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JANSSEN RESEARCH & DEVELOPMENT, LLC

🇺🇸United States
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A Study of CNTO 136 (Sirukumab), a Human Anti-IL-6 Monoclonal Antibody, Administered Subcutaneously, in Patients With Active Rheumatoid Arthritis Despite Anti-TNF-Alpha Therapy (SIRROUND-T)

Phase 3
Completed
Conditions
Arthritis, Rheumatoid
Interventions
Drug: Placebo
First Posted Date
2012-05-28
Last Posted Date
2018-03-23
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
878
Registration Number
NCT01606761

A Study of CNTO 136 (Sirukumab), Administered Subcutaneously, in Patients With Active Rheumatoid Arthritis Despite Disease-Modifying Antirheumatic Drug (DMARD) Therapy (SIRROUND-D)

Phase 3
Completed
Conditions
Arthritis, Rheumatoid
Interventions
Drug: Placebo
First Posted Date
2012-05-23
Last Posted Date
2018-01-11
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
1670
Registration Number
NCT01604343

A Study to Evaluate the Efficacy and Safety of Ibrutinib, in Patients With Mantle Cell Lymphoma Who Progress After Bortezomib Therapy

Phase 2
Completed
Conditions
Mantle Cell Lymphoma
Interventions
First Posted Date
2012-05-16
Last Posted Date
2016-06-01
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
120
Registration Number
NCT01599949

A Study of JNJ-40346527 in Patients With Active Rheumatoid Arthritis Despite Disease-modifying Antirheumatic Drug Therapy

Phase 2
Completed
Conditions
Arthritis, Rheumatoid
Interventions
Drug: Placebo
First Posted Date
2012-05-14
Last Posted Date
2014-04-08
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
96
Registration Number
NCT01597739

Study of Abiraterone Acetate Plus Prednisone in Patients With Chemo-naive Metastatic Castration-Resistant Prostate Cancer

Phase 3
Completed
Conditions
Prostate Cancer
Interventions
First Posted Date
2012-05-03
Last Posted Date
2020-01-21
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
313
Registration Number
NCT01591122

A Study to Assess the Effect of Ketoconazole on the Pharmacokinetics of Abiraterone Following Administration of Abiraterone Acetate Tablets in Healthy Adult Men

Phase 1
Completed
Conditions
Healthy Volunteers
First Posted Date
2012-05-01
Last Posted Date
2012-11-27
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
20
Registration Number
NCT01588782

A Study of JNJ-40411813 as Supplementary Treatment to an Antidepressant in Adults With Depression and Anxiety Symptoms

Phase 2
Completed
Conditions
Major Depressive Disorder
Interventions
Drug: Placebo
First Posted Date
2012-04-23
Last Posted Date
2015-06-16
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
121
Registration Number
NCT01582815

A Study of JNJ-40346527 in Patients With Relapsed or Refractory Hodgkin Lymphoma

Phase 1
Completed
Conditions
Relapsed or Refractory Hodgkin Lymphoma
Interventions
Drug: Phase 1, Cohort 1
Drug: Phase 1, Cohort 2
Drug: Phase 1, Cohort 3
Drug: Phase 1, Cohort 4
Drug: Phase 2
First Posted Date
2012-04-06
Last Posted Date
2020-11-20
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
21
Registration Number
NCT01572519

A Study Combining Ibrutinib With Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Patients With CD20-Positive B-Cell Non Hodgkin Lymphoma

Phase 1
Completed
Conditions
CD20-positive B-cell Non-Hodgkin Lymphoma
Interventions
Drug: Part 1, Cohort 1
Drug: Part 1, Cohort 2
Drug: Part 1, Cohort 3
Drug: Part 2, Cohort 1
Drug: Part 2, Cohort 2
First Posted Date
2012-04-03
Last Posted Date
2017-08-22
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
33
Registration Number
NCT01569750
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