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Enliven Therapeutics

🇺🇸United States
Ownership
Public
Employees
46
Market Cap
$1B
Website
http://www.enliventherapeutics.com
Introduction

Enliven Therapeutics, Inc. operates as a clinical stage precision oncology company. It is focused on the discovery and development of next-generation small molecule kinase inhibitors and advancing Enliven's pipeline of precision oncology product candidates. The company was founded by Sam S. Kintz, Joe P. Lyssikatos, and Anish Patel in June 2019 and is headquartered in Boulder, CO.

ELVN-001 for the Treatment of Chronic Myeloid Leukemia With and Without T315I Mutation in Japanese Participants

Phase 1
Recruiting
Conditions
CML (Chronic Myelogenous Leukemia)
Chronic Phase CML
Interventions
First Posted Date
2025-01-22
Last Posted Date
2025-01-29
Lead Sponsor
Enliven Therapeutics
Target Recruit Count
21
Registration Number
NCT06787144
Locations
🇯🇵

Akita University Hospital, Akita-shi, Akita-ken, Japan

🇯🇵

Aiiku Hospital, Sapporo, Hokkaido, Japan

🇯🇵

Osaka University Hospital, Suita-shi, Osaka, Japan

and more 1 locations

ELVN-002 with Trastuzumab +/- Chemotherapy in HER2+ Solid Tumors, Colorectal and Breast Cancer

Phase 1
Recruiting
Conditions
HER2-positive Gastric Cancer
Colorectal Cancer
HER2 Amplification
HER2-positive Breast Cancer
HER2 Positive Solid Tumors
Interventions
First Posted Date
2024-03-25
Last Posted Date
2025-01-09
Lead Sponsor
Enliven Therapeutics
Target Recruit Count
275
Registration Number
NCT06328738
Locations
🇮🇹

Azienda Ospedaliero-Universitaria Renato Dulbecco, Catanzaro, Italy

🇺🇸

BRCR Medical Center Inc., Plantation, Florida, United States

🇺🇸

Washington University, Saint Louis, Missouri, United States

and more 28 locations

ELVN-002 in HER2 Mutant Non-Small Cell Lung Cancer

Phase 1
Recruiting
Conditions
HER2 Mutant Non-small Cell Lung Cancer
HER2-positive Metastatic Breast Cancer
HER2 Gene Mutation
HER2 Amplification
Interventions
First Posted Date
2022-12-14
Last Posted Date
2025-01-09
Lead Sponsor
Enliven Therapeutics
Target Recruit Count
198
Registration Number
NCT05650879
Locations
🇺🇸

University of Colorado - Anschutz Medical Campus - PPDS, Aurora, Colorado, United States

🇺🇸

Advent Health Orlando, Orlando, Florida, United States

🇺🇸

BRCR Medical Center Inc, Plantation, Florida, United States

and more 36 locations

A Phase 1a/1b Study of ELVN-001 for the Treatment Chronic Myeloid Leukemia

Phase 1
Recruiting
Conditions
Chronic Myeloid Leukemia
Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive
Cml
Interventions
First Posted Date
2022-03-31
Last Posted Date
2025-02-27
Lead Sponsor
Enliven Therapeutics
Target Recruit Count
180
Registration Number
NCT05304377
Locations
🇮🇱

The Galilee Medical Center, Nahariya, Israel

🇮🇱

Rabin Medical Center, Petah Tikva, Israel

🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

and more 31 locations
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