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Tiziana Life Sciences

🇬🇧United Kingdom
Ownership
-
Employees
9
Market Cap
$125.8M
Website
Introduction

Tiziana Life Sciences Ltd. is a clinical-stage biotechnology company, which engages in the research and development of biotechnological and pharmaceutical products. It specializes in developing transformative therapies for neurodegenerative and lung diseases. The company was founded by Gabriele Marco Antonio Cerrone on February 11, 1998 and is headquartered in London, the United Kingdom.

Nasal Foralumab in Patients With Non-Active Secondary Progressive Multiple Sclerosis

Phase 2
Recruiting
Conditions
Non-Active Secondary Progressive Multiple Sclerosis
Interventions
First Posted Date
2025-03-24
Last Posted Date
2025-06-06
Lead Sponsor
Tiziana Life Sciences LTD
Target Recruit Count
55
Registration Number
NCT06890923
Locations
🇺🇸

Brigham and Women's Hospital, Boston, Massachusetts, United States

Safety, Tolerability and Immune Effects of the Nasal Foralumab in Healthy Human Volunteers

Phase 1
Completed
Conditions
Safety
Tolerability
Interventions
Drug: Foralumab Nasal
Drug: Placebo
First Posted Date
2025-03-17
Last Posted Date
2025-03-17
Lead Sponsor
Tiziana Life Sciences LTD
Target Recruit Count
27
Registration Number
NCT06879067
Locations
🇺🇸

Ann Romney Center for Neurologic Diseases, Boston, Massachusetts, United States

Intermediate-Size Patient Population Expanded Access: Foralumab in Non-Active Secondary Progressive MS Patients

Conditions
Non-Active Secondary Progressive Multiple Sclerosis
First Posted Date
2025-01-31
Last Posted Date
2025-06-06
Lead Sponsor
Tiziana Life Sciences LTD
Registration Number
NCT06802328
Locations
🇺🇸

Brigham and Women's Hospital, Boston, Massachusetts, United States

A Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients

Phase 2
Recruiting
Conditions
Secondary Progressive Multiple Sclerosis
Interventions
Other: Placebo
First Posted Date
2024-03-05
Last Posted Date
2025-06-06
Lead Sponsor
Tiziana Life Sciences LTD
Target Recruit Count
54
Registration Number
NCT06292923
Locations
🇺🇸

Yale, North Haven, Connecticut, United States

🇺🇸

Johns Hopkins, Baltimore, Maryland, United States

🇺🇸

Brigham and Women's Hospital, Boston, Massachusetts, United States

and more 4 locations

Milciclib in Combination With Gemcitabine in Advanced NSCLC

Phase 2
Not yet recruiting
Conditions
NSCLC
First Posted Date
2022-12-15
Last Posted Date
2022-12-15
Lead Sponsor
Tiziana Life Sciences LTD
Target Recruit Count
28
Registration Number
NCT05651269

A Study of Oral Foralumab in Participants With Moderate to Severely Active Crohn's Disease

Phase 1
Withdrawn
Conditions
Crohn's Disease
Interventions
First Posted Date
2021-08-31
Last Posted Date
2022-10-20
Lead Sponsor
Tiziana Life Sciences LTD
Registration Number
NCT05028946

Phase 1b Multiple Ascending Dose Study of Foralumab in Primary and Secondary Progressive MS

Phase 1
Withdrawn
Conditions
Primary Progressive Multiple Sclerosis
Secondary Progressive Multiple Sclerosis
Multiple Sclerosis
Interventions
First Posted Date
2021-08-31
Last Posted Date
2022-03-03
Lead Sponsor
Tiziana Life Sciences LTD
Registration Number
NCT05029609

In-patient COVID-19 Study of Intranasal Foralumab

Phase 2
Withdrawn
Conditions
COVID-19 Lower Respiratory Infection
Covid19
COVID-19 Respiratory Infection
Interventions
Other: Placebo
First Posted Date
2021-07-30
Last Posted Date
2022-10-19
Lead Sponsor
Tiziana Life Sciences LTD
Registration Number
NCT04983446

Assessment of the Safety of Foralumab, an Oral Anti-CD3 Antibody, in Patients With NASH and T2DM

Phase 2
Withdrawn
Conditions
NAFLD
NASH - Nonalcoholic Steatohepatitis
T2DM (Type 2 Diabetes Mellitus)
Interventions
First Posted Date
2017-09-25
Last Posted Date
2019-09-12
Lead Sponsor
Tiziana Life Sciences LTD
Registration Number
NCT03291249

Study of Milciclib in Patients With Unresectable/Metastatic Hepatocellular Carcinoma

Phase 2
Completed
Conditions
Hepatocellular Carcinoma
Interventions
First Posted Date
2017-04-12
Last Posted Date
2021-10-12
Lead Sponsor
Tiziana Life Sciences LTD
Target Recruit Count
31
Registration Number
NCT03109886
Locations
🇬🇷

Ippokrateio General Hospital of Athens, Athens, Greece

🇬🇷

Laiko General Hospital of Athens, Athens, Greece

🇬🇷

General University Hospital of Larissa, Larissa, Greece

and more 11 locations
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