Kartos Therapeutics, Inc.

Kartos Therapeutics, Inc. logo
🇺🇸United States
Ownership
Holding
Established
2018-01-01
Employees
11
Market Cap
-
Website
http://www.kartosthera.com

Study of Navtemadlin Add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients with Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

First Posted Date
2024-06-28
Last Posted Date
2024-10-30
Lead Sponsor
Kartos Therapeutics, Inc.
Target Recruit Count
600
Registration Number
NCT06479135
Locations
🇺🇸

Mission Cancer + Blood, Des Moines, Iowa, United States

🇺🇸

Norton Cancer Institute, Louisville, Kentucky, United States

🇺🇸

Mary Bird Perkins Cancer Center, Baton Rouge, Louisiana, United States

and more 27 locations

Study of Navtemadlin as Maintenance Therapy in TP53WT Advanced or Recurrent Endometrial Cancer

Phase 2
Recruiting
Conditions
Interventions
First Posted Date
2023-04-04
Last Posted Date
2024-05-02
Lead Sponsor
Kartos Therapeutics, Inc.
Target Recruit Count
268
Registration Number
NCT05797831
Locations
🇺🇸

Indiana University, Indianapolis, Indiana, United States

🇺🇸

Texas Oncology-San Antonio Medical Center, San Antonio, Texas, United States

🇺🇸

Kaiser Permanente Center, Vallejo, California, United States

and more 80 locations

KRT-232 in Subjects With Relapsed or Refractory Small Cell Lung Cancer

First Posted Date
2021-08-30
Last Posted Date
2023-08-16
Lead Sponsor
Kartos Therapeutics, Inc.
Target Recruit Count
3
Registration Number
NCT05027867
Locations
🇪🇸

Hospital Universitario La Paz, Madrid, Spain

🇫🇷

EDOG - Institut Bergonie - PPDS, Bordeaux, France

🇪🇸

Hospital General Universitario de Alicante, Alicante, Spain

and more 30 locations

Study of KRT-232 or TL-895 in Janus Associated Kinase Inhibitor Treatment-Naïve Myelofibrosis

First Posted Date
2021-05-07
Last Posted Date
2022-05-09
Lead Sponsor
Kartos Therapeutics, Inc.
Target Recruit Count
52
Registration Number
NCT04878003
Locations
🇺🇸

Innovative Clinical Research Institute, Whittier, California, United States

🇺🇦

City Hematology Center of Municipal Non-Profit Enterprise City Clinical Hospital #4 of Dnipro City Council, Dnipro, Ukraine

🇧🇾

Minsk Scientific and Practice Center of Surgery, Transplantology and Hematology, Minsk, Belarus

and more 25 locations

KRT-232 and TKI Study in Chronic Myeloid Leukemia

First Posted Date
2021-04-08
Last Posted Date
2022-03-21
Lead Sponsor
Kartos Therapeutics, Inc.
Target Recruit Count
109
Registration Number
NCT04835584
Locations
🇺🇸

University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States

🇮🇹

Azienda Ospedaliero - Universitaria Mater Domini, Catanzaro, Italy

🇮🇹

Fondazione IRCCS Policlinico San Matteo, Pavia, Italy

and more 23 locations

KRT-232 in Combination With TL-895 for the Treatment of R/R MF and KRT-232 for the Treatment of JAKi Intolerant MF

First Posted Date
2020-11-23
Last Posted Date
2022-05-09
Lead Sponsor
Kartos Therapeutics, Inc.
Target Recruit Count
116
Registration Number
NCT04640532
Locations
🇫🇷

CHU Nantes - Hôtel Dieu, Nantes, France

🇭🇺

Medical Center of the University of Pecs, 1st Department of Internal Medicine, Division of Hematology, Pécs, Hungary

🇵🇱

Nasz Lekarz Medical Outpatient Clinics Slawomir Jeka, Toruń, Poland

and more 34 locations

Safety and Efficacy of KRT-232 in Combination With Acalabrutinib in Subjects With R/R DLBCL or R/R CLL

First Posted Date
2020-08-06
Last Posted Date
2022-08-04
Lead Sponsor
Kartos Therapeutics, Inc.
Target Recruit Count
84
Registration Number
NCT04502394
Locations
🇰🇷

Seoul St. Mary's Hospital, Seoul, Korea, Republic of

🇵🇱

Uniwersyteckie Centrum Kliniczne, Klinika Hematologii i Transplantologii, Gdansk, Poland

🇵🇱

Copernicus PL Sp. z o.o., Wojewodzkie Centrum Onkologii, Gdańsk, Poland

and more 42 locations

An Open-Label, Multicenter, Phase 1b/2 Study of the Safety and Efficacy of KRT-232 Combined With Ruxolitinib in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera MF (Post-PV-MF), Or Post-Essential Thrombocythemia MF (Post ET-MF) Who Have a Suboptimal Response to Ruxolitinib

Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2020-07-24
Last Posted Date
2022-05-09
Lead Sponsor
Kartos Therapeutics, Inc.
Target Recruit Count
36
Registration Number
NCT04485260
Locations
🇫🇷

Institut Paoli-Calmettes, Marseille, France

🇵🇱

Oddział Kliniczny Hematologii Szpitala Uniwersyteckiego w Krakowie, Kraków, Poland

🇵🇱

Szpital Wojewódzki w Opolu Sp zooOddzial Kliniczny Hematologii, Opole, Poland

and more 35 locations

An Open-Label, Multicenter, Phase 1b/2 Study of the Safety and Efficacy of KRT-232 When Administered Alone and in Combination With Low-Dose Cytarabine (LDAC) or Decitabine in Patients With Acute Myeloid Leukemia (AML)

First Posted Date
2019-10-03
Last Posted Date
2024-03-22
Lead Sponsor
Kartos Therapeutics, Inc.
Target Recruit Count
70
Registration Number
NCT04113616
Locations
🇩🇪

University Hospital Jena, Jena, Germany

🇧🇪

Cliniques universitaires Saint-Luc, Brussels, Belgium

🇧🇪

UZ Gent, Ghent, Belgium

and more 55 locations
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