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Voriconazole

Generic Name
Voriconazole
Brand Names
Vfend, Voriconazole Hikma (previously Voriconazole Hospira), Voriconazole Accord
Drug Type
Small Molecule
Chemical Formula
C16H14F3N5O
CAS Number
137234-62-9
Unique Ingredient Identifier
JFU09I87TR

Overview

Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised. These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. The increased affinity of voriconazole for 14-alpha sterol demethylase makes it useful against some fluconazole-resistant organisms. Voriconazole was approved by the FDA under the trade name Vfend on May 24, 2002.

Background

Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised. These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. The increased affinity of voriconazole for 14-alpha sterol demethylase makes it useful against some fluconazole-resistant organisms. Voriconazole was approved by the FDA under the trade name Vfend on May 24, 2002.

Indication

For the treatment of esophageal candidiasis, cadidemia, invasive pulmonary aspergillosis, and serious fungal infections caused by Scedosporium apiospermum and Fusarium spp.

Associated Conditions

  • Aspergillosis of the Central Nervous System
  • Aspergillosis of the Liver
  • Candidemia
  • Candidiasis
  • Coccidioidomycosis
  • Endocarditis caused by Aspergillus
  • Esophageal Candidiasis
  • Fungal Infections
  • Fungal meningitis caused by Exserohilum Infection
  • Fusarium infection
  • Histoplasmosis
  • Invasive Aspergillosis
  • Osteomyelitis caused by Aspergillus
  • Penicillium marneffei infection
  • Peritonitis caused by Aspergillus
  • Scedosporium Infection
  • Sinusitis aspergillus
  • Aspergillus endophthalmitis
  • Refractory Oral Candidiasis

FDA Approved Products

VFEND
Manufacturer:Roerig
Route:INTRAVENOUS
Strength:10 mg in 1 mL
Approved: 2022/08/15
NDC:0049-3190
voriconazole
Manufacturer:Golden State Medical Supply, Inc.
Route:ORAL
Strength:200 mg in 1 1
Approved: 2024/02/26
NDC:51407-133
voriconazole
Manufacturer:Novel Laboratories, Inc.
Route:ORAL
Strength:50 mg in 1 1
Approved: 2019/12/20
NDC:40032-088
voriconazole
Manufacturer:Novel Laboratories, Inc.
Route:ORAL
Strength:200 mg in 1 1
Approved: 2019/12/20
NDC:40032-089
voriconazole
Manufacturer:Zydus Lifesciences Limited
Route:ORAL
Strength:50 mg in 1 1
Approved: 2024/02/14
NDC:65841-830

Singapore Approved Products

VORICONAZOLE SANDOZ FILM COATED TABLET 200MG
Manufacturer:Sandoz Private Limited
Form:TABLET, FILM COATED
Strength:200mg
Online:Yes
Approved: 2015/10/06
Approval:SIN14859P
VFEND FILM-COATED TABLET 50 mg
Manufacturer:R-Pharm Germany GmbH, Pfizer Italia S.r.l.
Form:TABLET, FILM COATED
Strength:50 mg
Online:Yes
Approved: 2003/08/05
Approval:SIN12378P
Vfend Powder for Oral Suspension 40mg/ml
Manufacturer:FAREVA AMBOISE
Form:POWDER, FOR SUSPENSION
Strength:40mg/ml
Online:Yes
Approved: 2004/10/28
Approval:SIN13033P
VORICA VORICONAZOLE POWDER FOR SOLUTION FOR INFUSION 200MG/VIAL
Manufacturer:ASPIRO PHARMA LIMITED
Form:INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Strength:200 mg/vial
Online:Yes
Approved: 2022/01/10
Approval:SIN16417P
VORITROP 50 FILM COATED TABLET 50 MG
Manufacturer:INTAS PHARMACEUTICALS LIMITED
Form:TABLET, FILM COATED
Strength:50 mg
Online:Yes
Approved: 2019/11/01
Approval:SIN15848P

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