Chimerix

πŸ‡ΊπŸ‡ΈUnited States
Ownership
-
Employees
72
Market Cap
$88M
Website
Introduction

Chimerix, Inc. is a biopharmaceutical company, which engages in the research, development, and commercialization of pharmaceutical products. Its portfolio includes Brincidofovir for the treatment of adenovirus, cytomegalovirus, and smallpox. The company was founded in April 2000 and is headquartered in Durham, NC.

ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)

First Posted Date
2022-10-14
Last Posted Date
2024-12-11
Lead Sponsor
Chimerix
Target Recruit Count
450
Registration Number
NCT05580562
Locations
πŸ‡―πŸ‡΅

National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan

πŸ‡―πŸ‡΅

Kyoto University Hospital, Kyoto, Japan

πŸ‡ΈπŸ‡¬

National Cancer Centre, Singapore, Singapore

and more 147 locations

Safety and Pharmacokinetics of CMX001 in Impaired Hepatic Function and Healthy Subjects

Phase 1
Completed
Conditions
Interventions
First Posted Date
2022-05-26
Last Posted Date
2022-05-26
Lead Sponsor
Chimerix
Target Recruit Count
25
Registration Number
NCT05391724
Locations
πŸ‡ΊπŸ‡Έ

DaVita Clinical Research, Minneapolis, Minnesota, United States

πŸ‡ΊπŸ‡Έ

Elite Research, Miami, Florida, United States

πŸ‡ΊπŸ‡Έ

Orlando Clinical Research Center, Orlando, Florida, United States

Expanded Access Use of ONC201 in a Patient With Diffuse Intrinsic Pontine Gliomas

Conditions
First Posted Date
2022-05-26
Last Posted Date
2022-05-26
Lead Sponsor
Chimerix
Registration Number
NCT05392374
Locations
πŸ‡ΊπŸ‡Έ

Children's Healthcare of Atlanta, Atlanta, Georgia, United States

πŸ‡ΊπŸ‡Έ

Albany Medical Center, Albany, New York, United States

πŸ‡ΊπŸ‡Έ

University of California San Francisco, San Francisco, California, United States

and more 7 locations

Intermediate-size Expanded Access to ONC201 for Patients With H3 K27M-mutant and/or Midline Gliomas

Conditions
First Posted Date
2020-11-05
Last Posted Date
2024-08-05
Lead Sponsor
Chimerix
Registration Number
NCT04617002
Locations
πŸ‡ΊπŸ‡Έ

Kaiser Permanente Los Angeles Medical Center, Los Angeles, California, United States

πŸ‡ΊπŸ‡Έ

Providence Saint John's Health Center, Santa Monica, California, United States

πŸ‡ΊπŸ‡Έ

Albany Medical Center, Albany, New York, United States

and more 22 locations

Dociparstat in Combination With Standard Chemotherapy for the Treatment of Acute Myeloid Leukemia

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2020-10-01
Last Posted Date
2024-04-15
Lead Sponsor
Chimerix
Target Recruit Count
9
Registration Number
NCT04571645
Locations
πŸ‡ΊπŸ‡Έ

East Carolina University Vidant Medical Center, Greenville, North Carolina, United States

πŸ‡ΊπŸ‡Έ

Spartanburg Medical Gibbs Cancer Center, Spartanburg, South Carolina, United States

πŸ‡ΊπŸ‡Έ

Baylor, Dallas, Texas, United States

and more 11 locations

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

First Posted Date
2020-09-09
Last Posted Date
2024-04-22
Lead Sponsor
Chimerix
Target Recruit Count
102
Registration Number
NCT04541082
Locations
πŸ‡ΊπŸ‡Έ

National Institutes of Health, Bethesda, Maryland, United States

Dociparstat for the Treatment of Severe COVID-19 in Adults at High Risk of Respiratory Failure

First Posted Date
2020-05-15
Last Posted Date
2022-08-30
Lead Sponsor
Chimerix
Target Recruit Count
27
Registration Number
NCT04389840
Locations
πŸ‡ΊπŸ‡Έ

Advanced Pulmonary Research Institute/Wellington Regional Medical Center, Loxahatchee Groves, Florida, United States

πŸ‡ΊπŸ‡Έ

William Beaumont Hospital, Royal Oak, Michigan, United States

πŸ‡ΊπŸ‡Έ

Augusta University, Augusta, Georgia, United States

and more 9 locations

Incidence and Outcomes Associated With the Management of Adenovirus Infections in Allogenic Hematopoietic Cell Transplant Recipients

Completed
Conditions
First Posted Date
2020-02-26
Last Posted Date
2022-03-25
Lead Sponsor
Chimerix
Target Recruit Count
216
Registration Number
NCT04285788

An Open-Label Study , Safety and Tolerability of Brincidofovir for Post Exposure Prophylaxis of Ebola

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2020-02-13
Last Posted Date
2020-02-26
Lead Sponsor
Chimerix
Registration Number
NCT04268966

Open Label Study of IV Brincidofovir in Adult Transplant Recipients With Adenovirus Viremia

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2018-05-22
Last Posted Date
2021-07-21
Lead Sponsor
Chimerix
Registration Number
NCT03532035
Locations
πŸ‡ΊπŸ‡Έ

Brigham and Womens Hospital, Boston, Massachusetts, United States

πŸ‡ΊπŸ‡Έ

MD Anderson Cancer Center, Houston, Texas, United States

πŸ‡ΊπŸ‡Έ

University of Chigago, Chicago, Illinois, United States

and more 5 locations
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