Clinical Trials
5
Trial Phases
3 Phases
Drug Approvals
0
Drug Approvals
No drug approvals found
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Clinical Trials
Distribution across different clinical trial phases (5 trials with phase data)• Click on a phase to view related trials
Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
- Conditions
- Metastatic Breast Cancer
- Interventions
- First Posted Date
- 2023-01-25
- Last Posted Date
- 2025-11-06
- Lead Sponsor
- Sermonix Pharmaceuticals Inc.
- Target Recruit Count
- 500
- Registration Number
- NCT05696626
- Locations
- 🇺🇸
Cleveland Clinic, Cleveland, Ohio, United States
🇨🇳Nanchang People's Hospital, Nanchang, China
🇬🇧University Hospital of North Tees, Stockton-on-Tees, United Kingdom
Evaluation of Lasofoxifene Combined With Abemaciclib in Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
- Conditions
- Metastatic Breast Cancer
- Interventions
- First Posted Date
- 2020-06-16
- Last Posted Date
- 2025-02-13
- Lead Sponsor
- Sermonix Pharmaceuticals Inc.
- Target Recruit Count
- 29
- Registration Number
- NCT04432454
- Locations
- 🇺🇸
University of Alabama at Birmingham (UAB) - Comprehensive Cancer Center, Birmingham, Alabama, United States
🇺🇸Yuma Regional Medical Center, Yuma, Arizona, United States
🇺🇸Compassionate Cancer Care Med Group - Clinic Aid USA - Fountain Valley, Fountain Valley, California, United States
Evaluation of Lasofoxifene Versus Fulvestrant in Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
- Conditions
- Locally Advanced or Metastatic Breast Cancer
- Interventions
- First Posted Date
- 2018-12-19
- Last Posted Date
- 2024-04-18
- Lead Sponsor
- Sermonix Pharmaceuticals Inc.
- Target Recruit Count
- 100
- Registration Number
- NCT03781063
- Locations
- 🇺🇸
Mayo Clinic Arizona, Phoenix, Arizona, United States
🇺🇸Yuma Regional Medical Center (JIT), Yuma, Arizona, United States
🇺🇸City of Hope Comprehensive Cancer, Duarte, California, United States
News
Lasofoxifene Shows Promise in Early Breast Cancer Treatment, I-SPY 2 Trial Data Reveal
Lasofoxifene demonstrates a strong tolerability profile and promising Ki67 suppression in a Phase 2 study, supporting further exploration in the neoadjuvant setting.