IMPACT-AML: A Randomized Pragmatic Clinical Trial for Relapsed or Refractory Acute Myeloid Leukemia.
- Conditions
- Acute Myeloid LeukemiaRelapse/Recurrence
- Interventions
- Drug: Low intensity therapiesDrug: High intensity therapies
- First Posted Date
- 2024-12-03
- Last Posted Date
- 2025-05-31
- Target Recruit Count
- 339
- Registration Number
- NCT06713837
- Locations
- 🇨🇿
University Hospital Brno, Brno, Czechia
🇨🇿University Hospital Hradec Králové, Hradec Králové, Czechia
🇨🇿University Hospital Olomouc, Olomouc, Czechia
Sequential Immunochemotherapy Treatment with Pembrolizumab Plus Dendritic Cell (DC) Vaccine Followed by Trifluridine/Tipiracil Plus Bevacizumab in Refractory Mismatch-repair-proficient (pMMR) or Microsatellite-stable (MSS) Metastatic Colorectal Cancer
- Conditions
- Microsatellite Stable Colorectal CarcinomaRefractory Mismatch-repair-proficient (pMMR) Metastatic Colorectal CancerColorectal Cancer Metastatic
- Interventions
- Biological: Autologous Dendritic Cell (DC) Vaccine
- First Posted Date
- 2024-07-26
- Last Posted Date
- 2025-01-28
- Target Recruit Count
- 36
- Registration Number
- NCT06522919
- Locations
- 🇮🇹
IRCCS Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori"-IRST S.r.l., Meldola, Forlì Cesena, Italy
🇮🇹Pia Fondazione di Culto e Religione Azienda Ospedaliera "Card.G.Panico", Tricase, Lecce, Italy
Master Framework For Relapse or Refractory Acute Myeloid Leukemia
- Conditions
- Acute Myeloid Leukemia, in RelapseAcute Myeloid Leukemia Refractory
- Interventions
- Other: Registration into the STREAM platform
- First Posted Date
- 2024-06-14
- Last Posted Date
- 2025-05-31
- Target Recruit Count
- 4000
- Registration Number
- NCT06459024
- Locations
- 🇩🇪
University Hospital Greifswald, Greifswald, Germany
🇩🇪University Hospital Halle, Halle, Germany
🇩🇪University Hospital of Rostock, Rostock, Germany
Avidination for RadionuclideTHerapy in Nonpalpable Breast Cancer
- First Posted Date
- 2024-04-30
- Last Posted Date
- 2025-02-03
- Target Recruit Count
- 18
- Registration Number
- NCT06390241
- Locations
- 🇮🇹
IRCCS Istituto ROmagnolo per lo Studio dei Tumori "Dino Amadori"-IRST S.r.l., Meldola, Forlì Cesena, Italy
National Database of Bone Metastases
- Conditions
- Bone Metastases
- Interventions
- Other: Registration in a database
- First Posted Date
- 2024-04-16
- Last Posted Date
- 2024-04-16
- Target Recruit Count
- 800
- Registration Number
- NCT06367491
- Locations
- 🇮🇹
A.U.S.L. Imola, Imola, Bologna, Italy
🇮🇹Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola, FC, Italy
🇮🇹Osp. "Sacro Cuore di Gesù", Gallipoli, Lecce, Italy
68 Gallium-Fibroblast Activating Protein Inhibitors-46 Positron Emission Tomography - Computerized Tomography for Molecular Assessment of Fibroblast Activation and Risk Assessment in Solid Tumors
- Conditions
- Solid Tumor, Unspecified, Adult
- Interventions
- Diagnostic Test: 68 Gallium -Fibroblast Activating Protein Inhibitor -46 Positron emission tomography / Computerized tomography
- First Posted Date
- 2023-11-18
- Last Posted Date
- 2024-06-04
- Target Recruit Count
- 100
- Registration Number
- NCT06136065
- Locations
- 🇮🇹
IRCCS Istituto ROmagnolo per lo Studio dei Tumori "Dino Amadori"-IRST S.r.l., Meldola, Forlì Cesena, Italy
🇮🇹Azienda USL Toscana Centro - SOC Medicina Nucleare - Nuovo Ospedale "Santo Stefano", Prato, Italy
"Receptor Radionuclide Therapy With 177Lu-DOTATOC
- Conditions
- Neuroendocrine TumorsParagangliomaPheochromocytoma
- Interventions
- First Posted Date
- 2023-09-21
- Last Posted Date
- 2024-08-13
- Target Recruit Count
- 100
- Registration Number
- NCT06045260
- Locations
- 🇮🇹
AUSL Romagna - Ospedale "M. Bufalini", Cesena, Forlì-Cesena, Italy
🇮🇹IRCCS Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST S.r.l., Meldola, Forlì-Cesena, Italy
A phase II randomized trial of Lu-PSMA and Stereotactic Radiotherapy versus Radiotherapy alone for oligometastatic prostate cancer (LUST)
- Conditions
- Oligometastatic prostate carcinoma
- Interventions
- Drug: [177Lu]Lu-PSMA I&TRadiation: Stereotactic Radiotherapy
- First Posted Date
- 2025-01-15
- Last Posted Date
- 2025-01-15
- Target Recruit Count
- 70
- Registration Number
- 2024-519347-15-00
- Locations
- 🇮🇹
Istituto Romagnolo Per Lo Studio Dei Tumori Dino Amadori IRST S.r.l., Meldola, Italy
🇮🇹Azienda Unita Sanitaria Locale Della Romagna, Cesena, Italy
Radiometabolic Therapy With 177Lu PSMA in PSMA PET/CT Positive Advanced/Metastatic Tumours:
- Conditions
- Cancer
- Interventions
- Drug: [177Lu]Lu-PSMA I&T
- First Posted Date
- 2023-05-22
- Last Posted Date
- 2025-06-12
- Target Recruit Count
- 83
- Registration Number
- NCT05867615
- Locations
- 🇮🇹
UO Medicina Nucleare, IRCCS IRST, Meldola, Forlì, Italy
🇮🇹UO Medicina Nucleare, AUSL della Romagna, Cesena, Italy
GEM+Nab-Paclitaxel Plus Losartan Followed by Stereotactic Radiotherapy for Locally Advanced Pancreatic Cancer
- Conditions
- Pancreatic Cancer
- Interventions
- First Posted Date
- 2023-05-16
- Last Posted Date
- 2024-12-27
- Target Recruit Count
- 34
- Registration Number
- NCT05861336
- Locations
- 🇮🇹
U.O. Radioterapia IRCCS IRST, Meldola, Forlì, Italy
🇮🇹UO Oncologia, AUSL della Romagna, Ravenna, Italy