CHILDREN'S HOSPITAL OF PHILADELPHIA

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1855-01-01

Employees: -

Market Cap: -

Website: http://www.chop.edu/

Clinical Trials

Smart Checklist Implementation for Pediatric Tracheal Intubations in the ICU- Multicenter Study

Not Applicable

Recruiting

Conditions: Intubation Complication

Interventions: Other: Smart Checklist

First Posted Date: 2023-10-16

Last Posted Date: 2024-11-12

Lead Sponsor: Children's Hospital of Philadelphia

Target Recruit Count: 3000

Registration Number: NCT06085326

Locations: 🇺🇸
University of Arkansas, Little Rock, Arkansas, United States
🇺🇸
University of Virginia, Charlottesville, Virginia, United States
🇺🇸
University of Nebraska Medical Center, Omaha, Nebraska, United States

and more 3 locations

Helping Educate and Advance Learning Through Healthy Bite-Sized Eating Strategies

Not Applicable

Recruiting

Conditions: Adolescent Obesity
Diet, Healthy
Adolescent Overweight

Interventions: Behavioral: Intervention

First Posted Date: 2023-10-13

Last Posted Date: 2024-11-28

Lead Sponsor: Children's Hospital of Philadelphia

Target Recruit Count: 70

Registration Number: NCT06082830

Locations: 🇺🇸
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

Promoting Resilience in Stress Management (PRISM) and Clinical-focused Narrative (CFN) Pilot in Adults With Primary Mitochondrial Disease (PMD).

Phase 1

Completed

Conditions: Mitochondrial Myopathies
Mitochondrial Encephalomyopathies
Mitochondrial Diseases
MELAS
MERRF

Interventions: Behavioral: Promoting Resilience in Stress Management (PRISM)
Behavioral: Clinical-focused narrative (CFN)

First Posted Date: 2023-09-25

Last Posted Date: 2024-11-29

Lead Sponsor: Children's Hospital of Philadelphia

Target Recruit Count: 16

Registration Number: NCT06051448

Locations: 🇺🇸
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

Using Electronically Derived Automated Reports of Appropriate Antibiotic Use to Inform Stewardship Interventions

Not Applicable

Recruiting

Conditions: Acute Otitis Media
Community-acquired Pneumonia
Pharyngitis

Interventions: Behavioral: Mixed methods intervention

First Posted Date: 2023-09-07

Last Posted Date: 2023-09-07

Lead Sponsor: Children's Hospital of Philadelphia

Target Recruit Count: 511000

Registration Number: NCT06027593

Locations: 🇺🇸
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
🇺🇸
University of Pennsylvania Health System, Philadelphia, Pennsylvania, United States

Reducing Empiric VAncomycin Use in Pediatric Suspected Sepsis

Not Applicable

Recruiting

Conditions: Sepsis Mrsa
Sepsis
Antimicrobial - Induced Nephropathy
Septic Syndrome
Sepsis Bacteremia
Sepsis, Severe
Septic Shock

Interventions: Behavioral: Multifaceted de-implementation strategy to reduce vancomycin overuse

First Posted Date: 2023-08-04

Last Posted Date: 2023-09-13

Lead Sponsor: Children's Hospital of Philadelphia

Target Recruit Count: 52500

Registration Number: NCT05975671

Locations: 🇺🇸
St. Louis Children's Hospital, Saint Louis, Missouri, United States
🇺🇸
Children's Healthcare of Atlanta, Atlanta, Georgia, United States
🇺🇸
Johns Hopkins Children's Center, Baltimore, Maryland, United States

and more 1 locations

Neurophysiologic Biomarkers in Rett Syndrome

Recruiting

Conditions: RTT
Rett Syndrome, Atypical
Rett Syndrome

Interventions: Other: EEG and Auditory and Visual Evoked Potentials (AEP and VEP)
Other: Clinical assessment

First Posted Date: 2023-07-06

Last Posted Date: 2024-11-12

Lead Sponsor: Children's Hospital of Philadelphia

Target Recruit Count: 202

Registration Number: NCT05932589

Locations: 🇺🇸
Children's Hospital of Los Angeles, Los Angeles, California, United States
🇺🇸
Children's Hospital Colorado, Aurora, Colorado, United States
🇺🇸
Boston Children's Hospital, Brookline, Massachusetts, United States

and more 3 locations

COIN: A Pilot Study of Cash Transfers to Improve Outcomes in Low-Income Preterm Neonates and Their Families

Not Applicable

Completed

Conditions: Preterm Birth

Interventions: Other: Unconditional Cash Transfer (Low-Value)
Other: Unconditional Cash Transfer (High-Value)

First Posted Date: 2023-07-05

Last Posted Date: 2024-01-08

Lead Sponsor: Children's Hospital of Philadelphia

Target Recruit Count: 24

Registration Number: NCT05930327

Locations: 🇺🇸
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
🇺🇸
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

Lurbinectedin in FET-Fused Tumors

Phase 1

Recruiting

Conditions: Undifferentiated Sarcoma
Desmoplastic Small Round Cell Tumor
Ewing Sarcoma
Pediatric Cancer

Interventions: Drug: Lurbinectedin

First Posted Date: 2023-06-26

Last Posted Date: 2024-08-14

Lead Sponsor: Children's Hospital of Philadelphia

Target Recruit Count: 56

Registration Number: NCT05918640

Locations: 🇺🇸
Cedars-Sinai Medical Center, Los Angeles, California, United States
🇺🇸
University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States
🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

and more 4 locations

Synovial Sarcoma Registry / Biospecimen Repository

Recruiting

Conditions: Synovial Sarcoma

First Posted Date: 2023-06-18

Last Posted Date: 2024-06-04

Lead Sponsor: Children's Hospital of Philadelphia

Target Recruit Count: 1000

Registration Number: NCT05910307

Locations: 🇺🇸
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

Gastric Volume in Patients on GLP-1 Medications

Recruiting

Conditions: Diabetes

Interventions: Other: None - observational

First Posted Date: 2023-06-15

Last Posted Date: 2024-03-27

Lead Sponsor: Children's Hospital of Philadelphia

Target Recruit Count: 110

Registration Number: NCT05903482

Locations: 🇺🇸
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

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