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TScan Therapeutics

TScan Therapeutics logo
🇺🇸United States
Ownership
Public
Established
2018-01-01
Employees
154
Market Cap
$292.9M
Website
http://www.tscan.com
Introduction

TScan Therapeutics, Inc. discovers and develops transformative T cell therapies (TCR-T) to treat liquid cancers, solid tumors and other serious diseases. Its platform identifies previously uncharacterized, clinically-derived shared T cell antigens and all off-target TCR interactions, to enable the development of efficacious TCR-Ts. The company was founded by Christoph H. Westphal, Stephen Elledge, Lea Hachigian, and Tomasz Kula in 2018 and is headquartered in Boston, MA.

Clinical Trials

8

Active:0
Completed:1

Trial Phases

1 Phases

Phase 1:2

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (2 trials with phase data)• Click on a phase to view related trials

Phase 1
2 (100.0%)

A Long Term Follow-up Study of TScan TCR-T Products

Not yet recruiting
Conditions
AML
ALL
MDS
First Posted Date
2025-05-16
Last Posted Date
2025-05-16
Lead Sponsor
TScan Therapeutics, Inc.
Target Recruit Count
1000
Registration Number
NCT06976736
Locations
🇺🇸

City of Hope, Duarte, California, United States

🇺🇸

Mount Sinai, New York, New York, United States

A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients with Autoimmune Disease

Recruiting
Conditions
Autoimmune Diseases
Ulcerative Colitis
Multiple Sclerosis
Scleroderma
Ankylosing Spondylitis
Celiac Disease
Non-radiographic Axial Spondyloarthritis (nr-axSpA)
Crohn's Disease
Birdshot Chorioretinitis
First Posted Date
2024-09-09
Last Posted Date
2024-09-09
Lead Sponsor
TScan Therapeutics, Inc.
Target Recruit Count
300
Registration Number
NCT06587828
Locations
🇺🇸

Arizona Arthritis & Rheumatology, PLLC, Phoenix, Arizona, United States

🇺🇸

Inland Empire Gastroenterology, Murrieta, California, United States

🇺🇸

Knowledge Research Center, Orange, California, United States

and more 15 locations

A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors

Phase 1
Recruiting
Conditions
HPV - Anogenital Human Papilloma Virus Infection
HPV-Related Squamous Cell Carcinoma
HPV-Related Endocervical Adenocarcinoma
HPV-Related Anal Squamous Cell Carcinoma
HPV-Related Penile Squamous Cell Carcinoma
HPV-Related Vulvar Squamous Cell Carcinoma
HPV Positive Rectal Squamous Cell Carcinoma
HPV-Related Cervical Carcinoma
HPV-Associated Vaginal Adenocarcinoma
Melanoma
Interventions
Biological: TSC-204-A0201 + TSC-204-C0702
Biological: TSC-204-A0201 + TSC-200-A0201
Biological: TSC-204-C0702 + TSC-200-A0201
Biological: TSC-204-A0201 + TSC-203-A0201
Biological: TSC-204-C0702 + TSC-203-A0201
Biological: TSC-204-A0201 + TSC-204-A0101
Biological: TSC-204-A0201 + TSC-201-B0702
Biological: TSC-204-C0702 + TSC-204-A0101
Biological: TSC-204-C0702 + TSC-201-B0702
Biological: TSC-200-A0201 + TSC-203-A0201
Biological: TSC-200-A0201 + TSC-204-A0101
Biological: TSC-200-A0201 + TSC-201-B0702
Biological: TSC-203-A0201 + TSC-204-A0101
Biological: TSC-203-A0201 + TSC-201-B0702
Biological: TSC-204-A0201 + TSC-202-A0201
Biological: TSC-204-C0702 + TSC-202-A0201
Biological: TSC-200-A0201 + TSC-202-A0201
Biological: TSC-203-A0201 + TSC-202-A0201
Biological: TSC-204-A0101 + TSC-202-A0201
Biological: TSC-201-B0702 + TSC-202-A0201
First Posted Date
2023-08-03
Last Posted Date
2025-04-02
Lead Sponsor
TScan Therapeutics, Inc.
Target Recruit Count
840
Registration Number
NCT05973487
Locations
🇺🇸

HonorHealth Research and Innovation Institute, Scottsdale, Arizona, United States

🇺🇸

University of California San Diego, San Diego, California, United States

🇺🇸

Yale Cancer Center, New Haven, Connecticut, United States

and more 17 locations

A Screening Study to Collect Samples for TAA, HLA & HLA Loss of Heterozygosity in Patients With Metastatic Solid Tumors

Recruiting
Conditions
Head and Neck Cancer
Cervical Cancer
Non Small Cell Lung Cancer
HPV16 Related Cancers
Sarcoma
Uveal Melanoma
NUT Carcinoma
First Posted Date
2023-04-13
Last Posted Date
2025-06-26
Lead Sponsor
TScan Therapeutics, Inc.
Target Recruit Count
1150
Registration Number
NCT05812027
Locations
🇺🇸

University of Chicago, Chicago, Illinois, United States

🇺🇸

Oncology Hematology Care, Cincinnati, Ohio, United States

🇺🇸

Baylor College of Medicine, Houston, Texas, United States

and more 18 locations

A Study of TSC-100 and TSC-101 in AML, ALL and MDS in Patients Undergoing Allogeneic Peripheral Blood Stem Transplantation

Phase 1
Recruiting
Conditions
AML
Myelodysplastic Syndromes
ALL, Adult
Interventions
Other: Control
Drug: SOC + TSC-100
Drug: SOC + TSC-101
First Posted Date
2022-07-26
Last Posted Date
2025-05-18
Lead Sponsor
TScan Therapeutics, Inc.
Target Recruit Count
75
Registration Number
NCT05473910
Locations
🇺🇸

Memorial Healthcare System, Hollywood, Florida, United States

🇺🇸

Baylor University Medical Center, Dallas, Texas, United States

🇺🇸

City of Hope, Duarte, California, United States

and more 12 locations
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