ALEXION PHARMACEUTICALS, INC.

ALEXION PHARMACEUTICALS, INC. logo
🇺🇸United States
Ownership
Public, Subsidiary
Established
1992-01-01
Employees
3.8K
Market Cap
-
Website
http://www.alexion.com

Danicopan as Add-on Therapy to a C5 Inhibitor in Paroxysmal Nocturnal Hemoglobinuria (PNH) Participants Who Have Clinically Evident Extravascular Hemolysis (EVH)(ALPHA)

First Posted Date
2020-07-14
Last Posted Date
2024-10-22
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
88
Registration Number
NCT04469465
Locations
🇬🇧

Research Site, London, United Kingdom

Study of Danicopan in Participants of Japanese Descent

Phase 1
Completed
Conditions
Interventions
First Posted Date
2020-06-30
Last Posted Date
2021-02-15
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
9
Registration Number
NCT04451434
Locations
🇦🇺

Clinical Study Site, Brisbane, Australia

Copper Concentration & Histopathologic Changes in Liver Biopsy in Participants With Wilson Disease Treated With ALXN1840

Phase 2
Completed
Conditions
Interventions
First Posted Date
2020-06-09
Last Posted Date
2024-10-18
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
31
Registration Number
NCT04422431
Locations
🇬🇧

Research Site, London, United Kingdom

Efficacy and Safety Study of IV Ravulizumab in Patients With COVID-19 Severe Pneumonia

First Posted Date
2020-04-30
Last Posted Date
2022-05-24
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
202
Registration Number
NCT04369469
Locations
🇺🇸

Rush University Medical Center, Chicago, Illinois, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

and more 35 locations

SOLIRIS® (Eculizumab) Treatment of Participants With COVID-19

First Posted Date
2020-04-21
Last Posted Date
2021-03-09
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Registration Number
NCT04355494
Locations
🇺🇸

Robert Wood Johnson University Hospital, New Brunswick, New Jersey, United States

🇺🇸

Cedars-Sinai Medical Center, Los Angeles, California, United States

🇫🇷

Hôpital Henri Mondor, Creteil, France

and more 9 locations

Ravulizumab in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria Currently Treated With High-Dose Eculizumab

First Posted Date
2020-03-25
Last Posted Date
2024-08-12
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
18
Registration Number
NCT04320602
Locations
🇬🇧

Clinical Study Site, London, United Kingdom

🇬🇧

Research Site, London, United Kingdom

A Study to Evaluate the Safety and Tolerability of CAEL-101 in Patients With AL Amyloidosis

Phase 2
Completed
Conditions
Interventions
First Posted Date
2020-03-11
Last Posted Date
2023-11-30
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
25
Registration Number
NCT04304144
Locations
🇺🇸

Clinical Trial Site, Cleveland, Ohio, United States

ALXN1830 in Patients With Warm Autoimmune Hemolytic Anemia

First Posted Date
2020-02-05
Last Posted Date
2020-07-13
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Registration Number
NCT04256148
Locations
🇺🇸

Alexion Study Site, Whittier, California, United States

An Efficacy and Safety Study of Ravulizumab in ALS Participants

First Posted Date
2020-01-30
Last Posted Date
2023-01-10
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
382
Registration Number
NCT04248465
Locations
🇨🇦

University Hospital of Quebec-Universite Laval, Québec, Quebec, Canada

🇨🇦

Royal University Hospital, Saskatoon, Saskatchewan, Canada

🇮🇪

Beaumont Hospital, Dublin, Ireland

and more 92 locations

Trial of Andexanet in Patients Receiving an Oral FXa Inhibitor Who Require Urgent Surgery

Phase 2
Terminated
Conditions
First Posted Date
2020-01-18
Last Posted Date
2023-03-22
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
10
Registration Number
NCT04233073
Locations
🇯🇵

Clinical Trial Site, Tokyo, Japan

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