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Synlogic

Synlogic logo
🇺🇸United States
Ownership
Public
Established
2014-01-01
Employees
6
Market Cap
$17.4M
Website
http://www.synlogictx.com
Introduction

Synlogic, Inc. is a biopharmaceutical company which engages in the discovery and development of synthetic biotic medicines. It focuses on phenylketonuria, enteric hyperoxaluria, immuno-oncology solid tumors, inflammatory bowel disease, and vaccines and other inflammatory programs. The company was founded by James J. Collins and Timothy K. Lu on December 20, 2007 and is headquartered in Cambridge, MA.

Clinical Trials

12

Active:2
Completed:7

Trial Phases

4 Phases

Early Phase 1:1
Phase 1:9
Phase 2:1
+1 more phases

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (12 trials with phase data)• Click on a phase to view related trials

Phase 1
9 (75.0%)
Early Phase 1
1 (8.3%)
Phase 2
1 (8.3%)
Phase 3
1 (8.3%)

Efficacy and Safety of SYNB1934 in Patients With PKU (SYNPHENY-3)

Phase 3
Terminated
Conditions
Phenylketonuria
Interventions
Drug: SYNB1934v1
Drug: Placebo
First Posted Date
2023-03-10
Last Posted Date
2024-06-20
Lead Sponsor
Synlogic
Target Recruit Count
35
Registration Number
NCT05764239
Locations
🇺🇸

Science 37, Culver City, California, United States

🇺🇸

Children's Hospital Orange County, Orange, California, United States

🇺🇸

Stanford University, Department of Pediatrics, Palo Alto, California, United States

and more 18 locations

Safety, Tolerability and Pharmacodynamics of SYNB1353 in Healthy Adult Volunteers

Phase 1
Completed
Conditions
Homocystinuria
Interventions
First Posted Date
2022-07-18
Last Posted Date
2023-03-17
Lead Sponsor
Synlogic
Target Recruit Count
31
Registration Number
NCT05462132
Locations
🇺🇸

High Point Clinical Trials Center, High Point, North Carolina, United States

Safety, Tolerability, and Pharmacodynamics of SYNB8802v1 in Subjects With History of Gastric Bypass Surgery or Short-bowel Syndrome

Early Phase 1
Completed
Conditions
Enteric Hyperoxaluria
Interventions
Other: Placebo
First Posted Date
2022-05-17
Last Posted Date
2023-03-17
Lead Sponsor
Synlogic
Target Recruit Count
11
Registration Number
NCT05377112
Locations
🇺🇸

PPD, part of Thermo Fisher Scientific, Austin, Texas, United States

Safety and Tolerability of SYNB1934 in Healthy Adult Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2021-07-30
Last Posted Date
2022-05-18
Lead Sponsor
Synlogic
Target Recruit Count
106
Registration Number
NCT04984525
Locations
🇺🇸

High Point Clinical Trials Center, High Point, North Carolina, United States

Safety and Tolerability of SYNB8802 in Healthy Adult Volunteers and Adult Subjects With Enteric Hyperoxaluria

Phase 1
Completed
Conditions
Healthy
Enteric Hyperoxaluria
Interventions
Drug: Placebo
First Posted Date
2020-11-16
Last Posted Date
2024-03-08
Lead Sponsor
Synlogic
Target Recruit Count
77
Registration Number
NCT04629170
Locations
🇺🇸

Urological Associates of Southern Arizona (open to remote participation), Tucson, Arizona, United States

🇺🇸

Genesis Clinical Research, Tampa, Florida, United States

🇺🇸

Knoxville Kidney Center, Knoxville, Tennessee, United States

and more 1 locations
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News

Synlogic's Novel Probiotic Therapy Shows Promise in Phase 2 PKU Trial, Advancing to Phase 3

Synlogic's engineered probiotic SYNB1934 demonstrated a significant 34% reduction in phenylalanine levels in phenylketonuria patients during Phase 2 trials, outperforming its predecessor SYNB1618.

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