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YZYBIO-B

YZYBIO-B logo
🇨🇳China
Ownership
Public, Subsidiary
Established
2010-07-08
Employees
114
Market Cap
-
Website
http://yzybio.com
Introduction

Wuhan Youzhiyou Biopharmaceutical Co., Ltd. is a biotechnology company dedicated to developing bispecific antibody (BsAb) -based therapies for the treatment of cancer-related complications, cancer, and senile ophthalmology to address medical needs in the fields of oncology and geriatric ophthalmology. The company's mission is to develop innovative medicines and protect human health.

Since its establishment in 2010, Tomochiyo Biotech has continued to innovate independently, lay out and deepen the field of bispecific antibodies, and has developed 4 innovative platforms, including the self-developed YBODY platform, the Check-body platform, the Nano-YbodyTM platform, and the UVAX platform developed in cooperation with the Wuhan Institute of Virology. The company has designed and developed seven clinical-stage drug candidate pipelines.

Clinical Trials

8

Active:2
Completed:5

Trial Phases

3 Phases

Phase 1:6
Phase 2:1
Phase 3:1

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (8 trials with phase data)• Click on a phase to view related trials

Phase 1
6 (75.0%)
Phase 2
1 (12.5%)
Phase 3
1 (12.5%)

Treatment of Malignant Ascites Caused by Advanced Epithelial Solid Tumors With M701 Bispecific Antibody

Phase 3
Active, not recruiting
Conditions
Malignant Ascites
Interventions
Procedure: paracentesis
First Posted Date
2024-05-29
Last Posted Date
2025-07-20
Lead Sponsor
Wuhan YZY Biopharma Co., Ltd.
Target Recruit Count
312
Registration Number
NCT06432296
Locations
🇨🇳

The First Medical Center of Chinese PLA General Hospital, Beijing, Beijing, China

🇨🇳

Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China

Treat Malignant Ascites Caused by Gastrointestinal or Ovarian Cancer With M701 Bispecific Antibody

Phase 2
Completed
Conditions
Malignant Ascites
Interventions
Drug: paracentesis
First Posted Date
2024-02-20
Last Posted Date
2025-07-20
Lead Sponsor
Wuhan YZY Biopharma Co., Ltd.
Target Recruit Count
115
Registration Number
NCT06266091
Locations
🇨🇳

The First Medical Center of Chinese PLA General Hospital, Beijing, Beijing, China

A Trial of Y101D in Combination With Gemcitabine and Albumin Paclitaxel in Patients With Advanced Pancreatic Cancer

Phase 1
Active, not recruiting
Conditions
Advanced Pancreatic Adenocarcinoma
Interventions
First Posted Date
2024-02-20
Last Posted Date
2025-07-20
Lead Sponsor
Wuhan YZY Biopharma Co., Ltd.
Target Recruit Count
71
Registration Number
NCT06266143
Locations
🇨🇳

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China

A Phase Ib/II Clinical Trial of M701 in the Treatment of Malignant Pleural Effusions Caused by NSCLC

Phase 1
Recruiting
Conditions
Malignant Pleural Effusions
NSCLC Stage IV
Interventions
Drug: M701 pleural infusion
Procedure: Pleural drainage
First Posted Date
2022-09-16
Last Posted Date
2025-07-20
Lead Sponsor
Wuhan YZY Biopharma Co., Ltd.
Target Recruit Count
96
Registration Number
NCT05543330
Locations
🇨🇳

Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, Zhejiang, China

A Trial of Y101D, a PD-L1/TGF-β Bispecific Antibody, in Patients With Metastatic or Locally Advanced Solid Tumors

Phase 1
Completed
Conditions
Metastatic or Locally Advanced Solid Tumors
Interventions
Drug: Cohort 1 of Y101D
Drug: Cohort 2 of Y101D
Drug: Cohort 3 of Y101D
Drug: Cohort 4 of Y101D
Drug: Cohort 5 of Y101D
First Posted Date
2021-08-31
Last Posted Date
2025-07-20
Lead Sponsor
Wuhan YZY Biopharma Co., Ltd.
Target Recruit Count
50
Registration Number
NCT05028556
Locations
🇨🇳

Cancer Prevention Center, Sun Yat-sen University, Guangzhou, Guangdong, China

🇨🇳

Henan Cancer Hospital, Zhengzhou, Henan, China

🇨🇳

Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China

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