DeepMed Research

University of Virginia

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1819-01-01

Employees: 10K

Market Cap: -

Website: http://www.virginia.edu

Clinical Trials

Suppression of Daytime and Nighttime Luteinizing Hormone Frequency by Progesterone

Phase 1

Recruiting

Conditions: Polycystic Ovary Syndrome
Hyperandrogenism
Normal Puberty

Interventions: Drug: Placebo
Drug: Progesterone

First Posted Date: 2011-09-02

Last Posted Date: 2023-11-02

Lead Sponsor: University of Virginia

Target Recruit Count: 40

Registration Number: NCT01428089

Locations: 🇺🇸
Center for Research in Reproduction, University of Virginia, Charlottesville, Virginia, United States

Effects of Androgen Blockade on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone

Not Applicable

Terminated

Conditions: Hyperandrogenism
Polycystic Ovary Syndrome

Interventions: Drug: Flutamide
Drug: Progesterone
Drug: estrace

First Posted Date: 2011-09-02

Last Posted Date: 2018-06-04

Lead Sponsor: University of Virginia

Target Recruit Count: 4

Registration Number: NCT01428193

Locations: 🇺🇸
Center for Research in Reproduction, University of Virginia, Charlottesville, Virginia, United States

Effect of Metformin on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone

Not Applicable

Completed

Conditions: Polycystic Ovary Syndrome
Hyperandrogenism

Interventions: Drug: Metformin
Drug: Progesterone
Drug: estrace

First Posted Date: 2011-09-01

Last Posted Date: 2021-01-08

Lead Sponsor: University of Virginia

Target Recruit Count: 25

Registration Number: NCT01427595

Locations: 🇺🇸
Center for Research in Reproduction, University of Virginia, Charlottesville, Virginia, United States

Effects of Vitamin D on Renal Blood Flow, Proteinuria and Inflammation in Patients With Chronic Kidney Disease

Not Applicable

Withdrawn

Conditions: Chronic Kidney Disease
Secondary Hyperparathyroidism

First Posted Date: 2011-08-31

Last Posted Date: 2014-05-21

Lead Sponsor: University of Virginia

Registration Number: NCT01426724

Locations: 🇺🇸
University of Virginia, Charlottesville, Virginia, United States

Assessment of the Sensitivity of the Hypothalamic GnRH Pulse Generator to Estradiol and Progesterone Inhibition

Not Applicable

Active, not recruiting

Conditions: Hyperandrogenemia
Polycystic Ovary Syndrome (PCOS)

Interventions: Drug: estrace
Drug: Progesterone

First Posted Date: 2011-08-30

Last Posted Date: 2023-11-02

Lead Sponsor: University of Virginia

Target Recruit Count: 60

Registration Number: NCT01425541

Locations: 🇺🇸
Center for Research in Reproduction, Charlottesville, Virginia, United States

Effect of Spironolactone on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess

Not Applicable

Recruiting

Conditions: Obesity
Hyperandrogenemia
Polycystic Ovary Syndrome

Interventions: Drug: Spironolactone

First Posted Date: 2011-08-24

Last Posted Date: 2023-10-27

Lead Sponsor: University of Virginia

Target Recruit Count: 20

Registration Number: NCT01422759

Locations: 🇺🇸
University of Virginia Center for Research in Reproduction, Charlottesville, Virginia, United States

Effect of Short Term Adrenal Suppression on Androgen Overproduction in Overweight Girls With Androgen Excess

Early Phase 1

Withdrawn

Conditions: Hyperandrogenemia
Obesity
Polycystic Ovary Syndrome

Interventions: Drug: Hydrocortisone

First Posted Date: 2011-08-24

Last Posted Date: 2018-07-19

Lead Sponsor: University of Virginia

Registration Number: NCT01422707

Locations: 🇺🇸
University of Virginia Center for Research in Reproduction, Charlottesville, Virginia, United States

Effect of Longer-term Adrenal Suppression Using Low Dose Hydrocortisone on Androgen Overproduction

Early Phase 1

Withdrawn

Conditions: Obesity
Polycystic Ovary Syndrome
Hyperandrogenemia

Interventions: Drug: Hydrocortisone
Drug: dexamethasone
Drug: Cosyntropin
Drug: rhCG

First Posted Date: 2011-08-24

Last Posted Date: 2018-07-19

Lead Sponsor: University of Virginia

Registration Number: NCT01422733

Locations: 🇺🇸
University of Virginia Center for Research in Reproduction, Charlottesville, Virginia, United States

Effect of Metformin on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess

Early Phase 1

Recruiting

Conditions: Obesity
Hyperandrogenemia
Polycystic Ovary Syndrome

Interventions: Drug: Metformin

First Posted Date: 2011-08-24

Last Posted Date: 2023-10-27

Lead Sponsor: University of Virginia

Target Recruit Count: 20

Registration Number: NCT01422746

Locations: 🇺🇸
University of Virginia Center for Research in Reproduction, Charlottesville, Virginia, United States

Ovarian Contribution to Androgen Production in Adolescent Girls

Not Applicable

Active, not recruiting

Conditions: Polycystic Ovary Syndrome
Obesity
Hyperandrogenism

Interventions: Drug: Dexamethasone
Drug: rhCG

First Posted Date: 2011-08-23

Last Posted Date: 2023-10-27

Lead Sponsor: University of Virginia

Target Recruit Count: 80

Registration Number: NCT01421810

Locations: 🇺🇸
University of Virginia Center for Research in Reproduction, Charlottesville, Virginia, United States

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