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Quince Therapeutics

Quince Therapeutics logo
🇺🇸United States
Ownership
Public
Established
2012-01-01
Employees
32
Market Cap
$29.8M
Website
http://quincetx.com
Introduction

Quince Therapeutics, Inc.(formerly Cortexyme, Inc.) is a biopharmaceutical company, which engages in the development and commercialization of therapeutics. Its pipeline composed of COR388, COR588, COR788, COR822, and Coronavirus 3CL protease inhibitor. The company was founded by Casey Crawford Lynch, Stephen Dominy, and Kristen Gafric on June 20, 2012 and is headquartered in South San Francisco, CA.

Clinical Trials

10

Active:0
Completed:5

Trial Phases

3 Phases

Phase 1:3
Phase 2:1
Phase 3:5

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (9 trials with phase data)• Click on a phase to view related trials

Phase 3
5 (55.6%)
Phase 1
3 (33.3%)
Phase 2
1 (11.1%)

Open-Label Extension of EryDex Study IEDAT-04-2022

Phase 3
Recruiting
Conditions
Ataxia Telangiectasia
Interventions
First Posted Date
2024-10-30
Last Posted Date
2025-07-01
Lead Sponsor
Quince Therapeutics S.p.A.
Target Recruit Count
106
Registration Number
NCT06664853
Locations
🇺🇸

University of California Los Angeles (UCLA), Ataxia Center and HD Center of excellence, Los Angeles, California, United States

🇺🇸

The Johns Hopkins Hospital, Division of pediatric allergy and immunology, Baltimore, Maryland, United States

🇺🇸

Biotrial Inc., Newark, New Jersey, United States

and more 18 locations

Evaluate the Neurological Effects of EryDex on Subjects With A-T

Phase 3
Recruiting
Conditions
Ataxia Telangiectasia
Interventions
First Posted Date
2024-01-05
Last Posted Date
2025-06-29
Lead Sponsor
Quince Therapeutics S.p.A.
Target Recruit Count
106
Registration Number
NCT06193200
Locations
🇺🇸

University of California Los Angeles (UCLA), Ataxia Center and HD Center of excellence, Los Angeles, California, United States

🇺🇸

The Johns Hopkins Hospital, Division of pediatric allergy and immunology, Baltimore, Maryland, United States

🇺🇸

Biotrial Inc., Newark, New Jersey, United States

and more 18 locations

Extension Treatment Using EryDex System in Patients With AT Who Participated in the ATTeST-IEDAT-02-2015 Study

Phase 3
Terminated
Conditions
Ataxia Telangiectasia
Genetic Syndrome
First Posted Date
2018-06-20
Last Posted Date
2024-10-08
Lead Sponsor
Quince Therapeutics S.p.A.
Target Recruit Count
104
Registration Number
NCT03563053
Locations
🇮🇳

Vijaya Health Centre, Department of Neurology, Chennai, Tamil Nadu, India

🇳🇴

Norwegian National Unit for Newborn Screening, Division of Pediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway

🇬🇧

Nottingham University Hospitals NHS Trust - Queen's Medical Centre, Nottingham, Nottinghamshire, United Kingdom

and more 14 locations

Intra-Erythrocyte Dexamethasone Sodium Phosphate in Ataxia Telangiectasia Patients

Phase 3
Completed
Conditions
Nervous System Disease
Genetic Syndrome
Interventions
Drug: EryDex Low dose DSP
Drug: EryDex High dose DSP
Drug: Pooled Placebo
First Posted Date
2016-05-12
Last Posted Date
2024-05-10
Lead Sponsor
Quince Therapeutics S.p.A.
Target Recruit Count
176
Registration Number
NCT02770807
Locations
🇺🇸

UCLA-Ataxia Center and HD Center of Exellence, Los Angeles, California, United States

🇺🇸

The Ataxia-Telangiectasia Clinical Center, The Johns Hopkins Hospital, Baltimore, Maryland, United States

🇺🇸

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States

and more 19 locations

Recovery and Survival of EryDex in Non-patient Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: DSP loaded RBC using EryDex System
Drug: Sham treated RBC using the EryDex System
First Posted Date
2015-03-05
Last Posted Date
2016-02-01
Lead Sponsor
Quince Therapeutics S.p.A.
Target Recruit Count
10
Registration Number
NCT02380924
Locations
🇺🇸

Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United States

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News

Quince Therapeutics Strengthens Scientific Advisory Board with Leading Immunologist Ahead of Phase 3 Results

Quince Therapeutics appointed Dr. Hassan Abolhassani, a top-cited immunologist from Karolinska Institutet, to its Scientific Advisory Board as the ninth expert member.

Quince Therapeutics Secures Up to $22 Million to Advance Phase 3 Ataxia-Telangiectasia Trial

Quince Therapeutics raised $11.5 million in upfront proceeds with potential for an additional $10.4 million through warrant exercises to fund operations into 2026.

Quince Therapeutics' Phase 3 NEAT Trial for Ataxia-Telangiectasia Reaches 50% Enrollment Milestone

Quince Therapeutics has enrolled 46 participants in its Phase 3 NEAT trial evaluating EryDex for Ataxia-Telangiectasia treatment, with completion expected in Q2 2025 and topline results by year-end.

Quince Therapeutics' EryDex Phase 3 Trial for Ataxia-Telangiectasia Nears Enrollment Completion

Quince Therapeutics' Phase 3 NEAT trial of EryDex for Ataxia-Telangiectasia (A-T) is expected to complete enrollment in Q2 2025, marking a significant milestone.

Quince Therapeutics Presents Phase 3 ATTeST Trial Safety Data for EryDex in Ataxia-Telangiectasia

Quince Therapeutics presented safety data from the Phase 3 ATTeST trial of EryDex for Ataxia-Telangiectasia (A-T) at the Child Neurology Society Annual Meeting.

EryDex Shows Long-Term Safety in Pediatric Ataxia-Telangiectasia Patients

Quince Therapeutics' EryDex demonstrates a favorable long-term safety profile in pediatric patients with Ataxia-Telangiectasia (A-T) over a minimum of 24 months.

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