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Cellectar BioSciences

🇺🇸United States
Ownership
Public
Employees
20
Market Cap
-
Website
http://www.cellectar.com
Introduction

Cellectar Biosciences, Inc. engages in the development of phospholipid drug conjugates (PDCs) for the treatment and imaging of cancer. Its portfolio includes CLR 131, which seeks to treat relapse or refractory multiple myeloma, CLR 125, which intends to treat micro metastatic disease, CLR 124 which could detect tumors and metastases in a broad range of cancers and CLR 1502, a cancer-targeting near-infrared-fluorophore optical imaging PDC for intraoperative tumor and tumor margin illumination. The company was founded in June 1996 and is headquartered in Florham Park, NJ.

Clinical Trials

16

Active:8
Completed:6

Trial Phases

3 Phases

Phase 1:10
Phase 2:5
Phase 3:1

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (16 trials with phase data)• Click on a phase to view related trials

Phase 1
10 (62.5%)
Phase 2
5 (31.3%)
Phase 3
1 (6.3%)

Novel Targeted Radiotherapy in Pediatric Patients With Inoperable Relapsed or Refractory HGG

Phase 1
Active, not recruiting
Conditions
High-Grade Glioma
Interventions
First Posted Date
2022-11-09
Last Posted Date
2025-03-28
Lead Sponsor
Cellectar Biosciences, Inc.
Target Recruit Count
50
Registration Number
NCT05610891
Locations
🇺🇸

Stanford University, Palo Alto, California, United States

🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

🇺🇸

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States

and more 5 locations

Dose Escalation Study of CLR 131 in Children, Adolescents, and Young Adults With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma

Phase 1
Active, not recruiting
Conditions
DIPG
Neuroblastoma
Ewing Sarcoma
Pediatric Solid Tumor
Pediatric Brain Tumor
Rhabdomyosarcoma
Osteosarcoma
Pediatric Lymphoma
Interventions
First Posted Date
2018-03-27
Last Posted Date
2025-03-28
Lead Sponsor
Cellectar Biosciences, Inc.
Target Recruit Count
30
Registration Number
NCT03478462
Locations
🇺🇸

Lucile Packard Children's Hospital, Palo Alto, California, United States

🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

🇺🇸

Duke University, Chapel Hill, North Carolina, United States

and more 5 locations

Study of Iopofosine I 131 (CLR 131) in Select B-Cell Malignancies (CLOVER-1) and Pivotal Expansion in Waldenstrom Macroglobulinemia

Phase 2
Active, not recruiting
Conditions
Small Lymphocytic Lymphoma
Lymphoplasmacytic Lymphoma
Waldenstrom Macroglobulinemia
Multiple Myeloma
Marginal Zone Lymphoma
Diffuse Large B Cell Lymphoma
Chronic Lymphocytic Leukemia
Mantle Cell Lymphoma
Central Nervous System Lymphoma
Interventions
Drug: Iopofosine I 131 single dose
Drug: Iopofosine I 131 multiple dose
Drug: Iopofosine I 131 fractionated dose
First Posted Date
2016-11-02
Last Posted Date
2025-03-26
Lead Sponsor
Cellectar Biosciences, Inc.
Target Recruit Count
120
Registration Number
NCT02952508
Locations
🇬🇧

Cellectar Biosciences site, London, United Kingdom

🇹🇷

Cellectar Biosciences, Istanbul, Turkey

🇮🇱

Cellectar Biosciences Site, Jerusalem, Israel

Dose Escalation Study of I-131-CLR1404 in Patients With Relapsed or Refractory Multiple Myeloma

Phase 1
Completed
Conditions
Multiple Myeloma
Interventions
First Posted Date
2014-10-30
Last Posted Date
2023-02-22
Lead Sponsor
Cellectar Biosciences, Inc.
Target Recruit Count
31
Registration Number
NCT02278315
Locations
🇺🇸

Mayo Clinic, Jacksonville, Florida, United States

🇺🇸

Loyola University Medical Center, Maywood, Illinois, United States

🇺🇸

Karmanos Cancer Institute, Detroit, Michigan, United States

and more 1 locations

Imaging Trial With I-124-CLR1404 in Patients With Newly Diagnosed or Recurrent Glioblastoma

Phase 2
Terminated
Conditions
Glioblastoma
Interventions
First Posted Date
2013-07-12
Last Posted Date
2015-09-09
Lead Sponsor
Cellectar Biosciences, Inc.
Target Recruit Count
7
Registration Number
NCT01898273
Locations
🇺🇸

City of Hope, Duarte, California, United States

🇺🇸

Moffitt Cancer Center and Research Institute, Tampa, Florida, United States

🇺🇸

University of Maryland School of Medicine, Baltimore, Maryland, United States

and more 6 locations
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News

Cellectar Biosciences Submits Phase 1b Protocol for CLR 125 Radiopharmaceutical in Triple-Negative Breast Cancer

Cellectar Biosciences has submitted a Phase 1b dose-finding study protocol to the FDA for CLR 125, an iodine-125 Auger-emitting radiopharmaceutical targeting relapsed triple-negative breast cancer.

Cellectar's Iopofosine I 131 Doubles Survival in Pediatric Brain Cancer Trial

Cellectar Biosciences reported that iopofosine I 131 achieved 5.4 months average progression-free survival in pediatric high-grade glioma patients, doubling the reported median of 2.25 months.

Cellectar Biosciences Raises $2.5 Million Through Warrant Exercise to Advance Cancer Drug Development

Cellectar Biosciences secured $2.5 million in funding through the exercise of existing warrants at a reduced price of $0.3041 per share, with proceeds designated for general corporate purposes and operating expenses.

Cellectar Biosciences Advances Iopofosine I 131 and Radioconjugate Pipeline at Biotech Showcase

Cellectar Biosciences plans to highlight its 2025 strategic initiatives at the Biotech Showcase during the JP Morgan Healthcare Conference.

Cellectar Biosciences to Pursue Strategic Options for Iopofosine I 131, Prioritizes Solid Tumor Radiotherapies

Cellectar Biosciences is exploring strategic alternatives for iopofosine I 131 after recent FDA feedback on regulatory pathways.

Cellectar Biosciences' Iopofosine I 131 Shows Promise in Waldenstrom's Macroglobulinemia

Cellectar Biosciences reported positive Phase 2 CLOVER-WaM study results for Iopofosine I 131 in relapsed/refractory Waldenstrom's Macroglobulinemia (WM).

Cellectar Biosciences Advances Iopofosine I 131 in Multiple Myeloma and Waldenstrom’s Macroglobulinemia Trials

Cellectar Biosciences is progressing its lead therapeutic, iopofosine I 131, through clinical trials targeting relapsed/refractory Waldenstrom’s macroglobulinemia (WM) and multiple myeloma (MM).

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