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Merck, Inc.

Merck, Inc. logo
🇺🇸United States
Ownership
Subsidiary
Employees
-
Market Cap
$295.3B
Website
http://www.merck.ph

Imipenem/Cilastatin/Relebactam (MK-7655A) Versus Piperacillin/Tazobactam in Participants With Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia (MK-7655A-016)

Phase 3
Completed
Conditions
Hospital-Acquired Bacterial Pneumonia
Ventilator-Associated Bacterial Pneumonia
Interventions
Drug: IMI/REL FDC
Drug: PIP/TAZ FDC
First Posted Date
2018-07-11
Last Posted Date
2025-01-29
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
274
Registration Number
NCT03583333
Locations
🇨🇳

Peking University First Hospital ( Site 0131), Beijing, Beijing, China

🇨🇳

Zhongshan Hospital Affiliated to Xiamen University ( Site 0133), Xiamen, Fujian, China

🇨🇳

The Seventh Medical Center of PLA General Hospital-Intensive medicine ( Site 0157), Beijing, Beijing, China

and more 65 locations

Study of Gefapixant (MK-7264) in Acute Cough for Participants With Induced Viral Upper Respiratory Tract Infection (URTI) (MK-7264-013)

Phase 2
Terminated
Conditions
Acute Cough
Interventions
Drug: Placebo
First Posted Date
2018-06-26
Last Posted Date
2019-12-10
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
46
Registration Number
NCT03569033
Locations
🇬🇧

Hvivo Service Limited. Queen Mary BioEnterprises ( Site 0003), London, United Kingdom

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 in Allogeneic Hematopoietic Stem Cell Transplant Recipients (V114-022/PNEU-STEM)

Phase 3
Completed
Conditions
Pneumococcal Infections
Interventions
Biological: Prevnar 13™
Biological: V114
Biological: PNEUMOVAX™23
First Posted Date
2018-06-21
Last Posted Date
2023-07-28
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
277
Registration Number
NCT03565900
Locations
🇦🇺

St. Vincent's Hospital ( Site 0041), Sydney, New South Wales, Australia

🇧🇷

Hospital Sao Rafael ( Site 0049), Salvador, Bahia, Brazil

🇺🇸

Baylor College of Medicine - Texas Children's Hospital ( Site 0165), Houston, Texas, United States

and more 49 locations

A Safety, Tolerability, and Pharmacokinetics Study of MK-8189 in Participants With Schizophrenia and in Healthy Participants (MK-8189-007)

Phase 1
Completed
Conditions
Schizophrenia
Interventions
Drug: Placebo
Drug: Background AAP Therapy
First Posted Date
2018-06-21
Last Posted Date
2021-03-29
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
75
Registration Number
NCT03565068
Locations
🇺🇸

California Clinical Trials ( Site 0001), Glendale, California, United States

Study of MK-4830 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-4830-001)

First Posted Date
2018-06-21
Last Posted Date
2024-11-27
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
442
Registration Number
NCT03564691
Locations
🇨🇦

Princess Margaret Cancer Centre ( Site 0033), Toronto, Ontario, Canada

🇺🇸

Seattle Cancer Care Alliance ( Site 0010), Seattle, Washington, United States

🇺🇸

University of California at San Francisco ( Site 0004), San Francisco, California, United States

and more 34 locations

Safety and Efficacy of Pembrolizumab Compared to Placebo in Resected High-risk Stage II Melanoma (MK-3475-716/KEYNOTE-716)

Phase 3
Active, not recruiting
Conditions
Melanoma
Interventions
First Posted Date
2018-06-12
Last Posted Date
2024-11-28
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
976
Registration Number
NCT03553836
Locations
🇺🇸

The Angeles Clinic and Research Institute ( Site 0029), Los Angeles, California, United States

🇺🇸

Winship Cancer Institute of Emory University ( Site 0046), Atlanta, Georgia, United States

🇺🇸

UCLA Hematology & Oncology ( Site 0130), Los Angeles, California, United States

and more 156 locations

MK-8583 Single Dose Study in Human Immunodeficiency Virus Type 1 (HIV-1) Infected Participants (MK-8583-002)

Phase 1
Completed
Conditions
HIV-1 Infection
Interventions
First Posted Date
2018-06-12
Last Posted Date
2020-03-04
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
5
Registration Number
NCT03552536
Locations
🇩🇪

Charite Research Organisation GmbH ( Site 0001), Berlin, Germany

SCH 54031 PEG12000 Interferon Alfa-2b (PEG Intron, MK-4031) vs. INTRON®A (SCH 30500, MK-2958) as Adjuvant Therapy for Melanoma (C98-135, MK-4031-002)

Phase 2
Terminated
Conditions
Melanoma
Interventions
Biological: INTRON A
Biological: PEG-Intron
First Posted Date
2018-06-12
Last Posted Date
2019-07-24
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
126
Registration Number
NCT03552549

Extended Administration of Polyethylene Glycol (PEG) Interferon Alfa-2b in Participants With Solid Tumors (C/I97-349/MK-4031-009)

Phase 1
Completed
Conditions
Neoplasms
Interventions
First Posted Date
2018-06-12
Last Posted Date
2019-07-15
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
29
Registration Number
NCT03554005

Polyethylene Glycol Interferon Alfa-2b (PEG Intron) Versus Interferon Alfa-2b (INTRON^® A) in the Treatment of Newly Diagnosed Chronic Myelogenous Leukemia (CML) (C98026)

Phase 2
Terminated
Conditions
Chronic Myelogenous Leukemia
Interventions
Biological: Interferon alfa-2b
Biological: Pegylated interferon alfa-2b
First Posted Date
2018-06-06
Last Posted Date
2019-08-12
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
344
Registration Number
NCT03547154
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