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Hepion Pharmaceuticals

Hepion Pharmaceuticals logo
🇺🇸United States
Ownership
Public
Employees
22
Market Cap
$4.5M
Website
http://www.hepionpharma.com
Introduction

Hepion Pharmaceuticals, Inc. is a biopharmaceutical company, which engages in the development of drug therapy for treatment of chronic liver diseases. It focuses on the development of its product candidate rencofilstat, a cyclophilin inhibitor that targets biochemical pathways involved in the progression of liver disease. The company was founded on May 15, 2013 and is headquartered in Edison, NJ.

Clinical Trials

8

Active:4
Completed:4

Trial Phases

3 Phases

Early Phase 1:1
Phase 1:4
Phase 2:3

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (8 trials with phase data)• Click on a phase to view related trials

Phase 1
4 (50.0%)
Phase 2
3 (37.5%)
Early Phase 1
1 (12.5%)

Single Dose ADME Study of [14C]-Rencofilstat in Healthy Male Subjects

Early Phase 1
Completed
Conditions
NASH With Fibrosis
Interventions
Drug: [14C]-rencofilstat 225mg
First Posted Date
2023-02-21
Last Posted Date
2024-10-03
Lead Sponsor
Hepion Pharmaceuticals, Inc.
Target Recruit Count
6
Registration Number
NCT05737433
Locations
🇬🇧

Quotient Sciences, Nottingham, United Kingdom

A Study to Evaluate the Safety and Efficacy of Rencofilstat in Adult Subjects With NASH F3

Phase 2
Completed
Conditions
NASH With Fibrosis
Interventions
Drug: rencofilstat, 75 mg
Drug: rencofilstat, 150mg
Drug: rencofilstat, 225 mg
First Posted Date
2022-07-15
Last Posted Date
2024-06-13
Lead Sponsor
Hepion Pharmaceuticals, Inc.
Target Recruit Count
60
Registration Number
NCT05461105
Locations
🇺🇸

Arizona Liver Health-Chandler, Chandler, Arizona, United States

🇺🇸

Arizona Liver Health-Glendale, Peoria, Arizona, United States

🇺🇸

Adobe Clinical Research, LLC, Tucson, Arizona, United States

and more 17 locations

A Study to Evaluate the Efficacy and Safety of Rencofilstat in Subjects With NASH and Advanced Liver Fibrosis

Phase 2
Active, not recruiting
Conditions
Nonalcoholic Steatohepatitis (NASH)
NAFLD
Fibrosis, Liver
Interventions
Drug: Placebo
First Posted Date
2022-06-02
Last Posted Date
2024-05-03
Lead Sponsor
Hepion Pharmaceuticals, Inc.
Target Recruit Count
120
Registration Number
NCT05402371
Locations
🇺🇸

Medical Affiliated Research Center, Huntsville, Alabama, United States

🇺🇸

Arizona Liver Health-Chandler, Chandler, Arizona, United States

🇺🇸

Arizona Liver Health, Peoria, Arizona, United States

and more 34 locations

A Study of CRV431 Dosed Once Daily in NASH Induced F2 and F3 Subjects

Phase 2
Completed
Conditions
Fibrosis, Liver
NAFLD - Nonalcoholic Fatty Liver Disease
NASH - Nonalcoholic Steatohepatitis
Interventions
Drug: Placebo (3 softgels)
Drug: CRV431 75mg
Drug: Placebo (1 softgel)
Drug: CRV431 225mg
First Posted Date
2020-07-21
Last Posted Date
2022-07-15
Lead Sponsor
Hepion Pharmaceuticals, Inc.
Target Recruit Count
47
Registration Number
NCT04480710
Locations
🇺🇸

Conquest Clinical Research, Orange, California, United States

🇺🇸

Alliance Clinical Research, Poway, California, United States

🇺🇸

La Salud Research, Inc., Miami, Florida, United States

and more 7 locations

A Study in Healthy Volunteers

Phase 1
Completed
Conditions
Liver Diseases
Hepatitis B
Infectious Disease
Interventions
First Posted Date
2018-07-24
Last Posted Date
2021-12-01
Lead Sponsor
Hepion Pharmaceuticals, Inc.
Target Recruit Count
92
Registration Number
NCT03596697
Locations
🇺🇸

Celerion, Inc, Lincoln, Nebraska, United States

🇺🇸

Pinnacle Clinical Research, San Antonio, Texas, United States

News

No news found

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