MedPath

ZAMBON SPA

🇮🇹Italy
Ownership
Subsidiary
Employees
-
Market Cap
-
Website
http://www.zambon.com

Clinical Trials

44

Active:21
Completed:20

Trial Phases

5 Phases

Phase 1:26
Phase 2:3
Phase 3:10
+2 more phases

Drug Approvals

1

EMA:1

Drug Approvals

Xadago

Authorization Status
Authorised
Approval Date
Feb 23, 2015
EMA

Clinical Trials

Distribution across different clinical trial phases (41 trials with phase data)• Click on a phase to view related trials

Phase 1
26 (63.4%)
Phase 3
10 (24.4%)
Phase 2
3 (7.3%)
Not Applicable
1 (2.4%)
Phase 4
1 (2.4%)

A Retrospective Chart Review Study of Patients With Chronic Lung Allograft Dysfunction-Bronchiolitis Obliterans Syndrome (CLAD-BOS) Post Lung Transplantation

Completed
Conditions
Bronchiolitis Obliterans Syndrome Due to and After Lung Transplantation (Disorder)
First Posted Date
2024-07-16
Last Posted Date
2025-05-20
Lead Sponsor
Zambon SpA
Target Recruit Count
284
Registration Number
NCT06503770
Locations
🇺🇸

Cleveland Clinic Main Campus, Cleveland, Ohio, United States

🇺🇸

Baylor Scott and White Health Advanced Lung Disease Specialists, Dallas, Texas, United States

🇧🇪

Universitaire Ziekenhuizen Leuven (UZ Leuven) Campus Gasthuisberg, Leuven, Belgium

and more 2 locations

Phase 1 Three Part SAD, MAD & Cross-Over Study of ZP-059 in Healthy and Asthmatic Subjects

Phase 1
Completed
Conditions
Allergic Bronchopulmonary Aspergillosis
Interventions
First Posted Date
2020-01-18
Last Posted Date
2021-11-15
Lead Sponsor
Zambon SpA
Target Recruit Count
58
Registration Number
NCT04229303
Locations
🇬🇧

Medicines Evaluation Unit Ltd. (MEU), Manchester, United Kingdom

A Safety Study of Liposomal Cyclosporine A to Treat Bronchiolitis After Hematopoietic Transplant (BOSTON-4)

Phase 2
Terminated
Conditions
Bronchiolitis Obliterans Syndrome (BOS)
Stem Cell Transplant Complications
GVHD, Chronic
Interventions
Drug: Liposomal Placebo
First Posted Date
2019-09-27
Last Posted Date
2023-10-03
Lead Sponsor
Zambon SpA
Target Recruit Count
6
Registration Number
NCT04107675
Locations
🇫🇷

CHU Hôpital Sud, Amiens, France

🇫🇷

Centre Hospitalier Universitaire d'Angers, Angers, France

🇫🇷

Centre Hospitalier Universitaire Grenoble Alpes - Hopital Albert Michallon, La Tronche, France

and more 14 locations

Extension Trial on Efficacy / Safety of L-CsA + SoC in Treating BOS in Post Single or Double Lung Transplant (BOSTON-3)

Phase 3
Active, not recruiting
Conditions
Bronchiolitis Obliterans
Obliterative Bronchiolitis
Bronchiolitis Obliterans Syndrome
Interventions
Drug: Liposomal Cyclosporine A 5 mg
Drug: Liposomal Cyclosporine A 10 mg
First Posted Date
2019-07-31
Last Posted Date
2025-01-27
Lead Sponsor
Zambon SpA
Target Recruit Count
262
Registration Number
NCT04039347
Locations
🇺🇸

Banner - University Medical Center, Phoenix, Arizona, United States

🇺🇸

David Geffen School of Medicine at UCLA, Los Angeles, California, United States

🇺🇸

UCSF, San Francisco, California, United States

and more 34 locations

An Observational Study on Safinamide, Rasagiline and Other Standard of Care in PD

Completed
Conditions
Parkinson's Disease
First Posted Date
2019-06-21
Last Posted Date
2024-04-11
Lead Sponsor
Zambon SpA
Target Recruit Count
1235
Registration Number
NCT03994328
Locations
🇩🇪

Praxis Dr. med. Kirsten Hahn, Berlin, Germany

🇮🇹

Università degli Studi G. D'Annunzio, Chieti, Italy

🇪🇸

Corporacio Sanitaria Parc Tauli, Sabadell, Spain

  • Prev
  • 1
  • 2
  • 3
  • 4
  • 5
  • Next

News

NCFB Pipeline Shows Promise with Over 15 Companies Developing New Therapies

• The non-cystic fibrosis bronchiectasis (NCFB) market is experiencing growth due to rising prevalence and increased awareness, leading to early diagnosis and treatment. • Over 15 companies are actively developing more than 15 NCFB drugs, aiming to improve the treatment landscape for this chronic lung condition. • Key players like Insmed, AstraZeneca, and Verona Pharma are advancing promising therapies such as brensocatib, benralizumab and ensifentrine through clinical trials. • Recent clinical trial milestones, including Phase III results for brensocatib and Phase II enrollment for AP-PA02, signal progress in addressing unmet needs in NCFB treatment.

© Copyright 2025. All Rights Reserved by MedPath