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Travere Therapeutic

Travere Therapeutic logo
🇺🇸United States
Ownership
Public
Established
2008-02-07
Employees
380
Market Cap
-
Website
http://www.travere.com
Introduction

Travere Therapeutics, Inc. is a biopharmaceutical company. It engages in the identification, development, commercialization, and distribution of therapies to people living with rare diseases. The firm's products include Chenodal, Cholbam, and Thiola. The company was founded by Martin Shkreli on February 7, 2008 and is headquartered in San Diego, CA.

Clinical Trials

39

Active:28
Completed:4

Trial Phases

3 Phases

Phase 1:27
Phase 2:4
Phase 3:5

Drug Approvals

1

FDA:1

Drug Approvals

FILSPARI

Approval Date
Feb 17, 2023
FDA

Clinical Trials

Distribution across different clinical trial phases (36 trials with phase data)• Click on a phase to view related trials

Phase 1
27 (75.0%)
Phase 3
5 (13.9%)
Phase 2
4 (11.1%)

A Phase 3 Long-term Extension Study to Assess the Long-term Safety and Efficacy of Pegtibatinase Treatment in Participants ≥5 to ≤65 Years of Age With Classical Homocystinuria (HCU) (ENSEMBLE)

Phase 3
Conditions
Homocystinuria
Interventions
First Posted Date
2024-05-29
Last Posted Date
2025-04-11
Lead Sponsor
Travere Therapeutics, Inc.
Target Recruit Count
100
Registration Number
NCT06431893
Locations
🇺🇸

Travere Investigational Site, Philadelphia, Pennsylvania, United States

🇺🇸

Travere Investigational Site - Virtual Site, Morrisville, North Carolina, United States

A Study to Investigate Efficacy and Safety of Pegtibatinase Compared With Placebo in Participants ≥12 to ≤65 Years of Age With Classical Homocystinuria (HCU) Due to Cystathionine Beta Synthase Deficiency Receiving Standard of Care Treatment

Phase 3
Active, not recruiting
Conditions
Homocystinuria
Interventions
Other: Placebo
First Posted Date
2024-02-07
Last Posted Date
2025-04-09
Lead Sponsor
Travere Therapeutics, Inc.
Target Recruit Count
70
Registration Number
NCT06247085
Locations
🇺🇸

Travere Investigational Site - Virtual Site, Morrisville, North Carolina, United States

A Study to Investigate Safety and Effect of Sparsentan in Combination With SGLT2 Inhibition in Participants With IgAN

Phase 2
Completed
Conditions
Immunoglobulin A Nephropathy
Interventions
First Posted Date
2023-05-12
Last Posted Date
2025-06-08
Lead Sponsor
Travere Therapeutics, Inc.
Target Recruit Count
48
Registration Number
NCT05856760
Locations
🇭🇰

Travere Investigational Site, Tsuen Wan, Hong Kong

🇺🇸

Travere Investigation SIte, Clifton Park, New York, United States

Study to Evaluate the Pharmacokinetics of Oral Sparsentan Suspension

Phase 1
Completed
Conditions
Healthy Subjects
Interventions
First Posted Date
2022-09-30
Last Posted Date
2022-09-30
Lead Sponsor
Travere Therapeutics, Inc.
Target Recruit Count
47
Registration Number
NCT05562362
Locations
🇬🇧

Travere Investigational Site, Nottingham, United Kingdom

Humanistic Burden of (FSGS) Focal Segmental Glomerulosclerosis and IgAN (Immunoglobulin A Nephropathy)

Completed
Conditions
Immunoglobulin A Nephropathy
Focal Segmental Glomerulosclerosis
First Posted Date
2022-01-21
Last Posted Date
2024-02-21
Lead Sponsor
Travere Therapeutics, Inc.
Target Recruit Count
487
Registration Number
NCT05200871
Locations
🇪🇸

Travere Investigational Site, Madrid, Spain

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