Officer to Lead Commercialization Strategy
Protara Therapeutics has appointed William Conkling as Chief Commercial Officer, bringing over two decades of experience in developing and commercializing cancer and rare disease therapeutics.
Biotech Leadership Shuffle Continues as Industry Navigates Transformation in Q2 2025
Novo Nordisk undergoes significant executive restructuring following the departure of EVP Camilla Sylvest, with rare disease leader Ludovic Helfgott taking over expanded commercial strategy responsibilities.
Protara Therapeutics Reports 72% Complete Response Rate in NMIBC Trial, Secures $100M Funding
Protara Therapeutics' TARA-002 demonstrates strong efficacy in Phase 2 ADVANCED-2 trial for non-muscle invasive bladder cancer, achieving 72% six-month complete response rate across all BCG exposure levels.
Protara Therapeutics Announces Key Milestones for 2025, Including NMIBC and LM Data
Protara Therapeutics anticipates mid-2025 data from the ADVANCED-2 trial of TARA-002 in non-muscle invasive bladder cancer (NMIBC) patients, building on positive six-month results.
TARA-002 and Cretostimogene Grenadenorepvec Show Promise in Bladder Cancer
• Protara Therapeutics' TARA-002 demonstrated a 72% complete response rate in non-muscle invasive bladder cancer patients, regardless of prior BCG exposure. • In BCG-unresponsive patients, TARA-002 achieved a 100% complete response rate at six months, highlighting its potential in a registrational cohort. • CG Oncology's cretostimogene grenadenorepvec showed a 74.5% complete response rate in BCG-unresponsive patients, with a median duration of response exceeding 27 months. • Both TARA-002 and cretostimogene grenadenorepvec exhibited favorable tolerability profiles, with minimal treatment-related adverse events.
Protara's TARA-002 Shows Promise in Phase 2 Trial for Bladder Cancer
Protara Therapeutics' TARA-002 demonstrated a 72% six-month complete response rate in NMIBC patients across various BCG exposure statuses.
Protara Therapeutics Presents Promising Interim Data on TARA-002 for Bladder Cancer
Protara Therapeutics is presenting interim Phase 2 data for TARA-002 in non-muscle invasive bladder cancer (NMIBC) at the SUO annual meeting.
Protara Therapeutics Announces Progress in TARA-002 and IV Choline Chloride Programs
Protara Therapeutics' TARA-002 shows promise in NMIBC treatment, with ADVANCED-2 trial results expected in Q4 2024, and positive interim data in Lymphatic Malformations.
Protara Therapeutics Receives FDA Fast Track Designation for IV Choline Chloride
Protara Therapeutics' IV Choline Chloride receives FDA Fast Track designation for treating choline deficiency in parenteral support patients.