Indiana University School Of Medicine

RPLND for stage II seminoma shows 70-90% 2-year RFS in trials, prompting AUA/NCCN guideline updates. Recurrences mostly occur within 2 years, with effective salvage chemotherapy. Lymph node mapping suggests higher crossover rates in seminoma vs. NSGCTs. Complications are mild, with 4.5% rate at IU. RPLND is a safe, effective option for early stage II seminoma.

Indiana University School of Medicine's diversity among new medical students dropped from 24% to 8.8% in 2024, attributed to the U.S. Supreme Court's decision barring diversity considerations in admissions. The school aims to improve diversity by raising awareness and creating pathways for underrepresented students in healthcare.

NIH awards $27M to establish a Genomics-enabled Learning Health System (gLHS) Network, aiming to integrate genomic information into patient care. The network includes six clinical sites and a coordinating center, focusing on developing and refining genomic medicine practices. The initiative seeks to create generalizable knowledge and tools for broader patient care, including under-resourced settings.

The National Institute on Aging awards $15.5 million to a team led by Cari Levy, MD, PhD, to increase nursing home residents' participation in clinical trials through the NEXT STEPs project. The initiative aims to build a research infrastructure, focusing on recruitment, methods, and training, to better understand and improve care for the elderly.

Study uses three cohorts (discovery, validation, testing) to discover, prioritize, validate, and test biomarkers for suicidality, integrating microarray and RNA sequencing data. Key steps include discovery of biomarkers tracking suicidality, prioritization through Convergent Functional Genomics, validation in postmortem suicide completers, and testing in independent psychiatric cohorts for predicting suicidality severity and future hospitalizations. Top candidate biomarkers are identified and tested for clinical utility, with a focus on gender-specific predictions and personalized medicine.

Andrew A. Gonzalez, M.D., J.D., MPH, of the Regenstrief Institute and Indiana University School of Medicine, co-edited a draft Code of Conduct for AI use in healthcare, aiming to ensure AI's reliable and safe revolutionization of healthcare. The code, developed by the National Academy of Medicine, outlines 10 principles and 6 commitments to maximize AI's benefits while minimizing risks, focusing on equity, accuracy, and safety.

NIH grants $15.5m to establish NEXT STEPs network to include nursing home residents in clinical trials, led by Dr Kathleen Unroe, aiming to address their underrepresentation and enhance care quality.