ALEXION PHARMACEUTICALS, INC.

ALEXION PHARMACEUTICALS, INC. logo
🇺🇸United States
Ownership
Public, Subsidiary
Established
1992-01-01
Employees
3.8K
Market Cap
-
Website
http://www.alexion.com

Open-Label Study of Asfotase Alfa in Infants and Children ≤ 5 Years of Age With Hypophosphatasia (HPP)

Phase 2
Completed
Conditions
Interventions
First Posted Date
2010-08-05
Last Posted Date
2019-03-13
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
69
Registration Number
NCT01176266
Locations
🇫🇷

Chu de Toulouse, Toulouse, France

🇷🇺

Federal State Budgetary Institution, Moscow, Russian Federation

🇩🇪

Universitätskinderklinikum Würzburg, Würzburg, Germany

and more 20 locations

Safety and Efficacy Study of Asfotase Alfa in Adolescents and Adults With Hypophosphatasia (HPP)

Phase 2
Completed
Conditions
Interventions
First Posted Date
2010-07-15
Last Posted Date
2019-03-13
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
19
Registration Number
NCT01163149
Locations
🇨🇦

Health Sciences Centre Winnipeg, University of Manitoba, Winnipeg, Manitoba, Canada

🇺🇸

Shriner's Hospital for Children, Saint Louis, Missouri, United States

🇺🇸

Duke University Medical Center, Durham, North Carolina, United States

Safety and Efficacy of Asfotase Alfa in Juvenile Patients With Hypophosphatasia (HPP)

Phase 2
Completed
Conditions
Interventions
First Posted Date
2009-08-06
Last Posted Date
2019-04-01
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
13
Registration Number
NCT00952484
Locations
🇺🇸

Shriners Hospital for Children, Saint Louis, Missouri, United States

🇨🇦

The University of Manitoba Health Services Centre, Winnipeg, Manitoba, Canada

Safety and Efficacy Study of ENB-0040 in Juvenile Patients With Hypophosphatasia (HPP)

Phase 2
Withdrawn
Conditions
First Posted Date
2009-05-06
Last Posted Date
2023-08-04
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Registration Number
NCT00894075

Eculizumab Pharmacokinetics/Pharmacodynamics Study in Pediatric/Adolescent Paroxysmal Nocturnal Hemoglobinuria (PNH)

Phase 4
Completed
Conditions
Interventions
First Posted Date
2009-03-24
Last Posted Date
2018-10-31
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
7
Registration Number
NCT00867932

Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-Resistant aHUS

Phase 2
Completed
Conditions
Interventions
First Posted Date
2009-02-16
Last Posted Date
2015-07-23
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
16
Registration Number
NCT00844545

Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Resistant aHUS

Phase 2
Completed
Conditions
Interventions
First Posted Date
2009-02-16
Last Posted Date
2015-07-23
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
1
Registration Number
NCT00844844

Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Sensitive aHUS

Phase 2
Completed
Conditions
Interventions
First Posted Date
2009-02-16
Last Posted Date
2015-07-23
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
5
Registration Number
NCT00844428

Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-sensitive Atypical Hemolytic Uremic Syndrome (aHUS)

Phase 2
Completed
Conditions
Interventions
First Posted Date
2009-02-06
Last Posted Date
2015-07-23
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
15
Registration Number
NCT00838513

Safety and Efficacy Study of Asfotase Alfa in Severely Affected Infants With Hypophosphatasia (HPP)

Phase 1
Completed
Conditions
Interventions
First Posted Date
2008-08-29
Last Posted Date
2019-04-01
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
11
Registration Number
NCT00744042
Locations
🇺🇸

Vanderbilt Children's Hospital, Nashville, Tennessee, United States

🇺🇸

Alfred I. duPont Hospital for Children, Wilmington, Delaware, United States

🇺🇸

St. John's Hospital, Springfield, Missouri, United States

and more 7 locations
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