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MILLENNIUM PHARMACEUTICALS, INC.

MILLENNIUM PHARMACEUTICALS, INC. logo
🇺🇸United States
Ownership
Subsidiary
Established
1993-01-01
Employees
1K
Market Cap
-
Website
http://www.takedaoncology.com

Intravenous Ixazomib in Pediatric Participants With Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LLy)

Phase 1
Withdrawn
Conditions
Precursor Cell Lymphoblastic Leukemia-lymphoma
Interventions
First Posted Date
2019-03-25
Last Posted Date
2020-09-28
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Registration Number
NCT03888534
Locations
🇺🇸

University of Mississippi Medical Center, Jackson, Mississippi, United States

🇺🇸

Washington University School of Medicine, Saint Louis, Missouri, United States

🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

and more 4 locations

A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of TAK-954 in Healthy Adult Participants

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Drug: TAK-954 Placebo
First Posted Date
2019-03-12
Last Posted Date
2020-06-24
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Target Recruit Count
6
Registration Number
NCT03870555
Locations
🇺🇸

Celerion, Tempe, Arizona, United States

A Trial to Evaluate the Effect of the Proton Pump Inhibitor Esomeprazole on the Single-dose Pharmacokinetics (PK) of Oral TAK-906 in Healthy Adult Participants

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2019-02-21
Last Posted Date
2021-06-15
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Target Recruit Count
12
Registration Number
NCT03849690
Locations
🇺🇸

Celerion, Tempe, Arizona, United States

A Study to Assess Absolute Bioavailability (ABA) of Mobocertinib (TAK-788) and to Characterize Mass Balance, Pharmacokinetics (PK), Metabolism, and Excretion of Carbon-14 ([14C])-Mobocertinib in Male Healthy Participants

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2019-01-22
Last Posted Date
2024-02-12
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Target Recruit Count
7
Registration Number
NCT03811834
Locations
🇺🇸

Celerion, Lincoln, Nebraska, United States

Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Participants With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation (SCT)

Phase 3
Completed
Conditions
Multiple Myeloma
Interventions
First Posted Date
2018-11-21
Last Posted Date
2025-03-21
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Target Recruit Count
37
Registration Number
NCT03748953
Locations
🇨🇳

Beijing Chaoyang Hospital Capital Medical University, Beijing, Beijing, China

🇨🇳

Peking University Third Hospital, Beijing, Beijing, China

🇨🇳

Peking Union Medical College Hospital, Beijing, Beijing, China

and more 7 locations

A Study to Evaluate the Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of TAK-079 in Combination With Standard Background Therapy in Participants With Moderate to Severe Systemic Lupus Erythematosus (SLE)

Phase 1
Completed
Conditions
Systemic Lupus Erythematosus
Lupus Erythematosus, Systemic
Interventions
Drug: TAK-079 Placebo
First Posted Date
2018-10-30
Last Posted Date
2024-03-29
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Target Recruit Count
23
Registration Number
NCT03724916
Locations
🇺🇸

Pinnacle Research Group, LLC, Anniston, Alabama, United States

🇺🇸

University of Alabama at Birmingham, Birmingham, Alabama, United States

🇺🇸

University of California San Diego, La Jolla, California, United States

and more 16 locations

A Study to Assess the Relative Bioavailability, Effect of Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics (PK) of TAK-931 in Participants With Advanced Solid Tumors

Phase 1
Completed
Conditions
Neoplasms, Advanced Solid
Interventions
Drug: TAK-931 PIC
Drug: TAK-931 Tablet
First Posted Date
2018-10-17
Last Posted Date
2020-12-29
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Target Recruit Count
20
Registration Number
NCT03708211
Locations
🇳🇱

Radboud University Medical Center, Department of Medical Oncology, Nijmegen, Gelderland, Netherlands

🇳🇱

Netherlands Cancer Institute - Antoni van Leeuwenhoek, Department of Medical Oncology, Amsterdam, Noord-holland, Netherlands

🇳🇱

Leiden University Medical Center, Department of Clinical Oncology, Leiden, Zuid-holland, Netherlands

and more 1 locations

A Study of PVP001, PVP002, and PVP003 in Healthy Adults and PVP001 and PVP002 in Adults With Celiac Disease

Phase 1
Completed
Conditions
Digestive System Disease
Interventions
Other: PvP001 placebo
Drug: Maximum Feasible Dose (MFD) of PvP002
Drug: PvP003 placebo
Drug: PvP001 100 mg
Drug: Maximum Tolerated Dose (MTD) of PvP001
Other: PvP002 placebo
Drug: PvP003
Drug: PvP003 150 mg
Drug: MTD of PvP001 following 7 days of PPI treatment
Drug: PvP001 600 mg
Drug: PvP001 300 mg
Drug: PvP001 900 mg
First Posted Date
2018-10-10
Last Posted Date
2023-04-04
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Target Recruit Count
139
Registration Number
NCT03701555
Locations
🇺🇸

Anaheim Clinical Trials, Anaheim, California, United States

Vedolizumab in the Prophylaxis of Intestinal Acute Graft Versus Host Disease (aGVHD) in Participants Undergoing Allogeneic Hematopoietic Stem Cell (Allo-HSCT) Transplantation

Phase 3
Completed
Conditions
Hematopoietic Stem Cells
Interventions
First Posted Date
2018-09-04
Last Posted Date
2023-06-06
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Target Recruit Count
343
Registration Number
NCT03657160
Locations
🇺🇸

University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, United States

🇺🇸

David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, United States

🇺🇸

Children's Healthcare of Atlanta, Atlanta, Georgia, United States

and more 136 locations

A Study to Evaluate the Efficacy and Safety of TAK-906 in Adult Participants With Symptomatic Idiopathic or Diabetic Gastroparesis

Phase 2
Completed
Conditions
Idiopathic Gastroparesis
Diabetic Gastroparesis
Interventions
First Posted Date
2018-06-01
Last Posted Date
2022-11-16
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Target Recruit Count
242
Registration Number
NCT03544229
Locations
🇺🇸

Digestive Health Specialists of the Southeast, Dothan, Alabama, United States

🇺🇸

Del Sol Research Management, Tucson, Arizona, United States

🇺🇸

GW Research, Chula Vista, California, United States

and more 105 locations
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