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YALE UNIVERSITY

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1701-10-09

Employees: 10K

Market Cap: -

Website: http://www.yale.edu

Clinical Trials

Testing the Interactive Effects of Delta-9-Tetrahydrocannabinol and Pregnenolone

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: Active Pregnenolone
Drug: Active Delta-9-THC
Drug: Placebo

First Posted Date: 2015-10-15

Last Posted Date: 2023-08-07

Lead Sponsor: Yale University

Target Recruit Count: 38

Registration Number: NCT02576912

Locations: 🇺🇸
Biological Studies Unit at the VA Connecticut Healthcare System, Yale School of Medicine, West Haven, Connecticut, United States

Study of High-dose Influenza Vaccine Efficacy by Repeated Dosing IN Gammopathy Patients

Phase 2

Completed

Conditions: Plasma Cell Disorders
Influenza
Waldenstrom's Macroglobulinemia
MGUS
Multiple Myeloma

Interventions: Biological: Fluzone High Dose Vaccine
Biological: Standard of care/Placebo

First Posted Date: 2015-10-02

Last Posted Date: 2019-01-30

Lead Sponsor: Yale University

Target Recruit Count: 122

Registration Number: NCT02566265

Locations: 🇺🇸
Yale University, New Haven, Connecticut, United States

A Smoking Cessation Intervention for Yale Dining Employees

Phase 4

Completed

Conditions: Smoking Cessation

Interventions: Behavioral: Contingency management
Drug: Nicotine replacement therapy
Drug: Varenicline
Behavioral: Additional behavioral support

First Posted Date: 2015-09-29

Last Posted Date: 2018-04-09

Lead Sponsor: Yale University

Target Recruit Count: 25

Registration Number: NCT02562521

Locations: 🇺🇸
Yale University, New Haven, Connecticut, United States

Nicotinic Cholinergic Modulation as a Novel Treatment Strategy for Aggression Associated With Autism

Phase 1

Completed

Conditions: Autism Spectrum Disorder
Aggression
Irritability

Interventions: Drug: Transdermal nicotine
Other: Transdermal placebo

First Posted Date: 2015-09-16

Last Posted Date: 2022-05-06

Lead Sponsor: Yale University

Target Recruit Count: 8

Registration Number: NCT02552147

Locations: 🇺🇸
Yale University, New Haven, Connecticut, United States

Exercise in Genetic Cardiovascular Conditions

Completed

Conditions: Hypertrophic Cardiomyopathy
Long QT Syndrome

First Posted Date: 2015-09-15

Last Posted Date: 2023-09-05

Lead Sponsor: Yale University

Target Recruit Count: 4299

Registration Number: NCT02549664

Locations: 🇺🇸
Lurie Children's, Chicago, Illinois, United States
🇺🇸
University of California Irvine, Orange, California, United States
🇺🇸
University of Iowa, Iowa City, Iowa, United States

and more 33 locations

Diagnosing and Targeting Mechanisms of Diuretic Resistance in Heart Failure

Phase 1

Completed

Conditions: Heart Failure

Interventions: Drug: Increased Intravenous Bolus Loop Diuretic Dose (Bumetanide or Furosemide)
Drug: IV Chlorothiazide

First Posted Date: 2015-09-11

Last Posted Date: 2023-11-22

Lead Sponsor: Yale University

Target Recruit Count: 458

Registration Number: NCT02546583

Locations: 🇺🇸
Yale University, New Haven, Connecticut, United States

Oxytocin and Affect Processing in Posttraumatic Stress Disorder

Phase 2

Completed

Conditions: Posttraumatic Stress Disorder (PTSD)

Interventions: Drug: Oxytocin
Drug: Placebo

First Posted Date: 2015-09-11

Last Posted Date: 2020-04-08

Lead Sponsor: Yale University

Target Recruit Count: 11

Registration Number: NCT02546570

Locations: 🇺🇸
Yale University, New Haven, Connecticut, United States

Modification and Evaluation of the Educational Mobile Games Heroes of Knowledge in Children

Not Applicable

Completed

Conditions: Math Knowledge

Interventions: Behavioral: Heroes of Knowledge
Behavioral: Attention/Time Control Game

First Posted Date: 2015-09-10

Last Posted Date: 2016-12-20

Lead Sponsor: Yale University

Target Recruit Count: 133

Registration Number: NCT02546245

Locations: 🇺🇸
Yale University, New Haven, Connecticut, United States

Development of Patient Centered Virtual Multimedia Interactive Informed Consent Tool to Improve Patient Comprehension and Consent

Completed

Conditions: Patient Centered Outcomes Research

Interventions: Device: Patient Centered Virtual Multimedia Interactive Informed Consent tool (VIC)

First Posted Date: 2015-09-02

Last Posted Date: 2019-05-03

Lead Sponsor: Yale University

Target Recruit Count: 50

Registration Number: NCT02537886

Locations: 🇺🇸
Yale School of Medicine: Dept of Emergency Medicine, New Haven, Connecticut, United States

A Comparison of Incisional Negative-Pressure Wound Therapy Versus Conventional Dressings Following Abdominal Surgery

Not Applicable

Withdrawn

Conditions: Abdominal Reconstruction

Interventions: Procedure: Vacuum-assisted closure (VAC) therapy
Procedure: Gauze dressing

First Posted Date: 2015-08-27

Last Posted Date: 2018-01-16

Lead Sponsor: Yale University

Registration Number: NCT02534116

Locations: 🇺🇸
Yale University, Section of Plastic Surgery, New Haven, Connecticut, United States

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