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Nurix Therapeutics

Nurix Therapeutics logo
🇺🇸United States
Ownership
Public
Established
2012-01-01
Employees
284
Market Cap
$1.5B
Website
http://www.nurixtx.com
Introduction

Nurix Therapeutics, Inc. is a clinical stage biopharmaceutical company. It engages in the business of discovering, developing, and commercializing innovative small molecules and antibody therapies based on the modulation of cellular protein levels as a novel treatment approach for cancer, inflammatory conditions, and other challenging diseases. The company was founded by John Kuriyan, Michael Rapé, and Arthur Weiss in 2009 and is headquartered in San Francisco, CA.

Clinical Trials

7

Active:0
Completed:2

Trial Phases

1 Phases

Phase 1:7

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (7 trials with phase data)• Click on a phase to view related trials

Phase 1
7 (100.0%)

Relative Bioavailability of NX-5948 Tablets Vs Capsules and the Effect of Covariates on the PK of NX-5948 Tablets

Phase 1
Recruiting
Conditions
Healthy Volunteer
Interventions
Drug: NX-5948 capsule
Drug: NX-5948 tablet
First Posted Date
2024-12-04
Last Posted Date
2024-12-19
Lead Sponsor
Nurix Therapeutics, Inc.
Target Recruit Count
18
Registration Number
NCT06717269
Locations
🇺🇸

Celerion, Lincoln, Nebraska, United States

Absolute Bioavailability, Absorption, Metabolism, Excretion, and Mass Balance Study of [14C] NX-5948

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2024-11-15
Last Posted Date
2025-03-12
Lead Sponsor
Nurix Therapeutics, Inc.
Target Recruit Count
8
Registration Number
NCT06691828
Locations
🇺🇸

Celerion, Lincoln, Nebraska, United States

A Food-Effect, Drug-Drug Interaction, and Pharmacokinetics Study of NX-5948 in Healthy Adult Subjects

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Drug: IP
Drug: Matching Placebo
First Posted Date
2024-09-19
Last Posted Date
2025-03-25
Lead Sponsor
Nurix Therapeutics, Inc.
Target Recruit Count
32
Registration Number
NCT06593457
Locations
🇺🇸

Celerion, Lincoln, Nebraska, United States

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

Phase 1
Recruiting
Conditions
Chronic Lymphocytic Leukemia (CLL)
Small Lymphocytic Lymphoma (SLL)
Diffuse Large B Cell Lymphoma (DLBCL)
Follicular Lymphoma (FL)
Mantle Cell Lymphoma (MCL)
Marginal Zone Lymphoma (MZL)
Waldenstrom Macroglobulinemia (WM)
Primary Central Nervous System Lymphoma (PCNSL)
Secondary Central Nervous System Lymphoma (SCNSL)
Interventions
First Posted Date
2021-11-23
Last Posted Date
2025-06-15
Lead Sponsor
Nurix Therapeutics, Inc.
Target Recruit Count
572
Registration Number
NCT05131022
Locations
🇫🇷

CHU Bordeaux, Pessac, France

🇮🇹

IRCCS - AOU di Bologna, Bologna, Italy

🇮🇹

ASST Spedali Civili Brescia, Brescia, Italy

and more 58 locations

A Study of DeTIL-0255 in Adults With Advanced Malignancies

Phase 1
Terminated
Conditions
Endometrial Cancer
Cervical Cancer
Platinum-resistant Ovarian Cancer
First Posted Date
2021-11-04
Last Posted Date
2024-05-03
Lead Sponsor
Nurix Therapeutics, Inc.
Target Recruit Count
5
Registration Number
NCT05107739
Locations
🇺🇸

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, United States

🇺🇸

Roswell Park Comprehensive Cancer Center, Buffalo, New York, United States

🇺🇸

Allegheny General Hospital, Pittsburgh, Pennsylvania, United States

and more 1 locations
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