University of North Carolina - Chapel Hill Endowment Fund

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private, Subsidiary

Employees: -

Market Cap: -

Website

Clinical Trials

North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2

Not Applicable

Completed

Conditions: Development Delay
Epilepsy; Seizure
Brain Malformation
Intellectual Disability
Skeletal Dysplasia
Congenital Abnormality
Macrocephaly
Genetic Disease
Microcephaly
Neuromuscular Diseases

Interventions: Behavioral: Pre-visit prep
Diagnostic Test: usual care + exome seq

First Posted Date: 2018-06-07

Last Posted Date: 2025-05-13

Lead Sponsor: University of North Carolina, Chapel Hill

Target Recruit Count: 548

Registration Number: NCT03548779

Locations: 🇺🇸
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States
🇺🇸
East Carolina University, Greenville, North Carolina, United States
🇺🇸
Mission Health, Asheville, North Carolina, United States

Reducing Binge Eating to Prevent Weight Gain in Black Women

Not Applicable

Terminated

Conditions: Binge Eating
Weight Loss
Weight Gain Prevention

Interventions: Behavioral: Appetite Awareness Treatment + Lifestyle Modification

First Posted Date: 2018-05-21

Last Posted Date: 2021-12-17

Lead Sponsor: University of North Carolina, Chapel Hill

Target Recruit Count: 20

Registration Number: NCT03531112

Locations: 🇺🇸
Nutrition Research Institute, Kannapolis, North Carolina, United States

Late Phase Administration Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation

Phase 1

Withdrawn

Conditions: Asthma

Interventions: Biological: Anakinra
Other: Anakinra Matching Placebo
Drug: Dermatophagoides Farinae

First Posted Date: 2018-05-01

Last Posted Date: 2021-05-14

Lead Sponsor: University of North Carolina, Chapel Hill

Registration Number: NCT03513458

IFI16 is a Periodontitis Modulating Protein

Not Applicable

Completed

Conditions: Severe Periodontitis
Acute Inflammatory Response

Interventions: Other: Customized acrylic mouthguard

First Posted Date: 2018-05-01

Last Posted Date: 2024-07-03

Lead Sponsor: University of North Carolina, Chapel Hill

Target Recruit Count: 69

Registration Number: NCT03513497

Locations: 🇺🇸
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States

Early Phase Administration of Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation

Phase 1

Withdrawn

Conditions: Asthma

Interventions: Biological: Anakinra
Other: Anakinra Matching Placebo
Drug: Dermatophagoides Farinae

First Posted Date: 2018-05-01

Last Posted Date: 2021-05-07

Lead Sponsor: University of North Carolina, Chapel Hill

Registration Number: NCT03513471

Impact of Sugar-Sweetened Beverage Health Warnings

Not Applicable

Completed

Conditions: Dietary Habits

Interventions: Behavioral: Sugar-Sweetened Beverage Health Warning Label
Other: Neutral Label

First Posted Date: 2018-04-30

Last Posted Date: 2021-03-30

Lead Sponsor: University of North Carolina, Chapel Hill

Target Recruit Count: 400

Registration Number: NCT03511937

Locations: 🇺🇸
University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States

Study of Airway Inflammatory Responses to Experimental Rhinovirus Infection

Phase 1

Withdrawn

Conditions: Rhinovirus
Healthy Volunteers

Interventions: Biological: RG-HRV16

First Posted Date: 2018-04-25

Last Posted Date: 2025-06-03

Lead Sponsor: University of North Carolina, Chapel Hill

Target Recruit Count: 23

Registration Number: NCT03508479

Locations: 🇺🇸
UNC Center for Environmental Medicine, Asthma and Lung Biology, Chapel Hill, North Carolina, United States

Nitrous Oxide for External Cephalic Version

Phase 3

Completed

Conditions: External Cephalic Version

Interventions: Drug: Nitrous Oxide
Other: Placebo

First Posted Date: 2018-04-19

Last Posted Date: 2019-10-30

Lead Sponsor: University of North Carolina, Chapel Hill

Target Recruit Count: 48

Registration Number: NCT03502915

Locations: 🇺🇸
University of North Carolina, Chapel Hill, North Carolina, United States

Efficacy of Tetracaine/Oxymetazoline Nasal Spray for Endodontic Treatment

Phase 4

Withdrawn

Conditions: Local Anesthesia
Endodontic Inflammation
Endodontic Disease
Dental Anesthesia

Interventions: Drug: Tetracaine HCl and oxymetazoline HCl nasal spray

First Posted Date: 2018-04-18

Last Posted Date: 2018-11-16

Lead Sponsor: University of North Carolina, Chapel Hill

Registration Number: NCT03502135

19F MRI of Ventilation in Subjects With Cystic Fibrosis Undergoing Treatment for Pulmonary Exacerbation

Early Phase 1

Terminated

Conditions: Cystic Fibrosis

Interventions: Device: Lung Clearance Index
Drug: MRI with PFP

First Posted Date: 2018-04-13

Last Posted Date: 2020-10-09

Lead Sponsor: University of North Carolina, Chapel Hill

Target Recruit Count: 5

Registration Number: NCT03497117

Locations: 🇺🇸
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States

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