Sint Maartenskliniek

PLEASE Trial Assesses Prolonged Antibiotic Treatment for Persistent Lyme Symptoms

11 years ago

• The Persistent Lyme Empiric Antibiotic Study Europe (PLEASE) investigates optimal treatment for borreliosis-attributed persistent symptoms. • The study is a randomized, double-blind, placebo-controlled trial comparing short-term versus long-term antibiotic regimens. • Researchers aim to determine if prolonged antibiotic treatment improves patient outcomes compared to standard short-term therapy. • The trial includes patients with persistent pain, fatigue, and cognitive issues following Lyme disease, evaluating physical and mental health.