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Tempest Therapeutics

🇺🇸United States
Ownership
Public
Employees
17
Market Cap
$33.7M
Website
http://www.tempesttx.com
Introduction

Tempest Therapeutics, Inc. is a clinical-stage oncology company, which engages in the development and discovery of small molecule drugs for the treatment of cancer. The company was founded in 2011 and is headquartered in Brisbane, CA.

A Study of TPST-1120 With Atezolizumab Plus Bevacizumab in Patients With Unresectable or Metastatic HCC Not Previously Treated With Systemic Therapy

Phase 3
Not yet recruiting
Conditions
Hepatocellular Carcinoma (HCC)
Interventions
First Posted Date
2024-11-08
Last Posted Date
2024-11-08
Lead Sponsor
Tempest Therapeutics
Target Recruit Count
740
Registration Number
NCT06680258

Phase 1a/1b Study of TPST-1495 as a Single Agent and in Combination With Pembrolizumab in Subjects With Solid Tumors

Phase 1
Active, not recruiting
Conditions
Endometrial Cancer
Gastric Adenocarcinoma
Solid Tumor
Colorectal Cancer
Squamous Cell Carcinoma of Head and Neck
Non Small Cell Lung Cancer
Urothelial Carcinoma
Solid Tumors With PIK3Ca Mutation
Gastroesophageal Junction Adenocarcinoma
Interventions
Drug: TPST-1495 once daily or on intermittent schedule
Drug: TPST-1495 twice daily
First Posted Date
2020-04-14
Last Posted Date
2024-10-16
Lead Sponsor
Tempest Therapeutics
Target Recruit Count
175
Registration Number
NCT04344795
Locations
🇺🇸

University of Colorado, Aurora, Colorado, United States

🇺🇸

Baystate Gynecologic Oncology, Springfield, Massachusetts, United States

🇺🇸

University of Michigan Rogel Cancer Center, Ann Arbor, Michigan, United States

and more 8 locations

TPST-1120 as Monotherapy and in Combination With Nivolumab in Subjects With Advanced Cancers

Phase 1
Completed
Conditions
Metastatic Castration Resistant Prostate Cancer
Non-small Cell Lung Cancer
Triple-Negative Breast Cancer
Pancreatic Cancer
Colorectal Cancer
Squamous Cell Carcinoma of Head and Neck
Cholangiocarcinoma
Hepatocellular Carcinoma
Urothelial Carcinoma
GastroEsophageal Cancer
Interventions
Drug: Part 1 TPST-1120
Drug: Part 2 TPST-1120 + nivolumab
Drug: Part 3 TPST-1120
Drug: Part 4 TPST-1120 + nivolumab
First Posted Date
2019-02-04
Last Posted Date
2023-07-03
Lead Sponsor
Tempest Therapeutics
Target Recruit Count
38
Registration Number
NCT03829436
Locations
🇺🇸

University of Michigan Rogel Cancer Center, Ann Arbor, Michigan, United States

🇺🇸

Miami Cancer Institute, Miami, Florida, United States

🇺🇸

University of California - San Francisco, San Francisco, California, United States

and more 8 locations
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