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Alzheon, Inc.

Alzheon, Inc. logo
🇺🇸United States
Ownership
Holding
Established
2013-06-01
Employees
11
Market Cap
-
Website
http://www.alzheon.com

Clinical Trials

15

Active:10
Completed:3

Trial Phases

3 Phases

Phase 1:10
Phase 2:2
Phase 3:3

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (15 trials with phase data)• Click on a phase to view related trials

Phase 1
10 (66.7%)
Phase 3
3 (20.0%)
Phase 2
2 (13.3%)

Long-term Extension of Phase 3 Study of ALZ- 801 in APOE4/4 Early AD Subjects

Phase 3
Active, not recruiting
Conditions
Early Alzheimer's Disease
First Posted Date
2024-03-12
Last Posted Date
2025-07-08
Lead Sponsor
Alzheon Inc.
Target Recruit Count
163
Registration Number
NCT06304883
Locations
🇺🇸

Xenoscience, Inc., Phoenix, Arizona, United States

🇺🇸

Banner Sun Health Research Institute, Sun City, Arizona, United States

🇺🇸

ATP Clinical Research, Costa Mesa, California, United States

and more 37 locations

An Efficacy and Safety Study of ALZ-801 in APOE4/4 Early AD Subjects

Phase 3
Completed
Conditions
Early Alzheimer's Disease
First Posted Date
2021-02-25
Last Posted Date
2025-05-16
Lead Sponsor
Alzheon Inc.
Target Recruit Count
325
Registration Number
NCT04770220
Locations
🇺🇸

Tilda Research, Irvine, California, United States

🇺🇸

Sandhill Research, LLC, Decatur, Georgia, United States

🇺🇸

WR-CRCN, Las Vegas, Nevada, United States

and more 88 locations

Biomarker Effects of ALZ-801 in APOE4 Carriers With Early Alzheimer's Disease

Phase 2
Active, not recruiting
Conditions
Early Alzheimer's Disease
Interventions
First Posted Date
2021-01-05
Last Posted Date
2024-02-01
Lead Sponsor
Alzheon Inc.
Target Recruit Count
84
Registration Number
NCT04693520
Locations
🇨🇿

St. Anne's University Hospital, Brno, Czechia

🇨🇿

Motol University Hospital, Prague, Czechia

🇨🇿

Vestra Clinics, Rychnov Nad Kněžnou, Czechia

and more 1 locations

Single Dose Study of ALZ-801 Prototype Tablets

Phase 1
Completed
Conditions
Alzheimer Disease
Interventions
Drug: ALZ-801 205 mg After Food
Drug: ALZ-801 170 mg Fasting
Drug: ALZ-801 205 mg Fasting
Drug: ALZ-801 342 mg Fasting
First Posted Date
2020-10-14
Last Posted Date
2020-10-14
Lead Sponsor
Alzheon Inc.
Target Recruit Count
12
Registration Number
NCT04585347

Multiple Ascending Dose Study of ALZ-801

Phase 1
Completed
Conditions
Alzheimer Disease
Interventions
Drug: ALZ-801 or matching placebo
First Posted Date
2019-11-08
Last Posted Date
2019-11-19
Lead Sponsor
Alzheon Inc.
Target Recruit Count
48
Registration Number
NCT04157712
Locations
🇬🇧

Quotient Clinical, Ruddington, Nottingham, United Kingdom

News

Voyager Therapeutics Advances Novel APOE4 Gene Therapy for Alzheimer's Disease Using IV-Delivered TRACER Platform

Voyager Therapeutics has launched a new gene therapy program targeting APOE4, the strongest genetic risk factor for Alzheimer's disease, using its proprietary TRACER capsid technology for intravenous delivery.

Alzheimer's Drug Pipeline Shows Promising Diversity as 88 Trials Recruit Patients in 2025

The Alzheimer's drug development landscape has expanded significantly beyond anti-amyloid antibodies, with 88 different clinical trials currently recruiting patients and twelve Phase 3 trials expected to report results in 2025.

Alzheon's Valiltramiprosate Shows Promising Results for Early-Stage Alzheimer's in APOE4 Homozygotes

Phase 3 APOLLOE4 trial results reveal valiltramiprosate (ALZ-801) demonstrated significant benefits in patients with mild cognitive impairment, showing 52% improvement on ADAS-Cog13 and 102% improvement on CDR-SB scales.

Alzheon to Present Phase 3 Data for ALZ-801, Aiming to Slow Alzheimer's Progression

Alzheon is set to present Phase 3 trial data for ALZ-801 in April 2025, a drug designed to prevent the formation of toxic beta-amyloid plaques in early Alzheimer's patients with the ApoE4 gene.

Alzheon's ALZ-801 Shows Promise in Reducing Phosphorylated Tau and Enhancing Memory in Early Alzheimer's Disease

Alzheon's ALZ-801 demonstrated a 29% reduction in plasma p-tau181 levels at 26 weeks in patients with early Alzheimer's, indicating a potential disease-modifying effect.

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