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The Hospital for Sick Children

🇨🇦Canada

Country: 🇨🇦Canada

Ownership: Private

Established: 1875-01-01

Employees: 5K

Market Cap: -

Website: http://www.sickkids.ca

Clinical Trials

Metformin Treatment in Infants After Perinatal Brain Injury

Phase 1

Terminated

Conditions: Hypoxic Ischemic Encephalopathy of Newborn
Premature Birth

Interventions: Drug: Metformin Hydrochloride

First Posted Date: 2022-10-21

Last Posted Date: 2024-03-07

Lead Sponsor: The Hospital for Sick Children

Target Recruit Count: 1

Registration Number: NCT05590676

Locations: 🇨🇦
The Hospital for Sick Children, Toronto, Ontartio, Canada

Phenylalanine, Methionine and Histidine Requirements in TPN Fed Neonates

Not Applicable

Recruiting

Conditions: Stable Neonates
Receiving Total Parenteral Nutrition (TPN)

Interventions: Drug: Total parenteral nutrition (TPN). This is total nutrition provided by central vein.

First Posted Date: 2022-09-30

Last Posted Date: 2025-05-30

Lead Sponsor: The Hospital for Sick Children

Target Recruit Count: 60

Registration Number: NCT05562310

Locations: 🇨🇦
Glenda Courtney-Martin, Toronto, Ontario, Canada

HP 129Xe MRI for Evaluation of CLAD in Lung Transplant Recipients

Phase 2

Recruiting

Conditions: Lung Transplant Rejection

Interventions: Drug: 129Xenon

First Posted Date: 2022-09-22

Last Posted Date: 2024-11-06

Lead Sponsor: The Hospital for Sick Children

Target Recruit Count: 15

Registration Number: NCT05550662

Locations: 🇨🇦
Hospital for Sick Chilldren, Toronto, Ontario, Canada
🇨🇦
The Hospital for Sick Children, Toronto, Ontario, Canada

Pilot RCT of E4W App in Adolescents

Not Applicable

Recruiting

Conditions: Pediatric Obesity

Interventions: Device: E4W mobile app
Behavioral: Standard Care

First Posted Date: 2022-09-22

Last Posted Date: 2022-09-22

Lead Sponsor: The Hospital for Sick Children

Target Recruit Count: 32

Registration Number: NCT05548868

Locations: 🇨🇦
SickKids, Toronto, Ontario, Canada

Drug Concentrations in Breast Milk and Prediction of Blood Levels of the Breastfed Infants

Completed

Conditions: Breast Feeding

Interventions: Drug: either of Atenolol, Bupropion, Brivaracetam, Escitalopram, Fluconazole, Lacosamide, Lamotrigine, Levetiracetam, Methotrexate or Ezetimibe

First Posted Date: 2022-09-16

Last Posted Date: 2024-04-10

Lead Sponsor: The Hospital for Sick Children

Target Recruit Count: 39

Registration Number: NCT05543122

Locations: 🇨🇦
Mehzabin Rahman, Toronto, Ontario, Canada

SleepPOSAtive Trial

Not Applicable

Completed

Conditions: Obstructive Sleep Apnea of Child

Interventions: Device: Positional Sleep Belt
Device: Control

First Posted Date: 2022-08-12

Last Posted Date: 2024-01-17

Lead Sponsor: The Hospital for Sick Children

Target Recruit Count: 24

Registration Number: NCT05499455

Locations: 🇨🇦
The Hospital for Sick Children, Toronto, Ontario, Canada

A Mindfulness-Based Intervention to Improve CPAP

Not Applicable

Active, not recruiting

Conditions: Obstructive Sleep Apnea (Moderate to Severe)
Obstructive Sleep Apnea

Interventions: Other: Mindfulness Program

First Posted Date: 2022-08-12

Last Posted Date: 2025-05-21

Lead Sponsor: The Hospital for Sick Children

Target Recruit Count: 102

Registration Number: NCT05499286

Locations: 🇨🇦
Hospital for Sick Children, Toronto, Ontario, Canada

Nutrition Recommendation Intervention trialS in Children's Healthcare

Not Applicable

Not yet recruiting

Conditions: Nutrition
Diabetes
Health Risk Behaviors
Breastfeeding
Exclusive Breastfeeding
Obesity, Childhood

Interventions: Other: Control Group
Other: Childcare Navigator
Other: Lactation Consultant
Other: Lactation Consultant Support and Childcare Navigator Support

First Posted Date: 2022-07-28

Last Posted Date: 2023-11-21

Lead Sponsor: The Hospital for Sick Children

Target Recruit Count: 620

Registration Number: NCT05477628

Keeping in Touch (KiT) With Youth as They Transition to Adult Type 1 Diabetes Care

Not Applicable

Active, not recruiting

Conditions: Diabetes Mellitus, Type 1

Interventions: Other: eHealth Tool

First Posted Date: 2022-06-28

Last Posted Date: 2025-04-24

Lead Sponsor: The Hospital for Sick Children

Target Recruit Count: 234

Registration Number: NCT05434754

Locations: 🇨🇦
Oak Valley Health, Markham, Ontario, Canada
🇨🇦
Trillium Health Partners, Mississauga, Ontario, Canada
🇨🇦
Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada

and more 3 locations

Thal-Fabs: Reduced Toxicity Conditioning for High Risk Thalassemia

Phase 1

Recruiting

Conditions: Thalassemia in Children

Interventions: Drug: Abatacept
Drug: Sirolimus

First Posted Date: 2022-06-21

Last Posted Date: 2023-12-19

Lead Sponsor: The Hospital for Sick Children

Target Recruit Count: 20

Registration Number: NCT05426252

Locations: 🇨🇦
Yogi Chopra, Toronto, Ontario, Canada

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